THE EFFECT OF ACUTE STARVATION ON THE BODY ORGANS OF THE ADULT WHITE RAT, WITH ESPECIAL REFERENCE TO THE ADRENAL GLANDS

1946 ◽  
Vol 24e (2) ◽  
pp. 37-48 ◽  
Author(s):  
A. T. Cameron ◽  
J. Carmichael

When rats are starved by withholding all food, though giving water, they develop, two or threes days before death a typical behaviour syndrome, in winch at first there is increased activity, and subsequently, in old animals, marked immobility. At this pre-mortal stage in old animals, or the corresponding stage in younger rats, they have lost 30% or more of their body weight, and if they killed the adrenals are found to be enlarged and discoloured to a dark grey or dark dirty grey. These enlarged glands contain an increased amount of water though their solid content remains practically unaltered, the change representing an increase in the water content of the cells (possibly confined to the cortex). The glomerular zone is diminished in thickness, and the reticular zone also shows abnormality. Animals killed before they have lost 30% of their body weight still have normal adrenals (normal in size, weight, water content, and colour). The enlargement produced m the pre-mortal stage of inanition is a pathological process and is not a hypertrophy. Data in the literature suggest that certain types of adrenal enlargement such as that produced by deficiency of the B-complex vitamins may be similar in nature. The kidneys, heart, and gonads of acutely starved rats tend to lose weight more slowly than the whole body; the liver and spleen more rapidly; and the thyroid at about the same rate.

1951 ◽  
Vol 42 (2) ◽  
pp. 399-418 ◽  
Author(s):  
S. Pradhan ◽  
S. C. Bhatia

The relationship was studied between susceptibility of a number of different species of insects to HCN fumigation and the recovery of HCN from them immediately after fumigation.The test insects used were Tribolium castaneum, seventh stage caterpillars of Corcyra cephalonica, first-and second-instar nymphs of Drosicha sp., third-and fourthinstar nymphs of Drosicha sp. and adult females of Drosicha sp.The apparatus and methods used in the fumigation and in the recovery of HCN from the fumigated insects are fully described.Preliminary expsriments showed that the processes of distillation and redistillation did not affect the recovery of HCN but that the result obtained for recovery from distillation could be affected if some volatile reducing substance were produced and carried over to the distillate. It was found that this did actually take place in the case of one of the test insects—T. castaneum—but that redistillation got rid of the impurity.In the main experiments it was shown that, on the assumption that the concentration of HCN to which insects are exposed is the effective dosage, the susceptibility of the test insects varied in the following descending order : firstand second-stage nymphs of Drosicha sp. > third- and fourth-stage nymphs of Drosicha sp.>C. cephalonica> T. castaneum>the adult females of Drosicha sp.When the same insects were arranged in descending order of the quantities of HCN recovered per 100 gm. of body weight, the order was identical except for the nymphs of Drosicha sp. which occupied a different relative position. The two categories of nymphs of Drosicha sp. were found to occupy a different relative position again with regard to the other three test insects when exposed to a superlethal concentration and assessed for recovery of HCN per 100 gr. body weight.Parallel batches of T. castaneum and C. cephalonica were fumigated and the HCN was recovered from the dead and survivors. More HCN was recovered from the dead insects than from those that survived.Both recovery and sorption of HCN were estimated separately in parallel batches of insects (adult females of Drosicha sp. and C. cephalonica). Recovery was found to be less than sorption showing that a part of the HCN absorbed is converted into a non-recoverable state. Further, that the weight of HCN sorbed per gram body weight of adult females of Drosicha sp. is much less than in the case of C. cephalonica under similar conditions of fumigation and that the amount of HCN converted into non-recoverable products is less in Drosicha adults than in C. cephalonica.A comparison of the water content of T. castaneum, C. cephalonica and Drosicha sp. (adults) showed that there was a positive correlation between water content and higher susceptibility to HCN and greater recovery of HCN was also indicated. It is suggested that this may be a factor in the “ Surface Resistance ” of an insec to a fumigant.The observations of previous workers that larger amounts are sorbed by or recovered (after fumigation) from more susceptible species than for those less susceptible was corroborated by the results obtained with C. cephalonica, T. castaneum and adult females of Drosicha sp. but not with those from nymphs of Drosicha sp.When dosage-mortality graphs were prepared by taking the amount of HCN recovered per gram body weight as an index of internal dose, the order of resistance of different test insects based on this new criterion was found to be entirely different from that based on the usual criterion of the concentration of HCN in the fumatorium being the index of effective dosage.These apparently anomalous observations may be explained by assuming that the resistance shown by an insect in an actual fumigation operation, i.e., to the concentration of HCN to which it is exposed (external dose) is what may be called the total “ Effective Resistance ” and that this “ Effective Resistance ” is the resultant of (a) “ Surface Resistance ” to the entry of fumigant and (b) “ Internal Resistance ” to the amount of HCN which actually gains entry into the body in some way or other. Thus the “Effective Resistance ” of an insect may be due to a combination either of low “ Surface Resistance ” and high “ Internal Resistance ”, giving a very low “ Effective Resistance ” as in the case of C. cephalonica, or vice versa giving the maximum “ Effective Resistance ” as in adult females of Drosicha sp. The lower recovery of HCN from the nymphs of Drosicha sp., although they were more susceptible to fumigation than C. cephalonica, is explained by their higher “ Surface Resistance ” combined with a very much lower “ Internal Resistance ”, leading to a lower “ Effective Resistance ”.


