scholarly journals P2-250 Omega 3 polyunsaturated fatty acids (PUFAs) and risk of early onset prostate cancer

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A290-A291
Author(s):  
A. A. Ur Rahman ◽  
A. Lophatananon ◽  
J. Lobaz ◽  
F. Robinson ◽  
S. S. Brown ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Early Onset ◽  
Omega 3

scholarly journals Meta-Analysis of Long-Chain Omega-3 Polyunsaturated Fatty Acids (LCω-3PUFA) and Prostate Cancer

2015 ◽  
Vol 67 (4) ◽  
pp. 543-554 ◽  
Author(s):  
Dominik D. Alexander ◽  
Julie K. Bassett ◽  
Douglas L. Weed ◽  
Erin Cernkovich Barrett ◽  
Heather Watson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Meta Analysis ◽  
Omega 3 ◽  
Long Chain

scholarly journals A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1647
Author(s):  
Karin Yurko-Mauro ◽  
Mary Van Elswyk ◽  
Lynn Teo
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Polyunsaturated Fatty Acids ◽  
Scoping Review ◽  
Genetic Variants ◽  
Prostate Cancer Risk ◽  
Lymphocytic Leukemia ◽  
Omega 3 ◽  
Long Chain

This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast cancer (n = 2), gastric cancer (n = 1), exocrine pancreatic cancer (n = 1), chronic lymphocytic leukemia (n = 1), prostate cancer (n = 7) and colorectal cancer (n = 6). An additional 13 studies that focused on fish intake or at-risk populations were summarized to increase readers’ understanding of the topic based on this review, DHA and EPA interact with certain genetic variants to decrease breast, colorectal and prostate cancer risk, although data was limited and identified polymorphisms were heterogeneous. The evidence to date demonstrates that omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) may decrease cancer risk by affecting genetic variants of inflammatory pathways, oxidative stress and tumor apoptosis. Collectively, data supports the notion that once a genetic variant is identified, the benefits of a targeted, personalized therapeutic regimen that includes DHA and/or EPA should be considered.

scholarly journals Mechanisms of Omega-3 Polyunsaturated Fatty Acids in Prostate Cancer Prevention

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Zhennan Gu ◽  
Janel Suburu ◽  
Haiqin Chen ◽  
Yong Q. Chen
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Cancer Prevention ◽  
Polyunsaturated Fatty Acid ◽  
Omega 3 ◽  
Prostate Cancer Prevention

This review focuses on several key areas where progress has been made recently to highlight the role of omega-3 polyunsaturated fatty acid in prostate cancer prevention.

A randomized, double-blind, placebo-controlled study of polyunsaturated fatty acids efficacy in adolescents with anorexia nervosa

2020 ◽  
Vol 36 (2) ◽  
pp. 95-106
Author(s):  
Agnieszka M. Piróg-Balcerzak ◽  
Anna K. Bażyńska ◽  
Katarzyna Biernacka ◽  
Joanna Brągoszewska ◽  
Lidia Popek ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Anorexia Nervosa ◽  
Polyunsaturated Fatty Acids ◽  
Small Sample Size ◽  
Small Sample ◽  
Female Adolescent ◽  
Eating Attitude ◽  
Controlled Study ◽  
Omega 3 ◽  
Eat 26

Objective. Omega–3 polyunsaturated fatty acids (PUFAs) were tested in adolescent depression and in several neurodevelopmental disorders with partial success. Anorexia nervosa (AN) is characterised by deficiencies in fatty food intake and frequent comorbidity, including depressive and cognitive symptoms. Thus supplementation with PUFAs may be beneficial in this group of patients. The aim of the study was to assess whether PUFAs as an add-on treatment is associated with better improvement of body mass index (BMI) and psychopathological symptoms than placebo in patients with AN. Method. 61 female adolescent inpatients with AN were randomly allocated to omega–3 PUFAs supplementation or placebo for 10 weeks. Patients also participated in the behavioural programme and eclectic psychotherapy (treatment as usual, TAU). At baseline and follow-up visits, patients’ BMI and psychopathology were assessed with Clinical Global Impression Scale (CGI), Patient Global Impression Scale (PGI), and Eating Attitude Test (EAT-26). Results. After 10 weeks, both groups showed improvement in all parameters. Improvement in CGI scores was observed greater in placebo vs. PUFA-s group (p = 0.015) while other differences were not statistically significant. Omega–3 PUFAs supplementation appears not to be effective as an add-on treatment in inpatient adolescent girls with anorexia nervosa. Conclusions. The results should be analysed with caution due to small sample size and heterogeneity in TAU. As the TAU turned out to be highly effective, additional therapeutic effect of PUFA might not be visible. Nevertheless, that does not explain the tendency for better improvement in the placebo group.

Omega-3 Polyunsaturated Fatty Acids and Cancer

2013 ◽  
Vol 13 (8) ◽  
pp. 1162-1177 ◽  
Author(s):  
Kaipeng Jing ◽  
Tong Wu ◽  
Kyu Lim
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Omega 3
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