THE EFFICACY OF VARIOUS THIOLS AS ANTIDOTES TO LEWISITE

1950 ◽  
Vol 28e (4) ◽  
pp. 135-142 ◽  
Author(s):  
S. D. Simpson ◽  
L. Young
Keyword(s):  
The Other ◽  
Toxic Action ◽  
A Site ◽  
Antidotal Activity

The following thiols were tested for their effectiveness in counteracting the systemic toxic action of lewisite (β-chlorovinyldichloroarsine) in the rat: 1- and 2-mercaptopropane, 2-mercaptoethanol, 1,2-dimercaptoethane, 1,2- and 1,3-dimercaptopropane, 1,2,3-trimercaptopropane, 1,2-dimercapto-n-butane, 2,3-dimercaptopropanol, 1,3-dimercapto-2-propanol, 2,2′-dimercaptodiethyl ether, 2,2′-dimercaptodiisopropyl ether, and 3,3′-dimercaptodipropyl ether. The toxicity and volatility of these compounds were also studied.The tests of antidotal activity were conducted by applying the thiol to the skin at a site which had been dosed with approximately twice the LD50 of lewisite. Under these conditions the monothiols gave no evidence of antidotal activity whereas all the dithiols and the trithiol studied showed some activity. 2,3-Dimercaptopropanol (BAL) and its isomer, 1,3-dimercapto-2-propanol, were much more effective as antidotes to lewisite than any of the other compounds tested. Not only did 2,3-dimercaptopropanol show a somewhat higher antidotal activity than its isomer, but it was also found to be much less toxic.

Actualisation du catalogue des pteridophytes du Nord Ouest Algerien (region de Tlemcen). An update of the cheklist of pteridophytes from Nordwest Algeria (Tlemcen region)

2013 ◽  
Vol 38 ◽  
pp. 33-39 ◽  
Author(s):  
Boumediene Medjahdi ◽  
Assia Ltreuch-Belarouci ◽  
Rémy Prelli
Keyword(s):  
Nous Avons ◽  
Genetic Resources ◽  
Threatened Species ◽  
The Other ◽  
Natural Distribution ◽  
Ecological Characteristics ◽  
Statutory Protection ◽  
Ouest Algérien ◽  
A Site ◽  
Ressources Génétiques

Français. Un inventaire des ptéridophytes a été entrepris dans les forêts de la région de Tlemcen. L’inventaire de ces populations constitue une étape importante pour le développement des stratégies de conservation des ressources génétiques et de la diversité de ces populations sur l’ensemble de leur aire de distribution naturelle. Nous avons ainsi effectué le recensement et l’identification des fougères existantes dans la région de Tlemcen. Au total, plusieurs stations dont les caractéristiques écologiques diffèrent d’un site à un autre ont été prospectées, cela a permis l’identification de 26 taxons (dont 5 exceptionnellement rare). La création de réserves naturelles forestières renforcée par une protection réglementaire des espèces les plus menacées est nécessaire pour le maintien de ces communautés si particulières. English. An inventory of Pteridophyta was begun in the forests of the Tlemcen region. The inventory of these populations constitutes an important stage for the developement of the strategies of preservation of the genetic resources and the diversity of these populations on their whole area of natural distribution. We so made the inventory and the identification of the existing ferns in the region of Tlemcen. On the whole, several stations the ecological characteristics differ from a site in the other one were canvassed; they allowed the identification of 26 taxes (among which 5 exceptionally rare). The creation of forest nature reserves strengthened by a statutory protection of the most threatened species is necessary for the preservation of these particular communities.

scholarly journals β-Li0.37Na0.63Fe(MoO4)2

2014 ◽  
Vol 70 (2) ◽  
pp. i9-i10 ◽  
Author(s):  
Amira Souilem ◽  
Mohamed Faouzi Zid ◽  
Ahmed Driss
Keyword(s):  
Crystal Structure ◽  
Solid State ◽  
Solid State Reaction ◽  
Title Compound ◽  
General Position ◽  
Site Occupancy ◽  
The Other ◽  
Main Structure ◽  
Axis Direction ◽  
A Site

