Vitamin D has a greater impact on cancer mortality rates than on cancer incidence rates

BMJ ◽  
2014 ◽  
Vol 348 (apr29 13) ◽  
pp. g2862-g2862 ◽  
Author(s):  
W. B. Grant ◽  
C. F. Garland
2020 ◽  
Vol 19 (2) ◽  
pp. 31-38
Author(s):  
G. M. Volgareva

Cervical cancer (CC) incidence rate made up about 5 % in overall women cancer incidence in Russia in 2015. CC morbidity rose by 24.47 % during 2005–2015. Despite the fact that aggregated standardized cancer mortality rates for both men and women during 2005–2015 declined, women CC mortality increased by 8.3 %. CC is the leading cancer mortality cause in women aged 30–39 years. Moreover growth of oral and pharynx cancer incidence rates in both genders as well as penile cancer in men all indicate to an unfavorable trend. The present Review part contains data on HPV-associated cancers in Russia, vertical HPV transition as well as preventive HPV vaccines.


2021 ◽  
Vol 39 (3_suppl) ◽  
pp. 457-457
Author(s):  
Ravina Sidhu ◽  
Perneet Powar ◽  
Ritu Priya Calla ◽  
Dinesh Vyas

457 Gastrointestinal Cancer Mortality Rate Global Trends Over the Last Century Background: Global gastroenterology cancer mortality trends have drastically changed over past decades due to alterations in risk factors such as diet, populations, exposures, and medical advancements. This study investigates specifically how meat consumption, the biggest evolving risk factor for GI cancer mortality, has influenced various gastrointestinal incidence rates globally. Although the correlation between meat consumption and cancer risk has been investigated, a global temporal study investigating the national mortality rates of gastrointestinal cancers relating to meat production remains unexplored. We researched causes for the trends between meat production and GI cancer mortality in the USA, Canada, Japan, France, and Singapore. Methods: Cancer mortality data was collected from the WHO Cancer Mortality Database, specifically the IARC database. Meat consumption data was unavailable between the 1960s-2010, so meat production data was used and obtained from the FAOSTAT. Results: The pancreatic cancer mortality rate increased in each country except Canada. This spike is due to increased meat consumption, obesity, lack of screening modalities, poor prognosis, and late diagnosis of the disease. Canada’s 1% drop in mortality rate can be attributed to a decreased smoking rate amongst men (62% to 16% from 1965-2017) as well as a decline in meat consumption. The mortality rates of gastric and colorectal cancer (CRC) have decreased despite a meat production increase. Decreased H. pylori prevalence (Europe: 48.8% to 39.8%, North America: 42.4% to 26.6%, and Western Asia: 53.6% to 54.3%) , better food preservation, and improvement in environmental conditions have lowered gastric cancer incidence. The CRC mortality rate in the USA, Canada, Japan, and France decreased mostly due to colonoscopy screening measures, better treatment, and decreased red meat consumption. In Singapore, increased obesity and high caloric diets account for an increased CRC mortality rate despite decreased meat production. This rate is exacerbated by lower screening rates due to decreased CRC risk awareness. Conclusions: Gastric and CRC mortality rates decreased despite increased meat production, while pancreatic cancer incidence rates have increased. These trends are further investigated and necessary to understand to lower the mortality rates of GI cancers on a global scale.


Author(s):  
Audrius Dulskas ◽  
Povilas Kavaliauskas ◽  
Kestutis Zagminas ◽  
Ligita Jancoriene ◽  
Giedre Smailyte

Background: Recently, reports have suggested that rates of liver cancer have increased during the last decades in developed countries; increasing hepatocellular carcinoma and cholangiocarcinoma rates were reported. The aim of this study was to examine time trends in incidence and mortality rates of liver cancer for the period of 1998–2015 in Lithuania by sex, age, and histology. Methods: We examined the incidence of liver cancer from 1998 to 2015 using data from the Lithuanian Cancer Registry. Age-standardized incidence rates were calculated by sex, age, and histology. Trends were analyzed using the Joinpoint Regression Program to estimate the annual percent change. Results: A total of 3086 primary liver cancer cases were diagnosed, and 2923 patients died from liver cancer. The total number of liver cancer cases changed from 132 in 1998 to 239 in 2015. Liver cancer incidence rates changed during the study period from 5.02/100,000 in 1998 to 10.54/100,000 in 2015 in men and from 2.43/100,000 in 1998 to 6.25/100,000 in 2015 in women. Annual percentage changes (APCs) in the age-standardized rates over this period were 4.5% for incidence and 3.6% for mortality. Hepatocellular cancer incidence rates were stable from 1998 to 2005 (APC −5.9, p = 0.1) and later increased by 6.7% per year (p < 0.001). Intrahepatic ductal carcinoma incidence increased by 8.9% per year throughout the study period. The rise in incidence was observed in all age groups; however, in age groups < 50 and between 70 and 79 years, observed changes were not statistically significant. For mortality, the significant point of trend change was detected in 2001, where after stable mortality, rates started to increase by 2.4% per year. Conclusions: Primary liver cancer incidence and mortality increased in both sexes in Lithuania. The rise om incidence was observed in both sexes and main histology groups. The increasing incidence trend may be related to the prevalence of main risk factors (alcohol consumption, hepatitis B and C infections. and diabetes).


