scholarly journals Ocular toxocariasis in a patient with repeatedly negative ELISA titre to Toxocara canis.

1993 ◽  
Vol 77 (4) ◽  
pp. 253-254 ◽  
Author(s):  
J A Sharkey ◽  
P S McKay
Keyword(s):  
Toxocara Canis ◽  
Ocular Toxocariasis ◽  
Elisa Titre

scholarly journals Adult Ocular Toxocariasis Mimicking Ciliary Body Malignancy

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ahmad M. Mansour ◽  
Bachir Abiad ◽  
Fouad I. Boulos ◽  
Ramzi Alameddine ◽  
Fadi C. Maalouf ◽  
...  
Keyword(s):  
Case Report ◽  
Local Excision ◽  
Rapid Growth ◽  
Ciliary Body ◽  
Inflammatory Cells ◽  
Toxocara Canis ◽  
Unusual Presentation ◽  
Medial Rectus ◽  
Ocular Toxocariasis ◽  
History Of

Purpose. To discuss an unusual presentation of ocular toxocariasis.Methods. Case report.Results. A 40-year-old woman presented with decreased vision in the left eye with a long history of recurrent red eye from uveitis. Eosinophilia and positive ELISA titers forToxocara canisfavored the diagnosis of ocular toxocariasis. Over 3 months, an anterior scleral mass had a rapid growth raising the possibility of medulloepithelioma, which rarely can mimic uveitic syndromes. Surgical plan changed from local excision to enucleation. Histopathology demonstrated a large homogeneous mass of chronic inflammatory cells with inflammation of the overlying thinned out sclera, medial rectus insertion, and limbal cornea. The triad of peripheral granuloma, eosinophilia, and positive blood serology established the diagnosis of ocular toxocariasis.Conclusions. Ocular toxocariasis can mimic ocular malignancy such as medulloepithelioma in adults and rarely presents as an anterior scleral mass.

Uveitis associated with Toxocara; Clinic, Diagnosis, and Treatment

2019 ◽  
pp. 244-246
Keyword(s):  
Parasitic Infection ◽  
Vitreoretinal Surgery ◽  
Toxocara Canis ◽  
Clinical Findings ◽  
Posterior Pole ◽  
Larva Migrans ◽  
Toxocara Cati ◽  
Ocular Toxocariasis ◽  
Fluid Analysis ◽  
Ocular Larva Migrans

Ocular toxocariasis or ocular larva migrans is a parasitic infection via the ingestion of dog nematode Toxocara canis and cat nematode Toxocara cati larvae. It usually affects only one eye of the child under the age of sixteen. The most common clinical findings in ocular toxocariasis are peripheral granuloma, posterior pole chorioretinal eosinophilic granulomas, and endophthalmitis or pars planitis. It is diagnosed with clinical findings in developing countries, ELISA antibody tests, and, if necessary, intraocular fluid analysis can be made. Ocular toxocariasis must be distinguished from retinoblastoma and other congenital and inflammatory eye conditions of childhood. In treatment, besides anthelmintic agents, steroid use and vitreoretinal surgery may be needed.

Ocular Toxocariasis Presenting as Endophthalmitis in a Young Adult Intravenous Drug User

2020 ◽  
pp. 247412642094658
Author(s):  
Pali P. Singh ◽  
Cason B. Robbins ◽  
Henry L. Feng ◽  
Durga S. Borkar ◽  
Sharon Fekrat
Keyword(s):  
Drug User ◽  
Intravenous Drug User ◽  
Toxocara Canis ◽  
Intravenous Drug ◽  
Intravenous Drug Use ◽  
Ocular Toxocariasis ◽  
Fundus Imaging ◽  
Common Causes ◽  
History Of ◽  
Optical Coherence Tomography Imaging

Purpose: This report describes the diagnosis of ocular toxocariasis presenting as endophthalmitis in an adult intravenous drug user. Methods: A case is reported. Results: Fundus imaging showed numerous white opacities obscuring the macula. Toxocara canis serology was reactive with an enzyme immunoassay titer of 1:2 (positive ≥ 1:32). Findings from bacterial and fungal cultures were negative, and vitrectomy cytology revealed no organisms. Postoperatively, serial optical coherence tomography imaging demonstrated a slight decrease in size of an intraretinal hyperreflective lesion in the macula. Conclusions: Owing to a variety of presentations, ocular toxocariasis can be challenging to diagnose. In a patient with a history of intravenous drug use where fungal and bacterial organisms are more common causes of endophthalmitis, it is important to have a wide differential of causative organisms, particularly in the context of negative culture results and a worsening clinical examination.

