A SYNTHESIS OF α-NAPHTHYL-ACETIC ACID AND SOME HOMOLOGUES

1939 ◽  
Vol 17b (1) ◽  
pp. 14-20 ◽  
Author(s):  
Richard H. F. Manske ◽  
Archie E. Ledingham
Keyword(s):  
Acetic Acid ◽  
Methyl Ether ◽  
Valeric Acid ◽  
Diacetic Acid ◽  
Standard Procedures ◽  
Crude Product ◽  
By Products

In the course of a study of the synthesis of α-naphthyl-acetic acid, a method was elaborated by Dr. A. Cambron that made available large quantities of α-chloromethyl-naphthalene. During the purification of the crude product and in the later stages of the synthesis we have encountered a number of by-products. Among others, these include methyl α-naphthyl-methyl ether, di-α-naphthyl-methyl ether, α-naphthyl carbinol, and 1:5-bis-chloromethyl-naphthalene. The last-named was converted into 1:5-naphthylene-diacetic acid, m.p. 280 °C., via the corresponding nitrile. δ-(1-Naphthyl)-valeric acid, m.p. 84 °C., and ε-(1-naphthyl)-hexoic acid, m.p. 62 °C., were synthesized by standard procedures.

scholarly journals On the asymptotic stability of advection-diffusion equations of mass transport in a bubble column bioreactor

2021 ◽  
Vol 2090 (1) ◽  
pp. 012035
Author(s):  
Paola Lecca ◽  
Angela Re
Keyword(s):  
Acetic Acid ◽  
Control System ◽  
Asymptotic Stability ◽  
Bubble Column ◽  
Bubble Column Reactor ◽  
Dissolved Gas ◽  
Advection Diffusion Equation ◽  
Bubble Column Bioreactor ◽  
Advection Diffusion ◽  
By Products

Abstract This study presents an asymptotic stability analysis of a model of a bioreactor converting carbon monoxide (CO) gas into ethanol through a C. autoethanogenum biocatalyst. The configuration is a bubble column reactor with co-current gas-liquid flows where gas feed is introduced by a gas distributor placed at the bottom of the column. A pure culture of C. autoethanogenum is subsequently injected at the bottom of the column; therein, cells are dispersed in the liquid and consume the dissolved gas and release by-products such as ethanol and acetic acid. Cellular growth and byproduct secretion are affected by spatially varying dissolved gas concentrations due to advection-diffusion mass transports which are induced by the effect of the injection pressure and gravitational force. The model accounts for four species representing the biomass, the CO substrate in the liquid phase, and two by-products - ethanol and acetic acid. Substrate dynamics is described by an advection-diffusion equation. We investigate the asymptotic stability of the biomass dynamics that is a requirement for the system’s controllability, i.e. for the possibility to steer a dynamical system from an arbitrary initial state to an arbitrary final state using a set of controls. The concept of stability of the controls is extremely relevant to controllability since almost every workable control system is designed to be stable. If a control system is not stable, it is usually of no use in practice in industrial processes. In the case of a bioreactor, the control is the biomass and controllability is the possibility of modulating through this control the ethanol production. We present a test for asymptotic stability, based on the analysis of the properties of the dynamic function defining its role as storage function.

scholarly journals Eine neue Methode zur Herstellung und Reinigung von 5-Methyltetrahydrofolsäure / A New Method for Preparation and Purification of 5-M ethyltetrahydrofolic Acid

1973 ◽  
Vol 28 (11-12) ◽  
pp. 650-652
Author(s):  
Harold Rüdiger ◽  
Reinhard Siede
Keyword(s):  
Acetic Acid ◽  
Folic Acid ◽  
Ion Exchange ◽  
Sodium Borohydride ◽  
Sodium Salt ◽  
Barium Salt ◽  
Borohydride Reduction ◽  
Methyl Derivative ◽  
Crude Product ◽  
Sodium Borohydride Reduction

Abstract 5-Methyltetrahydrofolic acid is prepared from folic acid by sodium borohydride reduction, reac­ tion with formaldehyde and reduction to the methyl derivative by sodium borohydride. The crude product is precipitated as barium salt which after having been converted to the sodium salt by ion exchange is adsorbed to QAE-Sephadex and eluted by different acetic acid gradients in subsequent chromatographies. This method allows to process gram quantities on reasonably small columns

