Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis

PROTEOMICS ◽  
2016 ◽  
Vol 16 (17) ◽  
pp. 2419-2431 ◽  
Author(s):  
Heng Zhao ◽  
Beth R. Pflug ◽  
Xianyin Lai ◽  
Mu Wang
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Pyruvate Dehydrogenase ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Omega 3

scholarly journals Omega-3 Fatty Acids and Other FFA4 Agonists Inhibit Growth Factor Signaling in Human Prostate Cancer Cells

2014 ◽  
Vol 352 (2) ◽  
pp. 380-394 ◽  
Author(s):  
Ze Liu ◽  
Mandi M. Hopkins ◽  
Zhihong Zhang ◽  
Chrystal B. Quisenberry ◽  
Louise C. Fix ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Prostate ◽  
Growth Factor Signaling ◽  
Human Prostate Cancer ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Prostate Cancer Cells

scholarly journals P2-250 Omega 3 polyunsaturated fatty acids (PUFAs) and risk of early onset prostate cancer

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A290-A291
Author(s):  
A. A. Ur Rahman ◽  
A. Lophatananon ◽  
J. Lobaz ◽  
F. Robinson ◽  
S. S. Brown ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Early Onset ◽  
Omega 3

scholarly journals Meta-Analysis of Long-Chain Omega-3 Polyunsaturated Fatty Acids (LCω-3PUFA) and Prostate Cancer

2015 ◽  
Vol 67 (4) ◽  
pp. 543-554 ◽  
Author(s):  
Dominik D. Alexander ◽  
Julie K. Bassett ◽  
Douglas L. Weed ◽  
Erin Cernkovich Barrett ◽  
Heather Watson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Meta Analysis ◽  
Omega 3 ◽  
Long Chain

scholarly journals A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1647
Author(s):  
Karin Yurko-Mauro ◽  
Mary Van Elswyk ◽  
Lynn Teo
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Polyunsaturated Fatty Acids ◽  
Scoping Review ◽  
Genetic Variants ◽  
Prostate Cancer Risk ◽  
Lymphocytic Leukemia ◽  
Omega 3 ◽  
Long Chain

This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast cancer (n = 2), gastric cancer (n = 1), exocrine pancreatic cancer (n = 1), chronic lymphocytic leukemia (n = 1), prostate cancer (n = 7) and colorectal cancer (n = 6). An additional 13 studies that focused on fish intake or at-risk populations were summarized to increase readers’ understanding of the topic based on this review, DHA and EPA interact with certain genetic variants to decrease breast, colorectal and prostate cancer risk, although data was limited and identified polymorphisms were heterogeneous. The evidence to date demonstrates that omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) may decrease cancer risk by affecting genetic variants of inflammatory pathways, oxidative stress and tumor apoptosis. Collectively, data supports the notion that once a genetic variant is identified, the benefits of a targeted, personalized therapeutic regimen that includes DHA and/or EPA should be considered.

scholarly journals Mechanisms of Omega-3 Polyunsaturated Fatty Acids in Prostate Cancer Prevention

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Zhennan Gu ◽  
Janel Suburu ◽  
Haiqin Chen ◽  
Yong Q. Chen
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Cancer Prevention ◽  
Polyunsaturated Fatty Acid ◽  
Omega 3 ◽  
Prostate Cancer Prevention

This review focuses on several key areas where progress has been made recently to highlight the role of omega-3 polyunsaturated fatty acid in prostate cancer prevention.

scholarly journals The Combination of Omega-3 Stearidonic Acid and Docetaxel Enhances Cell Death over Docetaxel Alone in Human Prostate Cancer Cells

2018 ◽  
Vol 9 (23) ◽  
pp. 4536-4546 ◽  
Author(s):  
Mahmoud Mansour ◽  
Sabrina van Ginkel ◽  
John C. Dennis ◽  
Brandon Mason ◽  
Isra Elhussin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Stearidonic Acid ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Omega 3 ◽  
Prostate Cancer Cells
Sign in / Sign up

Export Citation Format

Share Document