The title compound, lithium/sodium iron(III) bis[orthomolybdate(VI)], was obtained by a solid-state reaction. The main structure units are an FeO6octahedron, a distorted MoO6octahedron and an MoO4tetrahedron sharing corners. The crystal structure is composed of infinite double MoFeO11chains along theb-axis direction linked by corner-sharing to MoO4tetrahedra so as to form Fe2Mo3O19ribbons. The cohesion between ribbonsviamixed Mo—O—Fe bridges leads to layers arranged parallel to thebcplane. Adjacent layers are linked by corners shared between MoO4tetrahedra of one layer and FeO6octahedra of the other layer. The Na+and Li+ions partially occupy the same general position, with a site-occupancy ratio of 0.631 (9):0.369 (1). A comparison is made withAFe(MoO4)2(A= Li, Na, K and Cs) structures.

scholarly journals MICRURGICAL STUDIES IN CELL PHYSIOLOGY

1926 ◽  
Vol 10 (1) ◽  
pp. 9-21 ◽  
Author(s):  
Paul Reznikoff
Keyword(s):  
Heavy Metals ◽  
Metal Cation ◽  
Surface Membrane ◽  
The Other ◽  
Contractile Vacuole ◽  
Toxic Action ◽  
Cell Physiology ◽  
Relative Toxicity ◽  
A Cell

I. Plasmalemma. 1. The order of toxicity of the salts used in these experiments on the surface membrane of a cell, taking as a criterion viability of amebæ immersed in solutions for 1 day, is HgCl2, FeCl3> AlCl3> CuCl2> PbCl2> FeCl2. Using viability for 5 days as a criterion, the order of toxicity is PbCl2> CuCl2> HgCl2> AlCl3> FeCl3> FeCl2. 2. The rate of toxicity is in the order FeCl3> HgCl2> AlCl3> FeCl2> CuCl2> PbCl2. 3. The ability of amebæ to recover from a marked tear of the plasmalemma in the solutions of the salts occurred in the following order: AlCl3> PbCl2> FeCl2> CuCl2> FeCl3> HgCl2. II. Internal Protoplasm. 4. The relative toxicity of the salts on the internal protoplasm, judged by the recovery of the amebæ from large injections and the range over which these salts can cause coagulation of the internal protoplasm, is in the following order: PbCl2> CuCl2> FeCl3> HgCl2> FeCl2> AlCl3. 5. AlCl3 in concentrations between M/32 and M/250 causes a marked temporary enlargement of the contractile vacuole. FeCl2, FeCl3, and CuCl3 produce a slight enlargement of the vacuole. 6. PbCl2, in concentrations used in these experiments, appears to form a different type of combination with the internal protoplasm than do the other salts. III. Permeability. 7. Using the similarity in appearance of the internal protoplasm after injection and after immersion to indicate that the surface is permeable to a substance in which the ameba is immersed, it is concluded that AlCl3 can easily penetrate the intact plasmalemma. CuCl2 also seems to have some penetrating power. None of the other salts studied give visible internal evidence of penetrability into the ameba. IV. Toxicity. 8. The toxic action of the chlorides of the heavy metals used in these experiments, and of aluminum, is exerted principally upon the surface of the cell and is due not only to the action of the metal cation but also to acid which is produced by hydrolysis.

Completing a Site: The Other 90%

2011 ◽  
pp. 747-802
Author(s):  
Benjamin Melançon
Keyword(s):  
The Other ◽  
A Site

scholarly journals Continuity through Renewal: John Dewey, the International Institute in Spain, and Resisting the Assault on the Humanities

2020 ◽  
Vol 2 (1) ◽  
pp. 23-38
Author(s):  
Andrew Bennett
Keyword(s):  
Civil War ◽  
Educational Reform ◽  
John Dewey ◽  
Liberal Democracy ◽  
The Other ◽  
International Institute ◽  
Humanities Education ◽  
Shared Space ◽  
Democratic Societies ◽  
A Site

