scholarly journals High resolution manometry and multichannel intraluminal impedance oesophageal manometry in clinical practice

2010 ◽  
Vol 1 (2) ◽  
pp. 112-117
Author(s):  
I. Mainie
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Multichannel Intraluminal Impedance ◽  
High Resolution Manometry ◽  
Oesophageal Manometry ◽  
Intraluminal Impedance

scholarly journals Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kazumasa Muta ◽  
Eikichi Ihara ◽  
Shohei Hamada ◽  
Hiroko Ikeda ◽  
Masafumi Wada ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Observational Study ◽  
Lower Esophageal Sphincter ◽  
Relaxation Function ◽  
Esophagogastric Junction ◽  
Prospective Observational Study ◽  
Outflow Obstruction ◽  
High Resolution Manometry ◽  
Esophageal Sphincter

AbstractThe preparatory accommodation response of lower esophageal sphincter (LES) before swallowing is one of the mechanisms involved in LES relaxation during wet swallows, however, the physiological and/or pathological roles of LES accommodation remain to be determined in humans. To address this problem, we conducted a prospective observational study of 38 patients with normal high-resolution manometry (HRM) and 23 patients with idiopathic esophagogastric junction outflow obstruction (EGJOO) to assess dry and wet swallows. The LES accommodation measurement was proposed for practical use in evaluating the LES accommodation response. Although swallow-induced LES relaxation was observed in both dry and wet swallows, LES accommodation (6.4, 3.1–11.1 mmHg) was only observed in wet swallows. The extent of LES accommodation was impaired in idiopathic EGJOO (0.6, − 0.6–6 mmHg), and the LES accommodation measurement of patients with idiopathic EGJOO (36.8, 29.5–44.3 mmHg) was significantly higher in comparison to those with normal HRM (23.8, 18–28.6 mmHg). Successful LES relaxation in wet swallowing can be achieved by LES accommodation in combination with swallow-induced LES relaxation. Impaired LES accommodation is characteristic of idiopathic EGJOO. In addition to the IRP value, the LES accommodation measurement may be useful for evaluating the LES relaxation function in clinical practice.

scholarly journals How Updates in Chicago Classification Impact Clinical Practice

2021 ◽  
pp. 263451612110398
Author(s):  
Rena Yadlapati ◽  
Peter J. Kahrilas
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Patient Outcomes ◽  
Clinical Application ◽  
High Resolution Manometry ◽  
Chicago Classification

Chicago Classification version 4.0 (CC v4.0), published in 2021, presents several modifications largely aimed at minimizing over-diagnosis of inconclusive patterns on high-resolution manometry (HRM). These include: (1) introduction of a standardized HRM protocol for consistency among centers, (2) emphasis on the need for supportive data in instances of inconclusive manometric patterns, (3) required presence of relevant symptoms in certain instances to reduce over-diagnosis and inappropriate interventions, and (4) classification as disorders of EGJ outflow or disorders of peristalsis. These updates aim to improve the clinical application of HRM and patient outcomes.

scholarly journals Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Feng Gao ◽  
Yan Gao ◽  
Xue Chen ◽  
Jie Qian ◽  
Jie Zhang
Keyword(s):  
Chinese Patients ◽  
Multichannel Intraluminal Impedance ◽  
Esophageal Function ◽  
Functional Heartburn ◽  
High Resolution Manometry ◽  
Ineffective Esophageal Motility ◽  
Function Tests ◽  
Intraluminal Impedance ◽  
Total Reflux ◽  
Associated Symptoms

Objective. To investigate the differences in the results of esophageal function tests for functional heartburn (FH) and reflux hypersensitivity (RH). Methods. Patients with FH and RH and healthy volunteers (HVs) from the Department of Gastroenterology, Beijing Anzhen Hospital and Beijing Chao-Yang hospital, who underwent high-resolution manometry and impedance (HRIM), and 24-hour multichannel intraluminal impedance and pH recording (MII/pH) between 2014 and 2016, were enrolled in this study. Results. 36 HV, 147 FH patients, and 91 RH patients were enrolled. The postreflux swallow-induced peristaltic wave index (PSPW index) and mean nocturnal baseline impedance (MNBI) values were significantly lower in RH than in FH and HV. The ineffective esophageal motility (IEM), fragmented peristalsis rates, total bolus exposure, proximal total reflux events, and distal total reflux events were significantly greater in RH than in FH and HV. Conclusions. Compared to HV and FH patients, RH patients exhibited greater IEM and fragmented peristalsis rates, a greater total bolus exposure, more proximal total and distal total reflux events, and reduced chemical clearance and mucosal integrity. By using the above described parameters, HRIM and MII/pH assays could be used to correctly classify RH and FH and hence allow physicians to provide adequate relief from associated symptoms.

scholarly journals Esophageal manometry high-resolution in clinical practice.

2018 ◽  
Vol 95 (12) ◽  
pp. 1127-1136 ◽  
Author(s):  
I. V. Maev ◽  
E. V. Barkalova ◽  
M. A. Hovsepyan ◽  
Yu. A. Kucheryavy ◽  
Dmitry N. Andreyev
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Motor Function ◽  
Esophageal Manometry ◽  
Promising Method ◽  
Thoracic Esophagus ◽  
Current Clinical Practice ◽  
High Resolution Manometry ◽  
Diagnostic Capabilities

At present, esophageal manometry high-resolution (high resolution manometry, HRM) is a highly informative and promising method for diagnosing patients with different disorders of the motor function of the thoracic esophagus and disorders of tone of the sphincter apparatus. This article presents a series of observations that demonstrate the diagnostic capabilities of the methodology in current clinical practice.

Utility of Esophageal High-Resolution Manometry in Clinical Practice: First, Do HRM

2018 ◽  
Vol 63 (12) ◽  
pp. 3178-3186 ◽  
Author(s):  
Ishita Dhawan ◽  
Brendon O’Connell ◽  
Amit Patel ◽  
Ron Schey ◽  
Henry P. Parkman ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
High Resolution Manometry
Sign in / Sign up

Export Citation Format

Share Document