scholarly journals Early onset group B streptococcal neonatal infection in Oxford 1985-96

1998 ◽  
Vol 79 (2) ◽  
pp. F148-F149 ◽  
Author(s):  
L. M Moses ◽  
P T Heath ◽  
A R Wilkinson ◽  
H E Jeffery ◽  
D Isaacs
Keyword(s):  
Early Onset ◽  
Neonatal Infection ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group

scholarly journals Effect of Resident Physician Education Regarding Selective Chemoprophylaxis for the Prevention of Early Onset Group B Streptococcal Sepsis: An Outcome Study

1994 ◽  
Vol 1 (5) ◽  
pp. 210-215
Author(s):  
Jeffrey S. Greenspoon ◽  
Doron J. D. Rosen ◽  
Anita P. Sumen
Keyword(s):  
Risk Factors ◽  
Education Program ◽  
Early Onset ◽  
Neonatal Infection ◽  
Physician Education ◽  
Streptococcal Sepsis ◽  
The Difference ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group

Objective:The aim of this study was to evaluate the effect of a voluntary protocol for selective intrapartum chemoprophylaxis on the incidence of early onset group B streptococcal sepsis (GBS EOS).Methods:Cases of GBS EOS were defined as a positive GBS culture from a normally sterile fluid obtained during the first 7 days of life. All cases of GBS EOS at an urban, university-affiliated community hospital were reviewed during 2 time periods. The 2-year period before instituting a resident education program to promote selective chemoprophylaxis (1988–89) was retrospectively reviewed; the 2-year period after the education program was introduced (1990–91) was prospectively recorded. The outcome measure was the incidence of GBS EOS.Results:The rate of GBS EOS was 7/14,335 deliveries (0.05%) before and 9/13,999 (0.064%) after the introduction of the education program (observed difference between proportions 0.016%, 95% confidence interval [CI] for the difference between the proportions –0.071% to 0.04%,P= not significant [NS]). The rate of GBS EOS in preterm infants was 5/1,331 (0.376%) before and 3/1,297 (0.23%) afterward (observed difference between proportions 0.14%, 95% CI –0.28% to 0.56%,P= NS). The incidence of GBS EOS did not decrease during the latter period due to failure of antepartum cultures to predict intrapartum GBS colonization (2 cases); non-compliance with voluntary recommendations to administer chemoprophylaxis (2 cases); failure of chemoprophylaxis or therapy for intraamniotic infection to prevent neonatal infection (3 cases); and occurrence of GBS EOS in infants without risk factors (2 cases).Conclusions:An education program for resident physicians regarding chemoprophylaxis for GBS EOS did not significantly reduce the absolute incidence of disease. Alternative strategies are needed that redress the causes of failure inherent in the current guidelines. Some cases of GBS EOS are not preventable because the parturient does not have risk factors that indicate chemoprophylaxis.

A Comparison of Early-Onset Group B Streptococcal Neonatal Infection and the Respiratory-Distress Syndrome of the Newborn

1976 ◽  
Vol 294 (2) ◽  
pp. 65-70 ◽  
Author(s):  
Ronald C. Ablow ◽  
Shirley G. Driscoll ◽  
Eric L. Effmann ◽  
Ian Gross ◽  
Christopher J. Jolles ◽  
...  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Early Onset ◽  
Distress Syndrome ◽  
Neonatal Infection ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group

Intrapartum chemoprophylaxis of early-onset group B streptococcal disease

1991 ◽  
Vol 40 (1) ◽  
pp. 57-62 ◽  
Author(s):  
R. Matorras ◽  
A. García-Perea ◽  
F. Omeñaca ◽  
M. Diez-Enciso ◽  
R. Madero ◽  
...  
Keyword(s):  
Early Onset ◽  
Streptococcal Disease ◽  
Group B Streptococcal Disease ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group

Decreasing mortality in neonates with early-onset group B streptococcal infection: Reality or artifact

1981 ◽  
Vol 98 (4) ◽  
pp. 625-627 ◽  
Author(s):  
Suma P. Pyati ◽  
Rosita S. Pildes ◽  
Rajam S. Ramamurthy ◽  
Norman Jacobs
Keyword(s):  
Early Onset ◽  
Streptococcal Infection ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group

scholarly journals Continued early onset group B streptococcal infections in the era of intrapartum prophylaxis

2008 ◽  
Vol 29 (1) ◽  
pp. 20-25 ◽  
Author(s):  
L S Pulver ◽  
M M Hopfenbeck ◽  
P C Young ◽  
G J Stoddard ◽  
K Korgenski ◽  
...  
Keyword(s):  
Early Onset ◽  
Streptococcal Infections ◽  
Group B ◽  
Onset Group ◽  
Early Onset Group
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