scholarly journals Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies

BMJ ◽  
2011 ◽  
Vol 343 (nov10 1) ◽  
pp. d6617-d6617 ◽  
Author(s):  
D. Aune ◽  
D. S. M. Chan ◽  
R. Lau ◽  
R. Vieira ◽  
D. C. Greenwood ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Dose Response ◽  
Prospective Studies ◽  
Dietary Fibre ◽  
Meta Analysis ◽  
Whole Grains

Different dietary fibre sources and risks of colorectal cancer and adenoma: a dose–response meta-analysis of prospective studies

2019 ◽  
Vol 122 (6) ◽  
pp. 605-615 ◽  
Author(s):  
Hannah Oh ◽  
Hanseul Kim ◽  
Dong Hoon Lee ◽  
Ariel Lee ◽  
Edward L. Giovannucci ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dose Response ◽  
Prospective Studies ◽  
Dietary Fibre ◽  
Meta Analysis ◽  
Folate Intake ◽  
Relative Risks ◽  
Important Health ◽  
Vegetable Fibre ◽  
Colorectal Cancer Prevention

AbstractDietary fibre is believed to provide important health benefits including protection from colorectal cancer. However, the evidence on the relationships with different dietary fibre sources is mixed and little is known about which fibre source provides the greatest benefits. We conducted a dose–response meta-analysis of prospective cohorts to summarise the relationships of different fibre sources with colorectal cancer and adenoma risks. Analyses were restricted to publications that reported all fibre sources (cereals, vegetables, fruits, legumes) to increase comparability between results. PubMed and Embase were searched through August 2018 to identify relevant studies. The summary relative risks (RR) and 95 % CI were estimated using a random-effects model. This analysis included a total of ten prospective studies. The summary RR of colorectal cancer associated with each 10 g/d increase in fibre intake were 0·91 (95 % CI 0·82, 1·00; I2 = 0 %) for cereal fibre, 0·95 (95 % CI 0·87, 1·03, I2 = 0 %) for vegetable fibre, 0·91 (95 % CI 0·78, 1·06, I2 = 43 %) for fruit fibre and 0·84 (95 % CI 0·63, 1·13, I2 = 45 %) for legume fibre. For cereal fibre, the association with colorectal cancer risk remained statistically significant after adjustment for folate intake (RR 0·89, 95 % CI 0·80, 0·99, I2 = 2 %). For vegetable and fruit fibres, the dose–response curve suggested evidence of non-linearity. All fibre sources were inversely associated with incident adenoma (per 10 g/d increase: RR 0·81 (95 % CI 0·54, 1·21) cereals, 0·84 (95 % CI 0·71, 0·98) for vegetables, 0·78 (95 % CI 0·65, 0·93) for fruits) but not associated with recurrent adenoma. Our data suggest that, although all fibre sources may provide some benefits, the evidence for colorectal cancer prevention is strongest for fibre from cereals/grains.

scholarly journals Antibiotic Use and Risk of Colorectal Cancer: A Systematic Review and Dose-Response Meta-Analysis

2020 ◽  
Author(s):  
Johanna Simin ◽  
Romina Fornes ◽  
Qing Liu ◽  
Renate Slind Olsen ◽  
Steven Callens ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Dose Response ◽  
Meta Analysis ◽  
Antibiotic Use

scholarly journals Antibiotic use and risk of colorectal cancer: a systematic review and dose–response meta-analysis

2020 ◽  
Vol 123 (12) ◽  
pp. 1825-1832
Author(s):  
Johanna Simin ◽  
Romina Fornes ◽  
Qing Liu ◽  
Renate Slind Olsen ◽  
Steven Callens ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Dose Response ◽  
Meta Analysis ◽  
Antibiotic Use

scholarly journals Anthropometric factors and ovarian cancer risk: A systematic review and nonlinear dose-response meta-analysis of prospective studies

2014 ◽  
Vol 136 (8) ◽  
pp. 1888-1898 ◽  
Author(s):  
Dagfinn Aune ◽  
Deborah A. Navarro Rosenblatt ◽  
Doris Sau Man Chan ◽  
Leila Abar ◽  
Snieguole Vingeliene ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Cancer ◽  
Cancer Risk ◽  
Dose Response ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Ovarian Cancer Risk

scholarly journals Anthropometric factors and endometrial cancer risk: a systematic review and dose–response meta-analysis of prospective studies

2015 ◽  
Vol 26 (8) ◽  
pp. 1635-1648 ◽  
Author(s):  
D. Aune ◽  
D.A. Navarro Rosenblatt ◽  
D.S.M. Chan ◽  
S. Vingeliene ◽  
L. Abar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Dose Response ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Endometrial Cancer Risk

scholarly journals Dietary fibre intake and risk of stroke: A systematic review and meta-analysis of prospective studies

2012 ◽  
Vol 71 (OCE3) ◽  
Author(s):  
D. E. Threapleton ◽  
D. C. Greenwood ◽  
C. E. Evans ◽  
C. L. Cleghorn ◽  
C. Nykjaer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prospective Studies ◽  
Dietary Fibre ◽  
Meta Analysis ◽  
Fibre Intake ◽  
Dietary Fibre Intake
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