Fabrication of a highly sensitive and selective electrochemical sensor based on chitosan-coated Fe3O4 magnetic nanoparticle for determination of antibiotic ciprofloxacin and its application in biological samples

2016 ◽  
Vol 94 (10) ◽  
pp. 803-811 ◽  
Author(s):  
Sara Dehdashtian ◽  
Mohammad Bagher Gholivand ◽  
Mojtaba Shamsipur ◽  
Azadeh Azadbakht ◽  
Ziba Karimi
Keyword(s):  
Magnetic Nanoparticle ◽  
Electrochemical Impedance ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Carbon Paste ◽  
Sensitive Sensor ◽  
Linear Differential ◽  
Fe3o4 Magnetic Nanoparticle

A simple and sensitive sensor has been developed for the electrochemical determination of ciprofloxacin (CF). The proposed sensor was designed by chitosan-coated Fe3O4 magnetic nanoparticle incorporated in the carbon paste electrode (CPE), which provides remarkably improved sensitivity for the electrochemical determination of CF. The proposed sensor was characterized with scanning electron microscopy and electrochemical impedance spectroscopy. Under optimum conditions, the sensor provides two linear differential pulse voltammetry responses in the range of 0.05–6 μmol/L and 6–75 μmol/L for CF with a detection limit of 0.01 μmol/L. The proposed sensor exhibited high sensitivity and good selectivity and was successfully applied for CF determination in serum and urine samples.

Preparation of yolk–shell structured Ag@Cu particles and their application in high performance electrochemical sensing of p-aminobenzoic acid

2019 ◽  
Vol 97 (2) ◽  
pp. 140-146
Author(s):  
Tian Gan ◽  
Zhikai Wang ◽  
Mengru Chen ◽  
Wanqiu Fu ◽  
Haibo Wang ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
High Performance ◽  
Electrochemical Impedance ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Electrochemical Sensing ◽  
High Catalytic Activity ◽  
Aminobenzoic Acid ◽  
Transmission Electron

In this work, the Ag@Cu particles with yolk–shell nanostructure was prepared by facile solvothermal method, which was modified on glassy carbon electrode (GCE) to fabricate electrochemical sensor for the convenient and fast determination of p-aminobenzoic acid (PABA). The surface morphology and electrochemical properties of the as-prepared Ag@Cu nanocomposite modified electrode were characterized by scanning electron microscopy, transmission electron microscopy, chronocoulometry, and electrochemical impedance spectroscopy. Further, the electrochemical sensing of PABA was performed on the Ag@Cu/GCE using cyclic voltammetry and differential pulse voltammetry techniques, showing high catalytic activity. Under the optimal conditions, the sensor exhibited a wide linear range, high sensitivity, and low detection limit of 0.315 μmol/L for PABA. The developed sensor was also successfully applied for PABA detection in anesthetic and cosmetics with satisfactory results.

Indirect Differential Pulse Voltammetric Determination of Fluoride Ions at Carbon Paste Electrode Modified with Porous and Electroactive Fe3+/Fe2+ Based-Metal Organic Frameworks Type MIL-101(Fe)

2021 ◽  
Author(s):  
Ashraf Mahmoud ◽  
Mater Mahnashi ◽  
Samer Abu-Alrub ◽  
Saad Kahatani ◽  
Mohamed El-Wekil
Keyword(s):  
Carbon Paste Electrode ◽  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Metal Organic Frameworks ◽  
Differential Pulse ◽  
Carbon Paste ◽  
X Ray ◽  
Metal Organic ◽  
Paste Electrode

Abstract An innovative and reliable electrochemical sensor was proposed for simple, sensitive and selective determination of F- ions. The sensor is based on the fabrication of porous and electroactive Fe-based metal organic frameworks [MIL-101(Fe)]. It was blended with graphite powder and liquid paraffin oil to from carbon paste electrode (CPE). The MIL-101(Fe)@CPE was characterized using different techniques such as scanning electron microscope, powder X-ray diffraction spectroscopy, Fourier transform infrared spectroscopy, energy dispersive X-ray, cyclic voltammetry, electrochemical impedance spectroscopy, differential pulse voltammetry. The MIL-101(Fe)@CPE exhibited two redox peaks (anodic and cathodic) corresponding to Fe3+ and Fe2+, respectively. The determination of F- ions based on the formation of a stable fluoroferric complex with Fe3+/ Fe2+, decreasing the currents of redox species. It was found that the anodic peak current (Ipa) is linearly proportional to the concentration of F- in the range of 0.67-130 µM with a limit of detection (S/N=3) of 0.201 µM. The electrode exhibited good selectivity towards F- detection with no significant interferences from common anions. The as-fabricated sensor was applied for the determination of F- in environmental water samples with recoveries % and RSDs % in the range of 98.1-102.4 % and 2.4-3.7 %, respectively.

