scholarly journals Chronic dieting and the belief that smoking controls body weight in a biracial, population-based adolescent sample

1997 ◽  
Vol 6 (2) ◽  
pp. 89-94 ◽  
Author(s):  
R. C. Klesges ◽  
V. E. Elliott ◽  
L. A. Robinson
2006 ◽  
Vol 28 (9) ◽  
pp. 1472-1481 ◽  
Author(s):  
Ezio Degli Esposti ◽  
Alessandra Sturani ◽  
Giorgia Valpiani ◽  
Mirko Di Martino ◽  
Francesco Ziccardi ◽  
...  

2016 ◽  
Vol 9 (4) ◽  
pp. 632-637 ◽  
Author(s):  
Jeroen S. de Munter ◽  
Per Tynelius ◽  
Gerd Ahlström ◽  
Finn Rasmussen

2022 ◽  
Vol 14 (1) ◽  
Author(s):  
Jiacheng He

Abstract Purpose Creatinine to body weight (Cre/BW) ratio is considered the independent risk factor for incident type 2 diabetes mellitus (T2DM), but research on this relationship is limited. The relationship between the Cre/BW ratio and T2DM among Chinse individuals is still ambiguous. This study aimed to evaluate the correlation between the Cre/BW ratio and the risk of T2DM in the Chinese population. Methods This is a retrospective cohort study from a prospectively collected database. We included a total of 200,658 adults free of T2DM at baseline. The risk of incident T2DM according to Cre/BW ratio was estimated using multivariable Cox proportional hazards models, and a two-piece wise linear regression model was developed to find out the threshold effect. Results With a median follow-up of 3.13 ± 0.94 years, a total of 4001 (1.99%) participants developed T2DM. Overall, there was an L-shaped relation of Cre/BW ratio with the risk of incident T2DM (P for non-linearity < 0.001). When the Cre/BW ratio (× 100) was less than 0.86, the risk of T2DM decreased significantly as the Cre/BW ratio increased [0.01 (0.00, 0.10), P < 0.001]. When the Cre/BW ratio (× 100) was between 0.86 and 1.36, the reduction in the risk of developing T2DM was not as significant as before [0.22 (0.12, 0.38), P < 0.001]. In contrast, when the Cre/BW ratio (× 100) was greater than 1.36, the reduction in T2DM incidence became significantly flatter than before [0.73 (0.29,1.8), P = 0.49]. Conclusion There was an L-shaped relation of Cre/BW ratio with incidence of T2DM in general Chinese adults. A negative curvilinear association between Cre/BW ratio and incident T2DM was present, with a saturation effect predicted at 0.86 and 1.36 of Cre/BW ratio (× 100).


2015 ◽  
Vol 76 (06) ◽  
pp. e745-e751 ◽  
Author(s):  
Raymond Noordam ◽  
Nikkie Aarts ◽  
Henning Tiemeier ◽  
Albert Hofman ◽  
Bruno H. Stricker ◽  
...  

2020 ◽  
Vol 91 (8) ◽  
pp. 867-875 ◽  
Author(s):  
Mark R Janse van Mantgem ◽  
Ruben P A van Eijk ◽  
Hannelore K van der Burgh ◽  
Harold H G Tan ◽  
Henk-Jan Westeneng ◽  
...  

ObjectiveTo determine the prevalence and prognostic value of weight loss (WL) prior to diagnosis in patients with amyotrophic lateral sclerosis (ALS).MethodsWe enrolled patients diagnosed with ALS between 2010 and 2018 in a population-based setting. At diagnosis, detailed information was obtained regarding the patient’s disease characteristics, anthropological changes, ALS-related genotypes and cognitive functioning. Complete survival data were obtained. Cox proportional hazard models were used to assess the association between WL and the risk of death during follow-up.ResultsThe data set comprised 2420 patients of whom 67.5% reported WL at diagnosis. WL occurred in 71.8% of the bulbar-onset and in 64.2% of the spinal-onset patients; the mean loss of body weight was 6.9% (95% CI 6.8 to 6.9) and 5.5% (95% CI 5.5 to 5.6), respectively (p<0.001). WL occurred in 35.1% of the patients without any symptom of dysphagia. WL is a strong independent predictor of survival, with a dose response relationship between the amount of WL and the risk of death: the risk of death during follow-up increased by 23% for every 10% increase in WL relative to body weight (HR 1.23, 95% CI 1.13 to 1.51, p<0.001).ConclusionsThis population-based study shows that two-thirds of the patients with ALS have WL at diagnosis, which also occurs independent of dysphagia, and is related to survival. Our results suggest that WL is a multifactorial process that may differ from patient to patient. Gaining further insight in its underlying factors could prove essential for future therapeutic measures.


