Water Content and Water Activity in the Cuticle of Terrestrial Isopods

1972 ◽  
Vol 56 (1) ◽  
pp. 49-55
Author(s):  
OSSI V. LINDQVIST ◽  
INGA SALMINEN ◽  
PAUL W. WINSTON
Keyword(s):  
Body Weight ◽  
Water Content ◽  
Water Activity ◽  
Equilibrium Points ◽  
The Body ◽  
Porcellio Scaber ◽  
Terrestrial Isopods ◽  
Osmotic Equilibrium ◽  
Significant Difference ◽  
The Difference

1. The water content of the cuticle of both desiccated and non-desiccated terrestrial isopods Porcellio scaber and Armadillidium vulgare was measured. The animals were desiccated for various times (up to 3 h) over silica gel and the mean water content of the cuticle was 54.0±0.78% for P. scaber and 52.7±1.11% for A. vulgare. There was no trend as regards the desiccation time, nor did the body weight affect the water content. 2. The water content of the cuticle remained virtually unchanged as long as the animal was alive in the desiccator. It dropped significantly after the animal had died after having lost some 30% of its body weight. 3. The cuticular water content of non-desiccated P. scaber tended to be slightly higher than that of desiccated ones. In A. vulgare no significant difference was observed between non-desiccated and desiccated specimens. 4. The water activity of the excised cuticle of the above two species and of Oniscus asellus and Cylisticus convexus was above that of the haemolymph and therefore not in osmotic equilibrium with it. The osmotic equilibrium points were below the osmotic pressures of the blood; the difference amounted from 1.5 to 2.8 atm. in different species. 5. The difference in water activity between blood and cuticle, the maintenance of water content with desiccation, and the drop in water level at death, all indicate the presence of an active mechanism regulating the cuticular water in terrestrial isopods.

scholarly journals The Associations Between the Anorexic Readiness Syndrome, Familism, and Body Image Among Physically Active Girls

2022 ◽  
Vol 12 ◽  
Author(s):  
Beata Ziółkowska ◽  
Jarosław Ocalewski ◽  
Aleksandra Da̧browska
Keyword(s):  
Physical Activity ◽  
Body Image ◽  
Body Weight ◽  
Weight Control ◽  
Ideal Body Weight ◽  
The Body ◽  
Healthy Weight ◽  
Physically Active ◽  
Significant Difference ◽  
The Difference

Introduction:Anorexic Readiness Syndrome (ARS) is a construct of prophylactic importance, useful in the selection of people showing a tendency to use restrictive diets and increased concentration on the body. The aim of the research was to verify the significance of the type of physical activity, body perception and familism for the development of ARS.Material and Method: The research was carried out in the first half of 2021on a sample of 163 girls. It consisted of: (1) physically inactive girls (n = 48), (2) physically active girls in disciplines other than aesthetic (n = 69), (3) girls engaged in aesthetic physical activity (n = 46). The study used: Anorexic Readiness Syndrome Questionnaire (ARS-12), Familism Scale (FS) and Body Image Avoidance Questionnaire (BIAQ).Results: The highest average ARS score was recorded in the group of girls engaged in aesthetic activity. A significant difference in the severity of ARS occurs between people who do not engage in activity and those who practice aesthetic activity. The severity of ARS rises as the difference between real and ideal body weight increases. People active in aesthetic disciplines who obtained a high score on the Respect scale (FS subscale) have a lower ARS score than those physically active in other disciplines who obtained low scores on the Respect scale. The higher the score on the Material success and achievement scale (FS), the greater the ARS intensity in all subgroups. What is much more important in shaping ARS is the perception of your body. The focus on eating and body weight and Clothing and appearance (BIAQ subscales) are relevant to the ARS and moderate the relationship between Material success (FS subscale) and anorexic readiness.Conclusions: People engaging in aesthetic physical activity are more likely to suffer from ARS. The family can certainly prevent a child from developing anorexic readiness by shaping a sense of community and family identity, a clear division of roles, limiting the importance of materialism and competition in raising children. The prevention of ARS and eating disorders should also focus on strengthening the realistic assessment of body parameters and their acceptance, as well as promoting strategies for healthy weight control.

Perbedaan Penggunaan Antikoagulan K2EDTA DAN K3EDTA Terhadap Hasil Pemeriksaan Indeks Eritrosit

2018 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Wahdaniah Wahdaniah ◽  
Sri Tumpuk
Keyword(s):  
Screening Test ◽  
Venous Blood ◽  
The Body ◽  
Ethylene Diamine ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
Ethylene Diamine Tetra Acetate ◽  
The Difference ◽  
Index Value

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk  K2EDTA dan  K3EDTA. K3EDTA  biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.