Organically Modified Silica-Based Xerogels Derived from 3-Aminopropyltrimethoxysilane and 3-Isocyanatepropyltriethoxysilane through Carboxylic Acid Solvolysis

2006 ◽  
Vol 514-516 ◽  
pp. 108-112 ◽  
Author(s):  
Lianshe Fu ◽  
Rute A. Sá Ferreira ◽  
Sonia S. Nobre ◽  
Luís D. Carlos ◽  
João Rocha
Keyword(s):  
Acetic Acid ◽  
Carboxylic Acid ◽  
Valeric Acid ◽  
Silica Xerogels ◽  
X Ray Diffraction ◽  
Modified Silica ◽  
13C Nuclear Magnetic Resonance ◽  
Organically Modified ◽  
Cross Links ◽  
Organically Modified Silica

Organically-modified silica xerogels from 3-aminopropyltrimethoxysilane (APTES) and 3-isocyanatepropyltriethoxysilane (ICPTES) have been synthesized through carboxylic acid (formic acid, acetic acid and valeric acid) solvolysis. The resulting hybrid materials have been characterized by powder X-ray diffraction, mid-infrared spectroscopy, 29Si and 13C nuclear magnetic resonance, and photoluminescence spectroscopy. The results show that urea cross-links have been formed in these hybrids. The luminescence features depend on the selected carboxylic acids. For example, comparatively to the hybrids derived from formic and acetic acid solvolysis, valeric acid shows a red-shift of the emission features.

scholarly journals Increasing of Food and Bioenergy Potato Resources by Microbial Influence on Tubers Phytohormonal Status

2014 ◽  
Vol 14 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Elena I. Kiprushkina ◽  
Denis A. Baranenko
Keyword(s):  
Acetic Acid ◽  
Bacillus Subtilis ◽  
Potato Yield ◽  
Potato Tubers ◽  
Yield Increase ◽  
Physiological Dormancy ◽  
Indole 3 Acetic Acid ◽  
By Products ◽  
Control Samples

Abstract Potato and its by-products became a promising both food and bioenergy resource. The determination of the bacteriaantagonists influence on phytohormone status and productivity of potato tubers was studied. The indole-3-acetic acid content during the dormancy end and germinating in the tubers treated with Bacillus subtilis Ch-13 was fewer than in the control samples. L-tryptophan significant quantity compared to the control was found in the treated tubers in a state of physiological dormancy (more than 2-fold) and especially during active germination (43 times greater). Average potato yield increase at treated fields was of 18.8 %.

257. The influence of various factors on the fermentation end-products of the heterofermentative lactobacilli

1940 ◽  
Vol 11 (2) ◽  
pp. 136-144 ◽  
Author(s):  
C. C. Thiel
Keyword(s):  
Acetic Acid ◽  
Lactic Acid ◽  
Growth Factors ◽  
Oxygen Tension ◽  
Alcoholic Fermentation ◽  
Total Production ◽  
Anaerobic Conditions ◽  
Yeast Autolysate ◽  
Relative Production ◽  
By Products

1. The influence of temperature, oxygen tension, yeast autolysate and chalk on the production of by-products and the ratios of by-products formed to sugar utilized and lactic acid produced in milk by the lactobacilli has been investigated.2. The total production of lactic acid is increased by the presence of chalk and “growth factors” but is not affected by temperature or oxygen tension. The ratio of lactic acid produced to sugar utilized is decreased at lower temperatures and increased by chalk but yeast autolysate and variation in oxygen tension give variable results.3. The total production of acetic acid is increased by the presence of chalk, and “growth factors” and by anaerobic conditions. The ratios of acetic acid produced to sugar utilized and lactic acid formed are decreased by chalk and anaerobic conditions and there is a tendency for the ratios to be decreased by the presence of yeast and increased at lower temperatures.4. The total production of alcohol is increased by anaerobiosis and also by the presence of chalk and yeast in the medium. The ratios of alcohol formed to sugar utilized and lactic acid produced is increased by anaerobic conditions, and chalk also tends to increase the relative amount of alcohol. Temperature and yeast autolysate have little effect.5. Chalk is effective in maintaining thepH at a higher level during growth, but the influence of chalk on the ratios of by-products formed to sugar utilized is probably not entirely a pS. effect since the addition of talc to the medium has an equally strong influence in altering the relative production of lactic acid and alcohol.6. It was previously shown for the heterofermentative streptococci that the Pasteur effect (suppression of alcoholic fermentation by respiration) is slight; similar results have been obtained with the heterofermentative lactobacilli.