1979 ◽  
Vol 1 (5) ◽  
pp. 147-152
Author(s):  
Jordan W. Finkelstein

Cancer is the fourth leading cause of death in the adolescent age group, preceded only by accidents, homicide, and suicide. Table 1 lists by age, sex, and race cancer incidence rates (per million) for a three-year period (1969-1971) reported by the National Cancer Institute. Table 2 lists the most commonly involved sites. There are significant differences between the younger and the older age groups. With the advent of improved treatment, survival rates have increased. Table 3 lists the survival rates for the most common forms of cancer and includes all children under 15 years of age. Although survival rates are increasing, the majority of children with cancer still die. Table 4 lists cancer mortality rates for adolescents. The issues involved in diagnosis, treatment, survival, and death present problems for all of those who care for the adolescent with cancer—the patient himself or herself, family and friends, the physician, and other health care professionals. The objectives of this article are: to increase awareness of the types of problems commonly encountered in caring for adolescents with cancer and to describe some of the ways of dealing with these problems. The problems are by no means clear-cut, and the suggested methods of dealing with them must be individualized to meet the needs of all involved.


2009 ◽  
Vol 8 (3) ◽  
pp. 143-147
Author(s):  
A. Ye. Pobilat ◽  
G. A. Arutyunyan

Scin neoplasms are among the most common oncological diseases with the prevalence of basalioma. The paper рresents statistical analysis of the data of skin cancer morbidity and mortality rates in Krasnoyarsk Region summarized for the period since 1999 until 2007. In structure of the skin cancer morbidity defines a share basalioma and squamous cell carcinoma.


2020 ◽  
Vol 19 (6) ◽  
pp. 19-27
Author(s):  
L. M. Minkina ◽  
M. M. Tsvetkov ◽  
Ya. S. Tikhonova ◽  
M. A. Postoykina

Background. Cancer is a leading cause of death in children and adolescents worldwide. The cancer incidence rate in children and adolescents has been on the rise for decades. Climatic, geographic and social factors of the region play an important role for cancer incidence.Objective: to analyze the cancer incidence and mortality rates in children and adolescents of Prymorsky krai.Methods. Cancer incidence rates in Russia for 2008–2018 as well as cancer incidence among children treated at the regional pediatric hematology/oncology center (Vladivostok, Russia) for 2014–2019 were analyzed.Results. No statistically significant differences in the cancer incidence rates for the 2008–2018 period between children and adolescents of Primorsky krai and the russian federation in the whole and the far-eastern federal district were found. In in Primorsky krai, there was a variability in the incidence rate during the analyzed period, a negative average annual growth rate in the group of children under 14 years of age (-0.86 %). For the 2008–2018 period, the cancer mortality rate in children and adolescents of Primorsky krai significantly decreased (from 5.65 ‰ in 2008 to 2.6 ‰ in 2018), with the average annual increase rate in children aged 017 years of -9.17 %. In 2014–2019, the quality of cancer detection improved significantly, and the number of children and adolescents with stage iiiiv cancer reduced.Conclusion. Cancer prevention and early detection can potentially reduce the cancer incidence and mortality rates in children and adolescents in Primorsky krai. Population-based cancer registries are needed for quantifying the burden of cancer in children and adolescents and assessing prevention and control programs.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Mirosław Jarosz ◽  
Włodzimierz Sekuła ◽  
Ewa Rychlik

The aim of the study was to investigate the relationship between pancreatic cancer incidence and selected dietary factors, alcohol consumption, and tobacco smoking in Poland in 1960–2008. Data on pancreatic cancer morbidity were derived from the National Cancer Registry and on food consumption from the national food balance sheets. In 1960–1989 correlations were found between pancreatic cancer incidence rates and energy (0.60 for males and 0.57 for females), cholesterol (0.87 and 0.80), fibre (−0.84 and −0.89) and folate (−0.45 and −0.49) intake, the consumption of total fats (0.94 and 0.91), animal fats (0,90 and 0,82), sugar (0.88 and 0.87), cereals (−0.93 and −0.91), and alcohol (0.86 and 0.82). In 1990–2008 morbidity correlated with the consumption of red meat (0.67 and 0.48), poultry (−0.88 and −0.57), and fruit (−0.62 and −0.50). Correlation with tobacco smoking was observed in the whole studied period (0.55 and 0.44). Increased incidence of pancreatic cancer in 1960–1995 was probably related to adverse dietary patterns up to 1989, especially high consumption of fats, sugar, and alcohol. Further positive changes in the diet such as lowering red meat consumption and increasing fruit consumption could influence incidence reduction in recent years. Also changes in tobacco smoking could affect the morbidity.


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