Specific Susceptibility to HCN and the amount of HCN recovered from Fumigated Insects

1951 ◽  
Vol 42 (2) ◽  
pp. 399-418 ◽  
Author(s):  
S. Pradhan ◽  
S. C. Bhatia
Keyword(s):  
Body Weight ◽  
Water Content ◽  
Relative Position ◽  
Surface Resistance ◽  
Internal Resistance ◽  
Effective Resistance ◽  
The Body ◽  
Effective Dosage ◽  
Adult Females ◽  
The Dead

The relationship was studied between susceptibility of a number of different species of insects to HCN fumigation and the recovery of HCN from them immediately after fumigation.The test insects used were Tribolium castaneum, seventh stage caterpillars of Corcyra cephalonica, first-and second-instar nymphs of Drosicha sp., third-and fourthinstar nymphs of Drosicha sp. and adult females of Drosicha sp.The apparatus and methods used in the fumigation and in the recovery of HCN from the fumigated insects are fully described.Preliminary expsriments showed that the processes of distillation and redistillation did not affect the recovery of HCN but that the result obtained for recovery from distillation could be affected if some volatile reducing substance were produced and carried over to the distillate. It was found that this did actually take place in the case of one of the test insects—T. castaneum—but that redistillation got rid of the impurity.In the main experiments it was shown that, on the assumption that the concentration of HCN to which insects are exposed is the effective dosage, the susceptibility of the test insects varied in the following descending order : firstand second-stage nymphs of Drosicha sp. > third- and fourth-stage nymphs of Drosicha sp.>C. cephalonica> T. castaneum>the adult females of Drosicha sp.When the same insects were arranged in descending order of the quantities of HCN recovered per 100 gm. of body weight, the order was identical except for the nymphs of Drosicha sp. which occupied a different relative position. The two categories of nymphs of Drosicha sp. were found to occupy a different relative position again with regard to the other three test insects when exposed to a superlethal concentration and assessed for recovery of HCN per 100 gr. body weight.Parallel batches of T. castaneum and C. cephalonica were fumigated and the HCN was recovered from the dead and survivors. More HCN was recovered from the dead insects than from those that survived.Both recovery and sorption of HCN were estimated separately in parallel batches of insects (adult females of Drosicha sp. and C. cephalonica). Recovery was found to be less than sorption showing that a part of the HCN absorbed is converted into a non-recoverable state. Further, that the weight of HCN sorbed per gram body weight of adult females of Drosicha sp. is much less than in the case of C. cephalonica under similar conditions of fumigation and that the amount of HCN converted into non-recoverable products is less in Drosicha adults than in C. cephalonica.A comparison of the water content of T. castaneum, C. cephalonica and Drosicha sp. (adults) showed that there was a positive correlation between water content and higher susceptibility to HCN and greater recovery of HCN was also indicated. It is suggested that this may be a factor in the “ Surface Resistance ” of an insec to a fumigant.The observations of previous workers that larger amounts are sorbed by or recovered (after fumigation) from more susceptible species than for those less susceptible was corroborated by the results obtained with C. cephalonica, T. castaneum and adult females of Drosicha sp. but not with those from nymphs of Drosicha sp.When dosage-mortality graphs were prepared by taking the amount of HCN recovered per gram body weight as an index of internal dose, the order of resistance of different test insects based on this new criterion was found to be entirely different from that based on the usual criterion of the concentration of HCN in the fumatorium being the index of effective dosage.These apparently anomalous observations may be explained by assuming that the resistance shown by an insect in an actual fumigation operation, i.e., to the concentration of HCN to which it is exposed (external dose) is what may be called the total “ Effective Resistance ” and that this “ Effective Resistance ” is the resultant of (a) “ Surface Resistance ” to the entry of fumigant and (b) “ Internal Resistance ” to the amount of HCN which actually gains entry into the body in some way or other. Thus the “Effective Resistance ” of an insect may be due to a combination either of low “ Surface Resistance ” and high “ Internal Resistance ”, giving a very low “ Effective Resistance ” as in the case of C. cephalonica, or vice versa giving the maximum “ Effective Resistance ” as in adult females of Drosicha sp. The lower recovery of HCN from the nymphs of Drosicha sp., although they were more susceptible to fumigation than C. cephalonica, is explained by their higher “ Surface Resistance ” combined with a very much lower “ Internal Resistance ”, leading to a lower “ Effective Resistance ”.