2016 ◽  
Vol 7 (2) ◽  
pp. 26
Author(s):  
Wanmi Nathaniel ◽  
Onyeanusi I. Barth ◽  
Nzalak J. Oliver ◽  
Aluwong Tanang

<p class="jbls-body"><span lang="EN-GB">A total of one hundred and seventy-three fertilized eggs were used for morphometry, gross and histological studies. At day 4 of incubation, the mean body weight of the helmeted guinea fowl embryo was 0.6401 ± 0.0211 g. It was at day 10 of incubation that there was an increase in the whole body weight of the embryo to be 0.8650 ± 0.676 g. The whole brain weight indicated relative increased at day 4 as compared to that of the whole body weight. Graphically, there were steady increase in the body, brain and optic lobe weights. Histologically, cells and neurones that make up the optic lobe is probably as a result of the migration of immature cells from the ventricular neuroepithelium. </span></p>


1956 ◽  
Vol 33 (1) ◽  
pp. 29-44 ◽  
Author(s):  
BETTY I. ROOTS

1. The water content of Lumbricus terrestris, after keeping on moist filter-paper for 3 or 4 days, is 84.8% of its body weight. That of Allolobophora chlorotica is 80% of its body weight. Both species can survive a loss of 60% of the body weight, but not much more. 2. Earthworms of the species A. chlorotica, A. terrestris f. longa, Dendrobaena subrubicunda, L. rubellus and L. terrestris are all able to survive from 31 to 50 weeks in soil totally submerged beneath aerated water. The same species, and A. caliginosa can survive for 72-137 days in aerated tap water without food. 3. Garden specimens of A. chlorotica make U-shaped burrows in soil beneath water. They do not irrigate either the burrows or glass tubes. Egg-cocoons of A. chlorotica, taken from culture pots of soil, will hatch under water and the young worms will feed and grow though totally immersed.


1959 ◽  
Vol 196 (3) ◽  
pp. 512-516 ◽  
Author(s):  
Adam Anthony ◽  
Eugene Ackerman ◽  
G. K. Strother

Analyses were made of myoglobin content of rat skeletal and cardiac muscle following continuous exposure to simulated altitudes of 18,000 feet for a 2–10-week period. About five dozen rats were used. Acclimatization was associated with an increase in the myoglobin concentration of thigh, diaphragm, gastrocnemius and heart muscles. Total myoglobin content, however, increased during acclimatization in cardiac muscle but not in the three skeletal muscles. This finding together with the body weight changes and muscle weight changes suggested that the increases in myoglobin concentration of skeletal muscle may be merely a reflection of a decreased water content of muscles.