An efficient synthesis of pterosin C and other pterosins

1984 ◽  
Vol 62 (10) ◽  
pp. 1945-1953 ◽  
Author(s):  
Kam-Mui Eva Ng ◽  
Trevor C. McMorris
Keyword(s):  
Acetic Acid ◽  
Acetic Anhydride ◽  
Methyl Ether ◽  
Sodium Acetate ◽  
Synthetic Route ◽  
Efficient Synthesis ◽  
Trans Isomers ◽  
Cis And Trans Isomers ◽  
Cis And Trans

A versatile synthetic route to pterosins, sesquiterpenoid indanones present in bracken, Pteridiumaquilinum, has been developed. The route is exemplified by the synthesis of (2S,3S)-pterosin C by Friedel–Crafts bisacylation of the methyl ether of 2-(2,6-dimethylphenyl)ethanol with methylmalonyl chloride. Demethylation of the resulting 1,3-indandione and reduction with zinc and acetic acid in the presence of acetic anhydride and sodium acetate afforded a mixture of racemic cis and trans isomers of pterosin C diacetate, which was hydrolysed to the corresponding pterosins. Separation and resolution via the S-(+)-α-phenylbutyric esters gave (2S,3S)-pterosin C and (2R,3R)-pterosin C. Other pterosins were prepared as racemates from the 1,3-indandione.

scholarly journals Flavonoids and Triterpenoids from the Roots of Rosa laevigata

2017 ◽  
Vol 58 (4) ◽  
Author(s):  
Ning Li ◽  
Kaijin Wang ◽  
Shiping Li ◽  
Xiangyu Zhai ◽  
Tianming Wang ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Methyl Ether ◽  
Betulinic Acid ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Dpph Assay ◽  
Isolation And Identification ◽  
Phytochemical Investigation ◽  
Rosa Laevigata

<p>Phytochemical investigation on the root of <em>R. laevigata</em> led the isolation and identification of two new flavonoids, (+)-catechin-8-acetic acid (<strong>1</strong>) and guibourtacacidine 4-methyl ether (<strong>2</strong>), one known flavonoid, guibourtacacidine (<strong>3</strong>), along with seven known triterpenoids, euscaphic acid (<strong>4</strong>), kajiichigoside F1 (<strong>5</strong>), nigaichigoside F2 (<strong>6</strong>), rubuside J (<strong>7</strong>), tomentic acid (<strong>8</strong>), rosamutin (<strong>9</strong>) and betulinic acid (<strong>10</strong>). Their structures were established on the basis of spectroscopic evidence and comparisons with literature data. Compounds <strong>1</strong>, <strong>2</strong> and <strong>3</strong> showed considerable radical scavenging activity in the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay.<strong></strong></p>

scholarly journals 10a,11,11-Trimethyl-10a,11-dihydro-8H-benzo[e]imidazo[1,2-a]indol-9(10H)-one

2017 ◽  
Author(s):  
Elena Ščerbetkaitė ◽  
Rasa Tamulienė ◽  
Aurimas Bieliauskas ◽  
Algirdas Šačkus
Keyword(s):  
Optical Properties ◽  
Acetic Acid ◽  
Nmr Spectroscopy ◽  
Fluorescence Spectroscopy ◽  
Subsequent Treatment ◽  
15N Nmr ◽  
Crude Product ◽  
15N Nmr Spectroscopy ◽  
Work Up

The alkylation of 1,1,2-trimethyl-1H-benzo[e]indole with 2-chloroacetamide, followed by work-up of the reaction mixture with a base and the subsequent treatment of a crude product with acetic acid gives 10a,11,11-trimethyl-10a,11-dihydro-8H-benzo[e]imidazo[1,2-a]indol-9(10H)-one. The structure assignments were based on data from 1H, 13C and 15N NMR spectroscopy. The optical properties of the obtained compound were studied by UV-vis and fluorescence spectroscopy.

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