A study on the safety evaluation of buphrenorphine administered through an autoinjector compared with manual injection using haematological and biochemical variables in rats

2016 ◽  
Vol 36 (9) ◽  
pp. 901-909 ◽  
Author(s):  
D Sheela ◽  
R Vijayaraghavan ◽  
S Senthilkumar
Keyword(s):  
Body Weight ◽  
Research Work ◽  
Safety Evaluation ◽  
Weight Ratio ◽  
The Body ◽  
Control Group ◽  
Body Weight Ratio ◽  
Significant Difference ◽  
Manual Group ◽  
Significant Change

Buprenorphine drug cartridge was made for autoinjector device for use in emergency and critical situations to reduce the morbidity and mortality. Water-filled cartridges were prepared and buprenorphine was injected aseptically in the cartridge, to make 0.05 and 0.10 mg/mL. Rats were injected intraperitoneally, buprenorphine (0.3 and 0.6 mg/kg), repeatedly with the autoinjector and compared with manual injection (7 days and 14 days) using various haematological and biochemical parameters. No significant change was observed in the body weight, organ to body weight ratio and haematological variables in any of the experimental groups compared with the control group. Except serum urea and aspartate aminotransferase, no significant change was observed in glucose, cholesterol, triglycerides, bilirubin, protein, albumin, creatinine, uric acid, alanine aminotransferase, gamma glutamyltransferase and alkaline phosphatase. The autoinjectors deliver the drugs with spray effect and force for faster absorption. In the present study, the autoinjector meant for intramuscular injection was injected intraperitoneally in rats, and the drug was delivered with force on the vital organs. No significant difference was observed in the autoinjector group compared to the manual group showing tolerability and safety of the buphrenorphine autoinjector. This study shows that buprenorphine autoinjector can be considered for further research work.

scholarly journals Morphometric characteristics of the patellar tendon

2016 ◽  
Vol 69 (suppl. 1) ◽  
pp. 53-58
Author(s):  
Milodrag Vranjes ◽  
Ivan Vukasinovic ◽  
Mirko Obradovic ◽  
Mile Bjelobrk ◽  
Zlatko Budinski ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Body Weight ◽  
Body Mass ◽  
Patellar Tendon ◽  
Cruciate Ligament ◽  
The Body ◽  
Professional Athletes ◽  
Morphometric Characteristics ◽  
Significant Difference ◽  
Anterior Cruciate

Introduction. The most common injuries of the knee joint are injuries of the anterior cruciate ligament. The golden standard in reconstruction of this ligament is graft bone - patellar tendon - bone. Knowing the morphometric characteristics of these ligaments is crucial for anterior cruciate ligament reconstruction. This study was aimed at determining morphometric characteristics of the patellar tendon in vivo, measured intraoperatively, and at defining the correlation between the obtained values and body weight, height, gender and sport activity among different groups of athletes. Material and Methods. This study included 184 patients suffering from anterior cruciate ligament injuries who were admitted to the Clinical Center of Vojvodina, Department of Orthopedics and Traumatology. Results. The patellar tendon width ranged from 28 mm to 43 mm, averaging at 32.02 mm. The length of the patellar tendon ranged from 35 mm to 62 mm, averaging at 46.34 mm. The thickness of the patellar tendon ranged from 3 mm to 6 mm, averaging at 3.78 mm. The measured results were positively and statistically relevant with the body mass, height and body mass index. Discussion and Conclusion. The patellar tendon was thicker, longer and wider in persons with higher values of body weight and height. Men have statistically longer, thicker and wider patellar tendon than women. There was no statistically significant difference between morphometric characteristics of the patellar tendon among professional athletes and recreational athletes, neither was there one in the obtained geometric data of the patellar tendon among tested groups of professional athletes.

scholarly journals Comparison between Vinorelbine–Carboplatin and Vinorelbine–Cisplatin in Stage III–IV EGFR Mutations-Negative NSCLC