In this Paper tibia bone is generated and analyzed using finite element method by applying static load on it and various stress concentrated regions in tibia bone is identified and analyzed for stresses at various locations by taking Von Misses stress and displacement. The body of the human being consists of many bones and muscles and many instances, the application of different loads leads to the damage in the bone. So it is necessary to evaluate the effect of applied loads on the bone of human body. In most of the cases whole body weight is carried by the tibia bone which is below the knee roll. So it’s necessary to estimate the strength of the tibia bone to carry the body weight. The behavior of the tibia bone under dynamic and static load is necessary for the orthopedic doctors during the treatment of ankle trauma and fractures, but in this paper the study is limited to only static and find out the aspects like Von Misses stress and displacement of tibia bone model under different forces of 800N, 810N, 820N &830N and from the result its understood that both Von Misses stress and displacement are directly proportional to the applied force and the value of Von misses stress in result is less than the maximum value i.e 18MPa for calcium, hence its concluded that generated bone model can withstand the applied force in the range of 800 to 850N


2012 ◽  
Vol 18 (1) ◽  
pp. 63-64
Author(s):  
Md Rafiqul Bari ◽  
TC Das ◽  
Anwar Hussain ◽  
Md Mazharul Islam ◽  
Abul Kalam Mohommad Yousuf

In case of hanging the process of respiration i.e. the exchange of air between the atmosphere and the alveoli of lungs is prevented by ligature in neck, leading to asphyxia and death. Hanging may be complete/incomplete (partial) where the constricting forces are the body weight or even only the weight of the head. In complete hanging whole body is suspended, no part of the body touches the ground. Complete hanging is suicidal in nature unless otherwise proved. In partial hanging any part of the body touches the ground. Partial hanging is suicidal (100%) in nature & there is no 2nd thought. Generally Medical and non-medical personals think that complete hanging may be suicidal, but partial hanging is definitely homicidal in nature which is not the actual fact. Hanging with signs of torture in various parts of body goes in favour of (provoked) suicidal nature. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12244 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 63-64


Author(s):  
O. I. Lebid ◽  
K. M. Duda

The article presents the results of clinical examination of periodontal tissues in adolescents against the background of alimentary-constitutional obesity.The aim of the study – to investigate the features of the course of diseases of the periodontal tissue according to clinical indices in persons with alimentary-constitutional obesity.Materials and Methods. As a result of the survey, 95 adolescents aged 16–18 years old were included to study the features of the course of infl ammatory diseases of periodontal tissues in adolescents with alimentary-constitutional obesity 76 adolescents and 19 adolescents with harmonious physical development. To clarify the diagnosis, «excessive body weight» was determined by weight and height of the patient, and measured the circumference of the waist and hips. In the future, the body mass index (BMI) was calculated as the ratio of body weight in kg to square of growth in m2. Diagnosis of excess body weight was confi rmed with BMI less than 30kg/m2. The evaluation of the condition of periodontal tissues was carried out according to subjective and objective criteria (clinical parameters, index score). For the verifi cation of the pathological process in the periodontium, the classifi cation of M. F. Danilevskyi (1994) was used. The state of periodontal tissues was described using a traditional index score. Statistical processing of the results was carried out using commonly used methods of variation statistics with a help of personal computer using a statistical software package «Statistica 8.0» («Statsoft», USA). The probability level was estimated at 95 % (p<0.05) using Student’s t criterion.Conclusions. Consequently, the clinical indicators of the state of periodontal tissues in the context of alimentaryconstitutional obesity (Fedorov-Volodkin’s index, Green-Vermillion index, Sillness-Loe index, CPITN index) signifi cantly deteriorate compared with the corresponding indicators in the control group of adolescents without AKO, indicating the effect of alimentary-constitutional obesity on the clinical course, the severity and severity of theinfl ammatory process and the feasibility of timely and effective pharmacotherapy.


