scholarly journals Age related changes in the non-collagenous components of the extracellular matrix of the human lamina cribrosa

2000 ◽  
Vol 84 (3) ◽  
pp. 311-317 ◽  
Author(s):  
J. Albon
Keyword(s):  
Extracellular Matrix ◽  
Lamina Cribrosa ◽  
Age Related ◽  
Age Related Changes

Age-Related Changes in Scleral Material Properties of the Monkey Eye

2008 ◽  
Author(s):  
Michaël J. A. Girard ◽  
Jun-Kyo F. Suh ◽  
Michael Bottlang ◽  
Claude F. Burgoyne ◽  
J. Crawford Downs
Keyword(s):  
Intraocular Pressure ◽  
Material Properties ◽  
Lamina Cribrosa ◽  
Collagen Fibers ◽  
Visual Signals ◽  
Type I ◽  
Retinal Ganglion ◽  
Age Related ◽  
The Brain ◽  
Age Related Changes

The sclera is the outer shell and principal load-bearing tissue of the eye, which consists primarily of avascular lamellae of collagen fibers. Ninety percent of the collagen fibers in the sclera are Type I, which provide the eye with necessary mechanical strength to sustain intraocular pressure (IOP). In the posterior sclera, there is a fenestrated canal, called the optic nerve head (ONH), through which the retinal ganglion cell axons pass transmitting visual signals from the retina to the brain. The opening of the ONH is structurally supported by a fenestrated connective tissue called the lamina cribrosa.

scholarly journals Physiology of Vitreous and Vitreomacular Interface and Age-Related Changes

2018 ◽  
pp. 213-219
Keyword(s):  
Extracellular Matrix ◽  
Posterior Vitreous Detachment ◽  
Natural Aging ◽  
Posterior Segment ◽  
Vitreomacular Adhesion ◽  
Vitreoretinal Interface ◽  
Age Related ◽  
Ocular Structure ◽  
Vitreomacular Interface ◽  
Age Related Changes

Vitreous is an important ocular structure in the normal physiology and pathologic conditions of the posterior segment. Vitreous is a gel-like composite structure and forms an extracellular matrix that occupies the biggest space in the eye. The healthy vitreous gel reduces oxygen tension and protects vitreous, retina, and lens from oxidative damage. Vitreous plays an important role in the refraction of the eye, preserving the transparency with regular interaction of the macromolecules contained therein. Vitreous suffer from continuous physical tension and this results in important changes. Particularly age-related degeneration in the structure of the vitreous gel leads to a decrease in vitreoretinal adhesion. As part of natural aging, the posterior vitreous detachment process may become pathologic when the vitreoretinal interface weakens simultaneously with vitreous liquefaction. In this process, vision-threatening diseases such as vitreomacular adhesion, vitreomacular traction, and macula hole may appear.

scholarly journals Age-related changes in the thickness of the human lamina cribrosa

2006 ◽  
Vol 90 (12) ◽  
pp. 1531-1534 ◽  
Author(s):  
A Kotecha ◽  
S Izadi ◽  
G Jeffery
Keyword(s):  
Lamina Cribrosa ◽  
Age Related ◽  
Age Related Changes

Age-related changes of sulfated proteoglycans in the human lamina cribrosa

1993 ◽  
Vol 12 (8) ◽  
pp. 685-692 ◽  
Author(s):  
Shoichi Sawaguchi ◽  
Beatrice Y.J.T. Yue ◽  
Takeo Fukuchi ◽  
Kazuo Iwata ◽  
Tadayoshi Kaiya
Keyword(s):  
Lamina Cribrosa ◽  
Age Related ◽  
Age Related Changes ◽  
Sulfated Proteoglycans

Age-Related Changes in the Extracellular Matrix of the Human Optic Nerve Head

1989 ◽  
Vol 107 (5) ◽  
pp. 476-484 ◽  
Author(s):  
M. Rosario Hernandez ◽  
Xing Xing Luo ◽  
Wieslawa Andrzejewska ◽  
Arthur H. Neufeld
Keyword(s):  
Extracellular Matrix ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Age Related ◽  
Human Optic Nerve ◽  
Age Related Changes

Age-related changes of DRG neuronal attachment to extracellular matrix proteins in vitro

Neuroreport ◽  
1993 ◽  
Vol 4 (6) ◽  
pp. 663-666 ◽  
Author(s):  
Kazunori Sango ◽  
Hidenori Horie ◽  
Shuji Inoue ◽  
Yutaro Takamura ◽  
Toshifumi Takenaka
Keyword(s):  
Extracellular Matrix ◽  
Extracellular Matrix Proteins ◽  
Matrix Proteins ◽  
Age Related ◽  
Age Related Changes
Sign in / Sign up

Export Citation Format

Share Document