2021 ◽  
Author(s):  
Laksmi Wulandari ◽  
Gatot Soegiarto ◽  
Anna Febriani ◽  
Farah Fatmawati ◽  
Wirya Sastra Amran
Keyword(s):  
Lung Cancer ◽  
Body Weight ◽  
Evaluation Criteria ◽  
Growth Factor Receptor ◽  
The Body ◽  
Stage Iii ◽  
Egfr Mutations ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Abstract Introduction There are a substantial number of lung cancer patients with negative mutations in Indonesia. This type of cancer is deemed to be the major contributor of lung cancer patient’s death. However, reseaerch related to therapy using vinorelbine combined with platinum-based compounds is still scarce in Indonesia. The aim of this study was to compare the efficacy and tolerability between vinorelbine and carboplatin with vinorelbin and cisplatin in stage III-IV epidermal growth factor receptor (EGFR) mutations-negative non-small cell lung cancer (NSCLC). Methods The participants were divided into two groups—group I(vinorelbine–carboplatin) and group II (vinorelbine–cisplatin). The participants were assessed based on several measurement criteria. Not only Eq-5D was performed, but the body weight and response evaluation criteria for solid tumors (RECIST) were also examined. The participants received chemotherapy for four cycles (1 cycle = 21 days). Results The quality of life was considered stable in 60% of group I and 60% of group II (p=0.255). In both groups, 46.67% of participants had an increased body weight, while the other 20.00% was stable (p = 1.000). In terms of RECIST evaluation after the second cycle, 80.00% of group I and 86.67% of group II were considered to have a stable disease, with 20% of group I and none of group II had partial response (p = 0.027). However, after the fourth cycle, there were no significant difference between the groups (p = 0.734). Conclusion In EGFR mutation-negative NSCLC patients, the combination of vinorelbine and carboplatin showed comparable outcomes to vinorelbine and cisplatin chemotherapy with no significant differences.

scholarly journals The difference in pediatric blood pressure between middle childhood and late childhood prior to dental treatment

2018 ◽  
Vol 25 (1) ◽  
Author(s):  
Fitri Anissa Syaimima Syaiful Azim ◽  
Arlette Suzy Puspa Pertiwi ◽  
Rosiliwati Wihardja
Keyword(s):  
Blood Pressure ◽  
Middle Childhood ◽  
Dental Treatment ◽  
Systolic Pressure ◽  
The Body ◽  
Late Childhood ◽  
Test Analysis ◽  
Mean Values ◽  
Significant Difference ◽  
The Difference

Every child will go through several stages in his or her life. They are different from each other as they are in the process of development of cognition, physics, emotion, and personality. For many children, a visit to the dentist can raise their anxiety. This anxiousness will lead to stress that influences the cardiovascular function in the body. The purpose of this research was to determine the difference in pediatric blood pressure between middle childhood and late childhood prior to dental treatment. This research was a clinical trial, pure experimental study. The sample consisted of 30 children within the range of 4-12 years old where they were divided into two groups of age; middle childhood (4-7 years old) and late childhood (8-12 years old). The blood pressures were measured before any dental treatment began and the values were recorded. The data were then analyzed using the One-Sample T-Test analysis. The results of blood pressure in middle childhood and late childhood were compared to the average mean values for each age group. It showed that there was a significant difference in the systolic pressure, which was found higher in the middle childhood group compared to the late childhood. From the result can be concluded that there was a difference in the pediatric blood pressure between middle childhood and late childhood prior to dental treatment.

scholarly journals Penggunaan Hasil Fermentasi Bungkil Kedelai Dalam Ransum Terhadap Pertumbuhan Ayam Pedaging

2001 ◽  
Vol 2 (2) ◽  
pp. 26-31
Author(s):  
Al Qudri
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Soybean Oil ◽  
Energy Content ◽  
Body Weight Gain ◽  
The Body ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Fermented Soybean ◽  
Significant Difference

ABSTRACT. Tempe of soybean is fermented soybean with Rhizopus ologosporus fungus. From a result of researchers, it is the fact that tempe can increase valuable of nutrion and digest capacity and also produce antibiotic . Utilization of abtibiotic in chiken food as stimulus growth in not recommended because it can cause resistance a certain germ and it is presume there are antibiotic residu in egg and chiken meat. It is hope that the use of fermented soybean oil meal can increase nutrient value and digest capacity as well as produce antibiotic, so that it can get a better growth and over come a problem of using antibiotic in chiken food. The study was conducted to evaluate the effect of fermented soybean oil meal utilization in the ration on body weight gain, feed consumption, feed conversion and mortality. The study use 80 unsex day old chick broiler CP-707 and conducted at Poulty Laboratory Product Agriculture Faculty, Syiah Kuala University. Chiken were putting in 27 houses unit, each unit contain of four chiken. The design of experiment was Completely Randomized Design, four treatments and five replication. The treatments were ration contained 0%, 5%, 10% and 15% fermented soybean oil meal as replace the use of soybean oil meal. The protein and energy content of all dietary treatments were equally composed from six weeks investigation, were body weight gain, feed consumption, feed conversion and mortality. The result of the study indicated that up to 10% graded of fermented soybean oil meal in ration were significant difference influenced increase the body weight gain and decrease the feed conversion. The fermented soybeanoil meal) utilization more than 10% were significant difference decrease the body weight gain and increase the feed conversion. If the inclusion was increase the feed consumption would tendency decline. In this study there were no mortality in all treatment. In can be advised from this study that fermented soybean oil meal could be used in broiler ration or in all poulty ration.