scholarly journals A novel dopamine electrochemical sensor based on La3+/ZnO nanoflower modified graphite screen printed electrode

2019 ◽  
Vol 9 (3) ◽  
pp. 187-195 ◽  
Author(s):  
Somayeh Tajik ◽  
Hadi Beitollahi ◽  
Mohammad Reza Aflatoonian
Keyword(s):  
Modified Electrode ◽  
Phosphate Buffer Solution ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Screen Printed Electrode ◽  
Buffer Solution ◽  
Optimized Conditions ◽  
Screen Printed

Flower-like La3+/ZnO nanocomposite was facile synthesized. A simple and ultrasensitive sensor based on graphite screen printed electrode (SPE) modified by La3+/ZnO nanoflower was developed for the electrochemical determination of dopamine. The electrochemical behavior of dopamine was studied in 0.1 M phosphate buffer solution (PBS) using cyclic voltammetry (CV), chronoamperometry (CA) and differential pulse voltammetry (DPV). Compared with the unmodified graphite screen printed electrode, the modified electrode facilitates the electron transfer of dopamine, since it notably increases the oxidation peak current of dopamine. Also, according to CV results the maximum oxidation of dopamine on La3+/ZnO/SPE occurs at 150 mV which is about 140 mV more negative compared with unmodified SPE. Under optimized conditions, the modified electrode exhibited a linear response over the concentration range from 0.15 to 300.0 μM, with a detection limit of 0.08 μM (S/N = 3). The proposed sensor exhibited a high sensitivity, good stability and was successfully applied for dopamine determination in dopamine ampoule, with high recovery.

scholarly journals A New Sensitive Sensor for Simultaneous Differential Pulse Voltammetric Determination of Codeine and Acetaminophen Using a Hydroquinone Derivative and Multiwall Carbon Nanotubes Carbon Paste Electrode

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Elahe Garazhian ◽  
M. Reza Shishehbore
Keyword(s):  
Carbon Nanotubes ◽  
Differential Pulse Voltammetry ◽  
Multiwall Carbon Nanotubes ◽  
Differential Pulse ◽  
Carbon Paste ◽  
Sensitive Sensor ◽  
Pulse Voltammetry ◽  
Paste Electrode ◽  
Multiwall Carbon

A new sensitive sensor was fabricated for simultaneous determination of codeine and acetaminophen based on 4-hydroxy-2-(triphenylphosphonio)phenolate (HTP) and multiwall carbon nanotubes paste electrode at trace levels. The sensitivity of codeine determination was deeply affected by spiking multiwall carbon nanotubes and a modifier in carbon paste. Electron transfer coefficient,α, catalytic electron rate constant,k, and the exchange current density,j0, for oxidation of codeine at the HTP-MWCNT-CPE were calculated using cyclic voltammetry. The calibration curve was linear over the range 0.2–844.7 μM with two linear segments, and the detection limit of 0.063 μM of codeine was obtained using differential pulse voltammetry. The modified electrode was separated codeine and acetaminophen signals by differential pulse voltammetry. The modified electrode was applied for the determination of codeine and acetaminophen in biological and pharmaceutical samples with satisfactory results.

scholarly journals Differential pulse voltammetric determination of dopamine with the coexistence of ascorbic acid on boron-doped diamond surface

2007 ◽  
Vol 5 (4) ◽  
pp. 1114-1123 ◽  
Author(s):  
Zhao Guo-hua ◽  
Li Ming-fang ◽  
Li Ming-li
Keyword(s):  
Ascorbic Acid ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Diamond Surface ◽  
Boron Doped Diamond ◽  
Peak Separation ◽  
Boron Doped ◽  
Two Peaks

