THE CONCENTRATION AND ACCUMULATION OF LIPIDS IN THE TUMOR COMPONENT OF A TUMOR–HOST ORGANISM, WALKER CARCINOMA 256 IN ALBINO RATS

1952 ◽  
Vol 30 (3) ◽  
pp. 163-172
Author(s):  
Eldon M. Boyd ◽  
H. D. McEwen
Keyword(s):  
Life History ◽  
Lipid Analysis ◽  
Albino Rats ◽  
Host Organism ◽  
History Of ◽  
Marked Accumulation ◽  
High Concentrations ◽  
Walker Carcinoma ◽  
Accumulation Of Lipids ◽  
Host Component

A study was made of the lipid concentration and accumulation in the tumor component of a tumor–host organism at progressive intervals during its growth using Walker Carcinoma 256 in albino rats. At the end of each of 7, 14, 21, and 28 days of tumor growth, and covering the entire life history of Walker Carcinoma 256, 10 tumor–rat organisms were sacrificed and appropriate sections of the tumor removed for differential lipid analysis by oxidative micromethods. The outstanding feature revealed in these studies was the maintenance, throughout its life history, of high concentrations of phospholipid, free and esterified cholesterol in Walker Carcinoma 256, and the increasing accumulation of large amounts of these lipids in the tumor component of the tumor–host organism. There was no marked accumulation of neutral fat which, in the tumor, declined to almost l/10th its initial concentration concurrently with the visible loss of storage fat in the host component. A day or two before death, the central core of the tumor appeared necrotic, its concentration of phospholipid declined and its concentration of free cholesterol rose. Otherwise, the lipid composition of the tumor was uniform throughout the cross section.

On the Prophylactic Action of Vitamin A in Helminthiasis

1933 ◽  
Vol 11 (1) ◽  
pp. 9-24 ◽  
Author(s):  
Phyllis A. Clapham
Keyword(s):  
Life History ◽  
Vitamin A ◽  
Close Contact ◽  
Albino Rats ◽  
Parascaris Equorum ◽  
Rate Of Development ◽  
Vitamin Content ◽  
Introductory Part ◽  
History Of ◽  
Host Tissues

(1) Experiments have been conducted to investigate the part played by Vitamin A in the prophylaxis of helminthiasis. Heterakis gallinæ in the chicken and Parascaris equorum in albino rats were used.(2) The evidence tends to show that in Heterakis infestation the vitamin content of the diet has no effect on the course of the infestation. In Ascariasis in rats, however, the vitamin affects significantly the hatching, survival and rate of development of the larvae within the host.(3) The writer can put forward no reason for this difference except to suggest that it may lie in. the life history of the parasites. Considering her own results and those of previous workers as cited in the introductory part of this paper, it seems obvious that the vitamin is effective in cases where the parasite comes into close contact with the host tissues.(4) Some notes on the viability of eggs are added.

Experimental life history of Echinostoma cinetorchis

1990 ◽  
Vol 28 (1) ◽  
pp. 39 ◽  
Author(s):  
S H Lee ◽  
J Y Chai ◽  
S T Hong ◽  
W M Sohn
Keyword(s):  
Life History ◽  
History Of

Queering Gender Identity Work: A Life History of a Black Transgender Woman

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Esethu Monakali
Keyword(s):  
Life History ◽  
Gender Identity ◽  
Public Spaces ◽  
Identity Work ◽  
Social Identities ◽  
Gender And Sexuality ◽  
Ongoing Effort ◽  
History Of ◽  
The Individual

This article offers an analysis of the identity work of a black transgender woman through life history research. Identity work pertains to the ongoing effort of authoring oneself and positions the individual as the agent; not a passive recipient of identity scripts. The findings draw from three life history interviews. Using thematic analysis, the following themes emerge: institutionalisation of gender norms; gender and sexuality unintelligibility; transitioning and passing; and lastly, gender expression and public spaces. The discussion follows from a poststructuralist conception of identity, which frames identity as fluid and as being continually established. The study contends that identity work is a complex and fragmented process, which is shaped by other social identities. To that end, the study also acknowledges the role of collective agency in shaping gender identity.

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