scholarly journals Myocardial bridging in a survivor of sudden cardiac near-death: role of intracoronary doppler flow measurements and angiography during dobutamine stress in the clinical evaluation.

Heart ◽  
1997 ◽  
Vol 77 (3) ◽  
pp. 280-282 ◽  
Author(s):  
R. A. Tio ◽  
I. C. Van Gelder ◽  
P. W. Boonstra ◽  
H. J. Crijns
Keyword(s):  
Clinical Evaluation ◽  
Dobutamine Stress ◽  
Myocardial Bridging ◽  
Flow Measurements ◽  
Doppler Flow ◽  
Intracoronary Doppler

scholarly journals Does Coronary Microvascular Spasm Exist? Objective Evidence from Intracoronary Doppler Flow Measurements During Acetylcholine Testing

2020 ◽  
Vol 4 (3) ◽  
pp. 205-209
Author(s):  
Fabian Guenther ◽  
Andreas Seitz ◽  
Valeria Martínez Pereyra ◽  
Raffi Bekeredjian ◽  
Udo Sechtem ◽  
...  
Keyword(s):  
Coronary Flow ◽  
Coronary Spasm ◽  
Coronary Microvascular Dysfunction ◽  
Flow Measurements ◽  
Doppler Flow ◽  
Intracoronary Doppler ◽  
Intracoronary Administration ◽  
Objective Evidence ◽  
Microvascular Spasm ◽  
Provocation Testing

A 43-year-old woman with recurrent atypical angina underwent invasive coronary angiography including intracoronary Doppler blood flow assessment and coronary spasm provocation testing. While obstructive epicardial disease could be ruled-out angiographically, the patient experienced reproduction of her angina symptoms after intracoronary administration of acetylcholine (100 µg) during spasm provocation testing. Simultaneously, the ECG showed new-onset ST-segment depression in the absence of epicardial spasm. In addition, coronary flow velocity was significantly reduced after acetylcholine compared to the baseline condition. Following intracoronary administration of nitroglycerine (200 µg), the patient’s symptoms as well as the ECG changes and coronary flow reduction were reversed. Considering the ongoing challenges in appropriate evaluation of the pathophysiological mechanisms of coronary microvascular dysfunction, simultaneous intracoronary Doppler flow measurement during spasm testing ‐ as shown in this case ‐ may provide objective evidence for microvascular spasm in addition to the standardized diagnostic criteria, especially if they are ambiguous.

scholarly journals Functional characteristics of myocardial bridging: A combined angiographic and intracoronary Doppler flow study

1997 ◽  
Vol 18 (3) ◽  
pp. 434-442 ◽  
Author(s):  
E. R. Schwarz ◽  
H. G. Klues ◽  
J. vom Dahl ◽  
I. Klein ◽  
W. Krebs ◽  
...  
Keyword(s):  
Myocardial Bridging ◽  
Functional Characteristics ◽  
Doppler Flow ◽  
Intracoronary Doppler ◽  
Flow Study

The Role of Myocardial Perfusion Imaging in the Clinical Evaluation of Coronary Artery Disease in Women

2006 ◽  
Vol 3 (2) ◽  
pp. 68-72
Author(s):  
Jennifer Mieres ◽  
Leslee J Shaw ◽  
Robert C Hendel ◽  
D Douglas Miller ◽  
Robert Bonow ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Clinical Evaluation ◽  
Perfusion Imaging ◽  
Artery Disease

scholarly journals The Role of Electrode Size on the Incidence of Spreading Depression and on Cortical Cerebral Blood Flow as Measured by H2 Clearance

1992 ◽  
Vol 12 (2) ◽  
pp. 230-237 ◽  
Author(s):  
Marleen J. Verhaegen ◽  
Michael M. Todd ◽  
David S. Warner ◽  
Bruce James ◽  
Julie B. Weeks
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Gray Matter ◽  
Spreading Depression ◽  
Insertion Depth ◽  
Flow Measurements ◽  
Electrode Size ◽  
Cortical Gray Matter ◽  
The Right