AbstractElectrochemical determination of dopamine (DA) in the presence of ascorbic acid (AA) was achieved on boron-doped diamond (BDD) film electrode by differential pulse voltammetry. The experimental results indicated that the oxidative peaks of DA and AA could be separated completely on anodically-treated (BDD) electrode without further modification, although these two peaks can not be separated on glassy carbon electrode. The peak separation of DA and AA was developed to be 0.44 V. High sensitivity was obtained to determine DA selectively with the coexisting of a large excess of AA in acidic media by DPV. The detection limit of DA was achieved to be 1.1 × 10-6 M in the presence of AA with the concentration of 200 times more than DA. This technique was also applied to the determination of DA in real samples.

A graphitic carbon nitride (g-C3N4/Fe3O4) nanocomposite: an efficient electrode material for the electrochemical determination of tramadol in human biological fluids

2019 ◽  
Vol 11 (15) ◽  
pp. 2064-2071 ◽  
Author(s):  
Morassa Hassannezhad ◽  
Morteza Hosseini ◽  
Mohammad Reza Ganjali ◽  
Majid Arvand
Keyword(s):  
Carbon Nitride ◽  
Biological Fluids ◽  
Electrochemical Determination ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride ◽  
Carbon Paste ◽  
Highly Sensitive ◽  
Sensitive Sensor ◽  
Paste Electrode

In the present study, a graphitic carbon nitride/Fe3O4 (g-C3N4/Fe3O4) nanocomposite/carbon paste electrode was used as a highly sensitive sensor for the voltammetric determination of tramadol (Tr) in an aqueous solution.

scholarly journals Differential pulse anodic stripping voltammetric determination of berberine using nano-Na-montmorillonite clay modifiedcarbon paste electrode

2013 ◽  
Vol 78 (4) ◽  
pp. 537-548 ◽  
Author(s):  
Wen Chen ◽  
Ming-Xiao Zhang ◽  
Cong Li ◽  
Yong-Ling Li
Keyword(s):  
Linear Sweep Voltammetry ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Modified Carbon Paste Electrode ◽  
Carbon Paste ◽  
Pharmaceutical Tablets ◽  
Anodic Stripping ◽  
Mmt Clay ◽  
Paste Electrode

A simple and sensitive method was presented to electrochemical determination of berberine based on the nano-Na-montmorillonite (nano-Na-MMT) clay modified carbon paste electrode. The electrochemical oxidation and adsorption behavior of berberine was studied at the proposed electrodeby linear sweep voltammetry in acetate buffer (0.2 M, pH 5.6). A differential pulse anodic stripping voltammetric procedure has been developed fordetermination of the drug. A good linear relationship between the oxidation peak current magnitude and the concentration of berberine was observed in the range from 1.0 to 18.0 ?gmL-1with detection limit of 0.07 ?gmL-1and quantitation limit of0.24 ?gmL-1. The proposed method was successfully applied to the determination of berberine in pharmaceutical tablets.

scholarly journals Electroanalytical Performance of a Carbon Paste Electrode Modified by Coffee Husks for the Quantification of Acetaminophen in Quality Control of Commercialized Pharmaceutical Tablets

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Serge Foukmeniok Mbokou ◽  
Maxime Pontié ◽  
Jean-Philippe Bouchara ◽  
Francis Merlin Melataguia Tchieno ◽  
Evangeline Njanja ◽  
...  
Keyword(s):  
Carbon Paste Electrode ◽  
Low Cost ◽  
Pharmaceutical Formulations ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Current Response ◽  
Carbon Paste ◽  
Pharmaceutical Tablets ◽  
Paste Electrode

Electrochemical determination of acetaminophen (APAP) was successfully performed using a carbon paste electrode (CPE) modified with coffee husks (CH-CPE). Scanning electron microscopy (SEM) and SEM-energy dispersive X-ray spectroscopy (SEM-EDX) were, respectively, used for the morphological and elemental characterization of coffee husks prior to their utilization. The electrochemical oxidation of APAP was investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV). SWV technique appeared to be more sensitive since the oxidation current of APAP was twofold higher with the CH-CPE sensor than with the bare CPE, in relation to the increase in the organophilic character of the electrode surface. Furthermore, on CH-CPE, the current response of APAP varied linearly with its concentration in the range of 6.6 μM to 0.5 mM, leading to a detection limit of 0.66 μM (S/N=3). Finally, the proposed CH-CPE sensor was successfully used to determine the amount of APAP in commercialized tablets (Doliprane® 500 and Doliprane 1000), with a recovery rate ranging from 98% to 103%. This novel sensor opens the way for the development of low-cost and reliable devices for the electroanalysis of pharmaceutical formulations in developing countries.

