THE EFFECT OF BARBITURATES AND OTHER SUBSTANCES ON MOTION SICKNESS IN DOGS

R. L. Noble

doi:10.1139/cjr48e-016

THE EFFECT OF BARBITURATES AND OTHER SUBSTANCES ON MOTION SICKNESS IN DOGS

Canadian Journal of Research ◽

10.1139/cjr48e-016 ◽

1948 ◽

Vol 26e (5) ◽

pp. 283-294 ◽

Cited By ~ 4

Author(s):

R. L. Noble

Keyword(s):

Motion Sickness ◽

Large Series ◽

Additive Effect ◽

Compound A ◽

Other Substances ◽

Anesthetic Property

A large series of barbiturates and other substances have been tested for their ability to prevent motion sickness in dogs. Many compounds were found to possess this activity, which was not related to the anesthetic property of the compound. A number of barbiturates were found to be considerably more active than V-12, which was used as a standard. Pyridoxine, hyoscine, and streptomycin were inactive in the tests described. Bulbocapnine possessed half the potency of V-12 and showed an additive effect when the two substances were given together.

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Aspiration cytology and transmission electron microscopy (TEM): A novel tissue-collection technique with useful diagnostic applications

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100110751 ◽

1984 ◽

Vol 42 ◽

pp. 90-93

Author(s):

J.A. Maksem ◽

C. VanDyke ◽

H.W. Carter ◽

C.F. Galang

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Diagnostic Technique ◽

Needle Aspiration ◽

Large Series ◽

Aspiration Cytology ◽

Fine Needle ◽

Transmission Electron ◽

Diagnostic Applications ◽

Microscopic Slide

In the last decade fine needle aspiraration biopsy has gained recognition as a valuable diagnostic technique, and its benefits have been demonstrated in large series of patients with almost every type of tumor (1,2). The usual way to collect cellular material from needle-aspiration biopsies is to discharge the needle and syringe contents onto a microscopic slide and smear the material with another slide. The entire specimen is contained on the slides prepared at the time of biopsy. Serious technical difficulties are inherent to this method. 1) Inconsistent fixation, 2) drying artifact, 3) loss of tissue fragments, 4) inability to confirm impressions by a “second method”, and 5) retention of significant diagnostic material in the needle hub. Our technique avoids these difficulties.

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Vestibular Function and Motion Sickness Susceptibility: Videonystagmographic Evidence From Oculomotor and Caloric Tests

American Journal of Audiology ◽

10.1044/2020_aja-19-00050 ◽

2020 ◽

Vol 29 (2) ◽

pp. 188-198

Author(s):

Cynthia G. Fowler ◽

Margaret Dallapiazza ◽

Kathleen Talbot Hadsell

Keyword(s):

Phase Velocity ◽

Motion Sickness ◽

Repeated Measures ◽

Short Form ◽

Vestibular Function ◽

Slow Phase ◽

Test Results ◽

Normal Range ◽

Slow Phase Velocity ◽

Caloric Tests

Purpose Motion sickness (MS) is a common condition that affects millions of individuals. Although the condition is common and can be debilitating, little research has focused on the vestibular function associated with susceptibility to MS. One causal theory of MS is an asymmetry of vestibular function within or between ears. The purposes of this study, therefore, were (a) to determine if the vestibular system (oculomotor and caloric tests) in videonystagmography (VNG) is associated with susceptibility to MS and (b) to determine if these tests support the theory of an asymmetry between ears associated with MS susceptibility. Method VNG was used to measure oculomotor and caloric responses. Fifty young adults were recruited; 50 completed the oculomotor tests, and 31 completed the four caloric irrigations. MS susceptibility was evaluated with the Motion Sickness Susceptibility Questionnaire–Short Form; in this study, percent susceptibility ranged from 0% to 100% in the participants. Participants were divided into three susceptibility groups (Low, Mid, and High). Repeated-measures analyses of variance and pairwise comparisons determined significance among the groups on the VNG test results. Results Oculomotor test results revealed no significant differences among the MS susceptibility groups. Caloric stimuli elicited responses that were correlated positively with susceptibility to MS. Slow-phase velocity was slowest in the Low MS group compared to the Mid and High groups. There was no significant asymmetry between ears in any of the groups. Conclusions MS susceptibility was significantly and positively correlated with caloric slow-phase velocity. Although asymmetries between ears are purported to be associated with MS, asymmetries were not evident. Susceptibility to MS may contribute to interindividual variability of caloric responses within the normal range.

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