This paper marks the relation between humanities education and democracy as one of mutual necessity, since the pragmatic value of each is dependent on the other to be recognizable and realizable. Such an understanding is drawn from the ideas of the American philosopher and educator John Dewey. Dewey’s system clearly reveals the nature of the stakes of the assault on the humanities; it also indicates the educational measures democratic societies should take in response. By instantiating the “conjoint communicated experience” of democracy in a public, shared space in which differences are respected, human meanings are explored, and the expansion of knowledge and experience is valued as an end in itself, the humanities classroom emerges as a site of social renewal, as well as one of resistance to illiberalism. In order to present such a site in a manner befitting Dewey’s pragmatism, a lesser-known, local example of the value of humanities education is examined in this paper: that of the International Institute in Spain, located in Madrid. Beginning with its founding as a school for girls by Boston missionaries in 1892, and through its role at the center of a network of institutions invested in progressive educational reform in Spain during the pre-civil war period, IIE stands as a testament to the continuity through renewal that defines both liberal democracy and humanities education.

scholarly journals Recording plant status and regeneration during single visits

2019 ◽  
Vol 1 (4) ◽  
pp. 283-291
Author(s):  
Kevin J. Walker ◽  
Simon Leach ◽  
Chris Preston ◽  
Thomas Humphrey ◽  
Trevor James ◽  
...  
Keyword(s):  
Plant Species ◽  
Native Species ◽  
Objective Measure ◽  
The Other ◽  
A Site

Information on the origin (status) and regeneration of plant species improves our understanding of native distributions and the establishment of non-native species. However, current categories used to record status in Britain and Ireland, whilst conceptually informative, rely on a knowledge of persistence that is impossible to assess objectively during a single (one-off) recording visit. We propose five alternative categories that focus on origin (how a species arrived at a site) rather than persistence. The first two categories apply to nationally native taxa: (1) populations that are unequivocally native and (2) those that are likely to have been introduced and/or are spreading for reasons that are obscure. The other three categories cover the occurrences of any taxon, native or non-native, that is known or suspected to have been introduced to a site: (3) introductions with unknown/obscure origins; (4) deliberate introductions; and (5) accidental introductions. For the introduced categories 3-5 we recommend that botanists also record signs of regeneration, i.e. seedlings or widely scattered patches, as a more objective measure whether a species is likely to be self-sustaining in a given locality.

Paleomagnetic history of the Mealy dykes of Labrador, Canada

1983 ◽  
Vol 20 (12) ◽  
pp. 1818-1833 ◽  
Author(s):  
J. K. Park ◽  
R. F. Emslie
Keyword(s):  
The Other ◽  
Magnetic Mineral ◽  
Magnetic Minerals ◽  
Linear Distribution ◽  
Tectonic Zone ◽  
Magnetic Components ◽  
History Of ◽  
Component C ◽  
A Site

Paleomagnetic analysis of the Mealy diabase dykes of Labrador reveals magnetizations that predate the Grenville event at about 1000 Ma. These dykes intrude the Mealy Mountains anorthositic complex in the Grenville Structural Province. They are well south of the Grenville Front Tectonic Zone, but were apparently never subjected to temperatures as high as 500 °C during their post-consolidation history.Four distinct magnetic components were uncovered by thermal and alternating field treatments and a fifth remained unresolved. The major magnetic mineral present, titanomagnetite, is thought to record two magnetic directions acquired during cooling from magmatic temperatures. These are B (D = 305°, I = −76°; N = 18 sites; κ = 12; α95 = 11°) and A (D = 095°, I = +52°; N = 20 sites; κ = 46; α95 = 5°). Component B has much within-site dispersion. The other two components, C (D = 274°, I = −47°; N = 10 sites; κ = 15; α95 = 13°) and D (D = 292°, I = −74°; κ = 5; α95 = 31°), probably reside in magnetite and pyrrhotite, respectively. Component C, antiparallel to A, was probably acquired at about the same time as A. We suggest that C and A represent the first stable magnetizations retained by the dykes following an extensive period of cooling and re-equilibration of the magnetic minerals. Components B and D, which agree in direction, represent a later stage of cooling.Component B has a pole at 148°E, 34°S (δp = 18°, δm = 19°) in agreement with regional metamorphic poles from the Grenville; A, however, has a pole at 173°W, 23°S (δp = 5°, δm = 7°), which apparently "sees through" the peak in Grenville activity. The A site poles have a linear distribution along the Keweenawan Track and probably relate to an age between 1000 and 1150 Ma.