scholarly journals Development of a Carbon Paste Electrode Containing Benzo-15-Crown-5 for Trace Determination of the Uranyl Ion by Using a Voltammetric Technique

2009 ◽  
Vol 92 (1) ◽  
pp. 241-247 ◽  
Author(s):  
Sunil K Agrahari ◽  
Sangita D Kumar ◽  
Ashwini K Srivastava
Keyword(s):  
Detection Limit ◽  
Differential Pulse Voltammetry ◽  
Modified Electrode ◽  
Carbon Paste Electrode ◽  
Electrochemical Impedance ◽  
Differential Pulse ◽  
Carbon Paste ◽  
Pulse Voltammetry ◽  
Paste Electrode

Abstract The interaction of macrocyclic compounds like crown ethers and UO22+ has been studied by electrochemical methods. A modified carbon paste electrode incorporating benzo-15-crown-5 (B15C5) was used to evaluate the electron transfer reaction of UO22+ by cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. Electrochemical impedance studies showed that charge transfer resistance was less for the B15C5-modified electrode than for the plain carbon paste electrode (PCPE). On the basis of these observations, a UO22+-sensitive crown ether chemically modified electrode (CME) for trace analysis was fabricated and investigated in aqueous solutions. It was found that a 5 B15C5CME for UO22+ showed a better voltammetric response than did the PCPE. UO22+ could be quantified at sub-μg/mL levels by differential pulse voltammetry with a detection limit of 0.03 μg/mL. By differential pulse adsorptive stripping voltammetry, UO22+ could be quantified in the working range of 0.002-0.2 μg/mL, with a detection limit of 1.1 μg/L. Simultaneous determination of UO22+, Pb2+, and Cd2+ was possible. The method was successfully applied to the determination of UO22+ in synthetic, as well as real, samples; the results were found to be comparable to those obtained by inductively coupled plasma-atomic emission spectroscopy.

scholarly journals A novel carbon paste electrode based on nitrogen-doped hydrothermal carbon for electrochemical determination of carbendazim

2017 ◽  
Vol 82 (11) ◽  
pp. 1259-1272 ◽  
Author(s):  
Ana Kalijadis ◽  
Jelena Djordjevic ◽  
Zsigmond Papp ◽  
Bojan Jokic ◽  
Vuk Spasojevic ◽  
...  
Keyword(s):  
Carbon Paste Electrode ◽  
Low Cost ◽  
Nitrogen Concentration ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Carbon Paste ◽  
Nitrogen Doped ◽  
Cyclic Voltammetry Measurement ◽  
Paste Electrode

In this work, a new carbon paste electrode, prepared from nitrogen- -doped hydrothermal carbon (CHTCN) was applied for the electrochemical detection and determination of carbendazim fungicide. CHTCN samples with the nominal nitrogen content 0.05?0.5 wt. % in glucose precursor were prepared by simple, low-cost synthesis with the accompanying carbonization to 1273 K. The presence of nitrogen in CHTCN samples was confirmed by elemental analysis. Characterization of CHTCN as material for carbon paste electrode was achieved by cyclic voltammetry measurement of the Fe(CN)6 3-/4- redox couple. The results showed that best electrochemical response was obtained from the sample with a nominal nitrogen concentration of 0.1 wt. % and with tricresyl phosphate as a binder. During the development of a differential pulse stripping voltammetric method for carbendazim determination applying new electrode, the following experimental parameters were studied: the sort and amount of binding liquid, the effect of pH, accumulation potential and accumulation time. Under optimal conditions, the electrode offered linearity in the wide concentration range from 25 to 490 ng cm-3 and an estimated detection limit of 1.21 ng cm-3. Moreover, the electrode showed good stability, high selectivity and satisfactory anti-interference ability. Finally, the developed method was successfully applied for the determination of carbendazim traces in spiked tap and river water samples.

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