Evidence for the involvement of the optic nerve as a migration route for larvae in ocular toxocariasis of Mongolian gerbils

2003 ◽  
Vol 77 (4) ◽  
pp. 311-315 ◽  
Author(s):  
E. Hayashi ◽  
N. Akao ◽  
K. Fujita
Keyword(s):  
Optic Nerve ◽  
Late Phase ◽  
Toxocara Canis ◽  
Meriones Unguiculatus ◽  
Migration Route ◽  
Mongolian Gerbils ◽  
Ocular Toxocariasis ◽  
Optic Chiasma ◽  
Two Phases ◽  
The Brain

AbstractAlthough Toxocara canis, an important pathogen of ocular disease, tends to migrate to the eye, the precise migratory route has yet to be determined experimentally. Mongolian gerbils, Meriones unguiculatus, known as a useful animal model for human toxocariasis, were used to investigate the migration route toward the eyes. Infective larvae of T. canis were directly inoculated into the intracranial region. Haemorrhagic lesions or larvae were observed in 56.3% of cases. Histopathologically, a larva was observed in the optic nerve of gerbils 6 days after inoculation, and two larvae were found in the optic chiasma in the gerbils having a haemorrhage in the retina 9 days after inoculation. These results indicate that T. canis migrates from the brain to the eye through the optic nerve. Considering these data and previous studies showing that the ocular changes appear as early as 3 days of infection in the oral-administrated gerbils, there are two phases in the migration to the retina: a haematogenous early phase and an optic nerve route late phase.

scholarly journals Ocular toxocariasis caused by toxocara canis in an adult woman. Case report

Case reports ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 4-9 ◽  
Author(s):  
German Santiago Barahona Botache ◽  
Mario Javier Olivera
Keyword(s):  
Case Report ◽  
Toxoplasma Gondii ◽  
Taenia Solium ◽  
Toxocara Canis ◽  
Adult Woman ◽  
Toxocara Cati ◽  
Ocular Toxocariasis ◽  
Pars Planitis

Introducción. La toxocariasis es una zoonosis producida por las larvas de los nematodos Toxocara canis y Toxocara cati, parásitos intestinales de los cánidos y los félidos, respectivamente.Presentación del caso. Paciente femenino de 22 años de edad, procedente de Caquetá, Colombia, con un cuadro de 3 meses de evolución con pérdida de visión en ojo izquierdo, acompañada de dolor ocular, diplopía, fotofobia y ojo rojo bilateral, quien presenta desprendimiento de retina en ojo izquierdo diagnosticado por ecografía. La mujer asiste a oftalmología, donde se hace diagnóstico diferencial con retinoblastoma y pars planitis. Se inicia manejo sintomático con corticoides orales y tópicos, con mejoría de la sintomatología, pero persistencia de pérdida de la agudeza visual.Discusión. Al revisar historial de antecedentes socioeconómicos, la paciente convive con perros y gatos, por lo que se piensa en toxocariasis ocular. En el cuadro hemático se observa ligera leucocitosis y linfocitosis, sin eosinofilia. La determinación de anticuerpos anti-Toxoplasma gondii y anti-cisticerco de Taenia solium resultaron negativas, al igual que el VDRL. El test de ELISA para T. canis fue positivo, con unos títulos IgG de 1:64 (positivo ≥1:32, especificidad >90%). Se inicia manejo con corticoide oftálmico, sistémico, albendazol y vitrectomía. Con la intervención quirúrgica se libera banda vítrea, logrando la desaparición de la diplopía, pero persiste granuloma periférico residual, el cual será intervenido por oftalmología.Conclusiones. Dada la posibilidad de ser confundida con un retinoblastoma —una neoplasia maligna que puede requerir la enucleación del ojo—, el conocimiento de esta forma de presentación de la toxocariasis es de suma importancia para los clínicos. 