Trakhtemirov: A Fortified City site on the Dnieper

2007 ◽  
Author(s):  
YU. V. BOLTRIK ◽  
E. E. FIALKO
Keyword(s):  
Iron Age ◽  
Central Place ◽  
The Other ◽  
Early Iron Age ◽  
The West ◽  
Trade Routes ◽  
Scythian Period ◽  
A Site ◽  
The City

This chapter focuses on Trakhtemirov, one of the most important ancient settlements of the Early Iron Age in the Ukraine. During the ancient period, the trade routes and caravans met at Trakhtemirov which was situated over the three crossing points of the Dneiper. Its location on the steep heights assured residents of Trakhtemirov security of settlement. On three sides it was protected by the course of the Dnieper while on the other side it was defended by the plateau of the pre-Dneiper elevation. The ancient Trakhtemirov city is located around 100 km below Kiev, on a peninsula which is jutted into the river from the west. Trakhtemirov in the Early Iron Age was important as it was the site of the Cossack capital of Ukraine. It was also the site of the most prestigious artefacts of the Scythian period and a site for various items of jewellery, tools and weaponry. The abundance of artefacts in Trakhtemirov suggests that the city is a central place among the scattered sites of the middle course of the Dneiper.

Situated literacy : a study of family literacy in Aotearoa/New Zealand

2021 ◽  
Author(s):  
◽  
Juliet Suzanne Smith
Keyword(s):  
New Zealand ◽  
Social Context ◽  
Generational Differences ◽  
Family Literacy ◽  
The Other ◽  
Literacy Experiences ◽  
Aotearoa New Zealand ◽  
The Family ◽  
Situated Literacy ◽  
A Site

<p>This study investigated the family as a site for literacy. The theoretical approach is that all literacy is situated in a social context. Eleven parents were interviewed about literacy use and practices both in their present families. The parents were from India, Sri Lanka, Britain and Aotearoa/ New Zealand. The study explored generational differences as well as aspects of diversity among the families. While there were similarities in the uses of literacy across the generations, diversity was evident in the differences in purpose between the Pakeha families and the others. For the Paheka the purpose of reading was for pleasure while the other parents stressed the importance of reading for moral messages and guides to behaviour. Parents spoke more often about reading than about writing, they recalled favourite books, especially those by Enid Blyton, and reported stories they told their own children. It is suggested that teachers might explore their own literacy experiences to better understand the issues of both literacy and diversity.</p>

Situated literacy : a study of family literacy in Aotearoa/New Zealand

2021 ◽  
Author(s):  
◽  
Juliet Suzanne Smith
Keyword(s):  
New Zealand ◽  
Social Context ◽  
Generational Differences ◽  
Family Literacy ◽  
The Other ◽  
Literacy Experiences ◽  
Aotearoa New Zealand ◽  
The Family ◽  
Situated Literacy ◽  
A Site

<p>This study investigated the family as a site for literacy. The theoretical approach is that all literacy is situated in a social context. Eleven parents were interviewed about literacy use and practices both in their present families. The parents were from India, Sri Lanka, Britain and Aotearoa/ New Zealand. The study explored generational differences as well as aspects of diversity among the families. While there were similarities in the uses of literacy across the generations, diversity was evident in the differences in purpose between the Pakeha families and the others. For the Paheka the purpose of reading was for pleasure while the other parents stressed the importance of reading for moral messages and guides to behaviour. Parents spoke more often about reading than about writing, they recalled favourite books, especially those by Enid Blyton, and reported stories they told their own children. It is suggested that teachers might explore their own literacy experiences to better understand the issues of both literacy and diversity.</p>

Sign in / Sign up

Export Citation Format

Share Document