Cerebral blood flow was measured by the H2 clearance method 30 and 60 min after the implantation of 300, 250, 125, or 50 μm diameter platinum–iridium electrodes 2 mm deep into the right parietal cortex of normothermic, normocarbic halothane-anesthetized rats. Another group of animals had 50 μm electrodes inserted 1 mm. In all animals, the presence or absence of a wave of spreading depression (SD) was noted at the time of implantation, with recordings made with glass micropipettes. H2 flow values were compared with those measured in gray matter from the same anatomical region (but from different rats), using [3H]nicotine. The incidence of SD ranged from 60% following insertion of 300 μm electrodes to 0% with 50 μm electrodes. H2 clearance flows also varied with electrode size, from 77 ± 21 ml 100 g−1 min−1 (mean ± standard deviation) with 300 μm electrodes to 110 ± 31 and 111 ± 16 ml 100 g−1 min−1 with 125 and 50 μm electrodes, respectively (insertion depth of 2 mm). A CBF value of 155 ± 60 ml 100 g−1 min−1 was obtained with 50 μm electrodes inserted only 1 mm. Cortical gray matter blood flow measured with [3H]nicotine was 154 ± 35 ml 100 g−1 min−1. When the role of SD in subsequent flow measurements was examined, there was a gradual increase in CBF between 30 and 60 min after electrode insertion in those animals with SD, while no such change was seen in rats without SD. These results indicate that the choice of electrode size and implantation depth influences the measurement of CBF by H2 clearance. CBF values equivalent to those obtained with isotopic techniques can be acutely obtained with small (50 μm diameter) electrodes inserted 1 mm into the cortex. While the occurrence of SD does influence CBF in the period immediately after implantation, a relationship between electrode size and measured flow is present that is independent of SD.

scholarly journals The Role of Self- and Informant-Reports on Symptoms and Impairments in the Clinical Evaluation of Adult ADHD

2021 ◽  
Vol 13 (8) ◽  
pp. 4564
Author(s):  
Nana Guo ◽  
Anselm B. M. Fuermaier ◽  
Janneke Koerts ◽  
Bernhard W. Mueller ◽  
Christian Mette ◽  
...  
Keyword(s):  
Clinical Evaluation ◽  
Test Performance ◽  
Adult Adhd ◽  
Comparison Group ◽  
Neuropsychological Test ◽  
Neuropsychological Testing ◽  
Adhd Group ◽  
Adhd Symptoms ◽  
Clinical Comparison

Little is known about which clinical features may aid the differentiation between attention deficit hyperactivity disorder (ADHD) and other clinical conditions. This study seeks to determine the role of self- and informant reports on symptoms and impairments in the clinical evaluation of adult ADHD and explore their association with objective neuropsychological test performance by examining data of 169 outpatients referred for a diagnostic evaluation of adult ADHD. Participants were assigned either to an ADHD group (ADHD, n = 73) or one of two clinical comparison groups, depending on whether they show indications (Clinical Comparison Group, CCG, n = 53) or no indications (Clinical Comparison Group—Not Diagnosed, CCG-ND, n = 43) of psychiatric disorders other than ADHD. All participants and their informants completed a set of questionnaires. Compared to the CCG-ND, the ADHD group obtained significantly higher scores on ADHD symptoms, impulsivity, cognitive deficits, and anxiety. Compared to the CCG, the ADHD group scored significantly higher on ADHD symptoms but lower on depression. Further regression analyses revealed that self- and informant reports failed to predict neuropsychological test performance. Self- and informant reported information may be distinct features and do not correspond to results of objective neuropsychological testing.

scholarly journals Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia

2012 ◽  
pp. 43 ◽  
Author(s):  
Marcos Restrepo ◽  
Diego J. Maselli ◽  
Juan F. Fernandez ◽  
Kelly Echevarria ◽  
Anoop Nambiar ◽  
...  
Keyword(s):  
Clinical Evaluation ◽  
Bacterial Pneumonia
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