2009 ◽  
Vol 12 (7) ◽  
pp. 1015-1018 ◽  
Author(s):  
Vicente Martínez-Vizcaíno ◽  
Mairena Sánchez López ◽  
Pablo Moya Martínez ◽  
Montserrat Solera Martinez ◽  
Blanca Notario Pacheco ◽  
...  

AbstractBackgroundIn developed countries, there is abundant information on the epidemic of childhood obesity, but only a few studies on trends in the dual burden of body weight (overweight and thinness).ObjectiveTo examine trends in overweight and thinness among 9–10-year-old Spanish children in the last decade.MethodsData were taken from cross-sectional studies on schoolchildren in Cuenca (Spain), conducted in 1992, 1996, 1998 and 2004 with similar methods. Weight and height were measured by trained personnel with standardized procedures. Overweight (including obesity) and thinness were defined according with the International Obesity Taskforce BMI cut-offs.ResultsThe overall prevalence of overweight increased from 24·4 % in 1992 to 30·9 % in 2004 (P = 0·07), rising from 21·2 % in 1992 to 32·0 % in 2004 (P = 0·03) among boys and from 27·7 % to 29·8 % (P = 0·67) among girls. The overall prevalence of thinness was 2·7 % in 1992 and 9·2 % in 2004 (P < 0·001); in the same period, thinness prevalence rose from 1·9 % to 9·0 % (P = 0·10) among boys and from 3·7 % to 9·5 % (P < 0·01) among girls.ConclusionsThe dual burden of body weight has increased among children in Cuenca in the last decade. Population-based policies addressing childhood obesity, which is the most frequent problem, should not increase the risk of thinness.


2020 ◽  
Vol 11 ◽  
Author(s):  
Eun Roh ◽  
Soon Young Hwang ◽  
Jung A. Kim ◽  
You-Bin Lee ◽  
So-hyeon Hong ◽  
...  

2019 ◽  
Vol 131 (3) ◽  
pp. 501-511 ◽  
Author(s):  
Joakim Nyberg ◽  
Husong Li ◽  
Pehr Wessmark ◽  
Viktor Winther ◽  
Donald S. Prough ◽  
...  

Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Population-based, pharmacokinetic modeling can be used to describe variability in fluid distribution and dilution between individuals and across populations. The authors hypothesized that dilution produced by crystalloid infusion after hemorrhage would be larger in anesthetized than in awake subjects and that population kinetic modeling would identify differences in covariates. Methods Twelve healthy volunteers, seven females and five males, mean age 28 ± 4.3 yr, underwent a randomized crossover study. Each subject participated in two separate sessions, separated by four weeks, in which they were assigned to an awake or an anesthetized arm. After a baseline period, hemorrhage (7 ml/kg during 20 min) was induced, immediately followed by a 25 ml/kg infusion during 20 min of 0.9% saline. Hemoglobin concentrations, sampled every 5 min for 60 min then every 10 min for an additional 120 min, were used for population kinetic modeling. Covariates, including body weight, sex, and study arm (awake or anesthetized), were tested in the model building. The change in dilution was studied by analyzing area under the curve and maximum plasma dilution. Results Anesthetized subjects had larger plasma dilution than awake subjects. The analysis showed that females increased area under the curve and maximum plasma dilution by 17% (with 95% CI, 1.08 to 1.38 and 1.07 to 1.39) compared with men, and study arm (anesthetized increased area under the curve by 99% [0.88 to 2.45] and maximum plasma dilution by 35% [0.71 to 1.63]) impacted the plasma dilution whereas a 10-kg increase of body weight resulted in a small change (less than1% [0.93 to 1.20]) in area under the curve and maximum plasma dilution. Mean arterial pressure was lower in subjects while anesthetized (P &lt; 0.001). Conclusions In awake and anesthetized subjects subjected to controlled hemorrhage, plasma dilution increased with anesthesia, female sex, and lower body weight. Neither study arm nor body weight impact on area under the curve or maximum plasma dilution were statistically significant and therefore no effect can be established.


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