scholarly journals The effect of red-fleshed pitaya (Hylocereus polyrhizus) on heat shock protein 70 and cortisol expression in strenuous exercise induced rats

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 130
Author(s):  
Novita Sari Harahap ◽  
Aznan Lelo ◽  
Ambrosius Purba ◽  
Awaluddin Sibuea ◽  
Rina Amelia ◽  
...  
Keyword(s):  
Body Weight ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 70 ◽  
The Body ◽  
Male Rats ◽  
Strenuous Exercise ◽  
Hsp70 Expression ◽  
Average Weight ◽  
Significant Difference

Background: Oxidative stress from exercise can contribute to damaging cells, increasing heat shock protein 70 (HSP70) and suppressing the immune system in the body. This research aimed to determine the antioxidant potential of red-fleshed pitaya extract on HSP70 and cortisol expression in rats which were subjected to strenuous exercise. Methods: The subjects of this research were 32 Sprague Dawley male rats, aged 3 months, with an average weight of 200 g. Red-fleshed pitaya extract was obtained from methanol extraction process; a maceration technique was performed and the extract was concentrated using an air-drying method. Rats were randomly divided into four groups. Group 1 were subjected to strenuous exercise and treated with distilled water only; while Groups 2, 3 and 4 were subjected to strenuous exercise and treated with 100 mg/kg body weight, 200 mg/kg body weight and 300 mg/kg body weight of red-fleshed pitaya extract, respectively. Strenuous exercises in rats was performed by intense swimming of 20 min/day, 3 days a week for 3 weeks. HSP70 expression and cortisol were measured with Enzyme-Linked Immune Sorbent Assay (ELISA) method. Results: There was a significant reduction of HSP70 (p=0.000) and cortisol expression (p=0.000) between the groups. Also, there was a significant difference in the average decreasing of HSP70 expression between group 4 and either groups 1 or 2 (p=0.000). However, a significant difference between groups 4 and 3 was not observed (p=0.813). Lastly, a significant difference was found in the average decrease of cortisol expression between groups 4 and 1 (p=0.000), 2 (p=0.000), and 3 (p=0.000) respectively. Conclusion: Red-fleshed pitaya is potential to be utilized as antioxidant to decrease the HSP70 and cortisol expression.

scholarly journals Aberrant Lighting Causes Anxiety-like Behavior in Mice but Curcumin Ameliorates the Symptoms

Animals ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2590
Author(s):  
Dhondup Namgyal ◽  
Kumari Chandan ◽  
Sher Ali ◽  
Ajaz Ahmad ◽  
Maha J. Hashim ◽  
...  
Keyword(s):  
Body Weight ◽  
Research Field ◽  
The Body ◽  
Laboratory Animals ◽  
Artificial Lighting ◽  
Lighting Conditions ◽  
Daily Food ◽  
Significant Difference ◽  
Negative Effect ◽  
Lighting Systems

In the modern research field, laboratory animals are constantly kept under artificial lighting conditions. However, recent studies have shown the effect of artificial light on animal behavior and metabolism. In the present study on mice, following three weeks of housing in dim light at night (dLAN; 5lux) and complete darkness (DD; 0lux), we monitored the effect on body weight, daily food intake, anxiety-like behavior by employing the open field test, and expression of the period (PER1) gene. We also studied the effect of oral administration of different concentrations of curcumin (50, 100, and 150 mg/kg) for three weeks in the same mice and monitored these parameters. The exposure to dLAN had significantly increased the anxiety-like behavior and body weight possibly through the altered metabolism in mice, whereas exposure to DD caused increased anxiety but no significant difference in weight gain. Moreover, the expression of the PER1 gene involved in sleep was also found to be decreased in the aberrant light conditions (dLAN and DD). Although the treatment of curcumin had no effect on body weight, it ameliorated the anxiety-like behavior possibly by modulating the expression of the PER1 gene. Thus, alteration in the light/dark cycle had a negative effect on laboratory animals on the body weight and emotions of animals. The present study identifies the risk factors associated with artificial lighting systems on the behavior of laboratory animals and the ameliorative effects of curcumin, with a focus on anxiety-like behavior.

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