1975 ◽  
Vol 85 (2) ◽  
pp. 193-204 ◽  
Author(s):  
K. R. Drew ◽  
J. T. Reid

SUMMARYForty-eight cross-bred wether lambs were used to measure the effects of severe feed restriction and realimentation on the body and carcass composition of immature sheep. Ten of the total number of sheep were used as an initial slaughter group, 12 were continuously fed (six at the ad libitum level of intake and six at 70% ad libitum), 26 were progressively underfed and 18 of them were realimented after a mean loss of about 25% empty body weight (EBW).Shrunk body weight (SBW = weight after an 18-h fast with access to water) was a good predictor of empty body weight (EBW = SBW minus gastro-intestinal contents) and the EBW of continuously growing sheep was a good predictor of body water, protein, fat, energy and ash, but it was not precise after realimentation, particularly in the early stages of refeeding. Restricted continuous supermaintenance feeding did not alter the body composition of the sheep from that of the sheep on the ad libitum intake at any given EBW except slightly to increase the carcass protein content.Although underfeeding to produce an EBW loss of 25% generally produced changes in the chemical body components which were similar to a reversal of normal growth, body fat did not decrease during the first half of the submaintenance feeding and did not increase during the first 2 weeks of realimentation. Under all circumstances percentage body fat was very closely related to percentage body water.Sheep realimented at 26 kg (after losing 25% EBW) contained, at 45 kg EBW, more bodywater and protein and less fat and energy than continuously-fed animals of the same EBW. The treatment effects were greater in the carcass and had little effect on the non-carcass EBW, with th e result that the refed sheep had 1800 g more water × protein in a carcass that weighed 700 g more than one from a normally grown sheep of the same EBW. The regression of calorific value of th e ash-free dry matter on body fat as a percentage of ash-free dry matter gave calorific values of body protein and fat as 5·652 and 9·342 kcal/g of ash-free dry matter, respectively.


1972 ◽  
Vol 56 (1) ◽  
pp. 49-55
Author(s):  
OSSI V. LINDQVIST ◽  
INGA SALMINEN ◽  
PAUL W. WINSTON

1. The water content of the cuticle of both desiccated and non-desiccated terrestrial isopods Porcellio scaber and Armadillidium vulgare was measured. The animals were desiccated for various times (up to 3 h) over silica gel and the mean water content of the cuticle was 54.0±0.78% for P. scaber and 52.7±1.11% for A. vulgare. There was no trend as regards the desiccation time, nor did the body weight affect the water content. 2. The water content of the cuticle remained virtually unchanged as long as the animal was alive in the desiccator. It dropped significantly after the animal had died after having lost some 30% of its body weight. 3. The cuticular water content of non-desiccated P. scaber tended to be slightly higher than that of desiccated ones. In A. vulgare no significant difference was observed between non-desiccated and desiccated specimens. 4. The water activity of the excised cuticle of the above two species and of Oniscus asellus and Cylisticus convexus was above that of the haemolymph and therefore not in osmotic equilibrium with it. The osmotic equilibrium points were below the osmotic pressures of the blood; the difference amounted from 1.5 to 2.8 atm. in different species. 5. The difference in water activity between blood and cuticle, the maintenance of water content with desiccation, and the drop in water level at death, all indicate the presence of an active mechanism regulating the cuticular water in terrestrial isopods.


1927 ◽  
Vol 5 (1) ◽  
pp. 89-96
Author(s):  
J. BĚLEHRÁDEK ◽  
J. S. HUXLEY

(1) Injection of post-pituitary extract to larval and adult Amblystoma individuals leads to an increased water-intake, followed by a decrease in water-content the body, the decrease being greater than the preliminary increase. Repeated injections cause decreases of body-weight of over 35 per cent. (2) This effect runs parallel with the chromatophore effect. No change in oxygen consumption could be detected, even with long continued injection. (3) Both larval and metamorphosed Amblystoma lose weight (by loss of water) when narcotised in a solution of amytal 1 : 3000; the loss is greater in larval specimens; the decrease is followed, in metamorphosed animals, by a slight net increase. (4) Both the pituitary effect and the amytal effect develop considerably more quickly in larval than in metamorphosed Amblystoma. (5) The mechanism regulating the water-equilibrium of the body in Amblystoma passes, during metamorphosis, from a relatively imperfect state in the larval stage to a more efficient condition in adult individuals.


Sign in / Sign up

Export Citation Format

Share Document