Ocular Toxocariasis Presenting as Leukocoria in a Patient with Low ELISA Titer to Toxocara canis

Ophthalmology ◽  
1981 ◽  
Vol 88 (12) ◽  
pp. 1302-1306 ◽  
Author(s):  
Steven S. Searl ◽  
Kambiz Moazed ◽  
Daniel M. Albert ◽  
Leonard C. Marcus
Keyword(s):  
Toxocara Canis ◽  
Ocular Toxocariasis ◽  
Elisa Titer

scholarly journals Frequency of Toxocara Antibodies in Patients Clinically Suspected to Ocular Toxocariasis, Northeast of Iran

2021 ◽  
Author(s):  
Abdolmajid Fata ◽  
Seyedeh Maryam Hosseini ◽  
Se Joon Woo ◽  
Se Joon Woo ◽  
Mohammad Zibaei ◽  
...  
Keyword(s):  
Vision Loss ◽  
Toxocara Canis ◽  
Elisa Test ◽  
Posterior Uveitis ◽  
Serum Samples ◽  
Igg Antibody ◽  
Ocular Toxocariasis ◽  
Clinical Presentations ◽  
Severe Vision Loss ◽  
Important Disease

Background: Human toxocariasis is a neglected parasitic disease in most countries including Iran. Among different clinical forms of toxocariasis, ocular toxocariasis (OT) is an important disease resulting in severe vision loss. However, the prevalence and incidence of OT are currently unclear in Iran. This study aimed to determine the prevalence of ocular toxocariasis among patients with uveitis in the Northeast of Iran. Methods: From 2015 to 2017, 510 patients with uveitis referred to Khatam-al-Anbia, a tertiary eye hospital at Mashhad, Iran were examined for OT. Serum samples of the suspected patients were obtained and evaluated for IgG against Toxocara canis using ELISA test. Anti-Toxocara IgG positive serums were further investigated using confirmatory Western blotting (WB) analysis. Results: Twenty patients had pathologic changes and clinical presentations in the anterior and posterior segments of their eyes and they were clinically diagnosed ocular toxocariasis. Among the 20 patients, 2 (10%) patients showed IgG antibody against Toxocara canis on ELISA as well as on WB test. The calculated prevalence of ocular toxocariasis was about 0.4%. Conclusion: Ocular toxocariasis can be diagnosed both clinically and serologically in Mashhad, northeastern Iran. Although OT is a rare pathologic eye disease, it should be considered as one of the important cause of infectious posterior uveitis.

scholarly journals Experimental Ocular Toxocariasis in Mice Infected with Long-term-maintained Embryonated Eggs of Toxocara canis

2004 ◽  
Vol 20 (7) ◽  
pp. 317-322 ◽  
Author(s):  
Chia-Kwung Fan ◽  
Yun-Ho Lin ◽  
Chien-Ching Hung ◽  
Kua-Eyre Su
Keyword(s):  
Toxocara Canis ◽  
Ocular Toxocariasis

scholarly journals Ocular toxocariasis: atypical clinical course

2019 ◽  
Vol 12 (4) ◽  
pp. e228717 ◽  
Author(s):  
Cristina Fonseca ◽  
Andreia Mendes Silva ◽  
Sandra Freire ◽  
Rui Proença
Keyword(s):  
Vision Loss ◽  
Clinical Course ◽  
Toxocara Canis ◽  
Ocular Toxocariasis ◽  
Presumptive Diagnosis ◽  
Macular Lesion ◽  
Oral Steroids ◽  
One Year ◽  
Field Defect

A 17-year-old man presented to the emergency department with complaints of retro-orbital pain of the left eye and an altitudinal visual field defect for 2 weeks. Fundus examination revealed ipsilateral hyperaemic optic disc oedema, and the patient was admitted with the presumptive diagnosis of left optic neuritis. Subsequently, during follow-up, the patient developed a retinal granulomatous lesion in the superior temporal arcade with vitritis and fibrotic strands extending to the mid-periphery. Serum antibodies detection by ELISA and aqueous humour immunoblot were positive for Toxocara canis. Medical therapy with albendazole and oral steroids was instituted with satisfactory results. One year later, a new macular lesion developed with consequent vision loss.

scholarly journals Diagnostic Aspects and Retinal Imaging in Ocular Toxocariasis: A Case Report from Italy

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Onelia Verallo ◽  
Serena Fragiotta ◽  
Francesca Verboschi ◽  
Enzo Maria Vingolo
Keyword(s):  
Visual Impairment ◽  
Morphological Changes ◽  
Toxocara Canis ◽  
Clinical Findings ◽  
Posterior Pole ◽  
Enzyme Linked Immunosorbent Assay ◽  
Exudative Retinal Detachment ◽  
Ocular Toxocariasis ◽  
Ocular Manifestations ◽  
Fundoscopic Examination

Toxocara canisis a nematode parasite, commonly found in dogs. This roundworm parasite can invade the eye, causing visual impairment.Toxocarashould be considered as a possible causative agent of posterior and diffuse uveitis, and it could be considered in the differential diagnosis of retinoblastoma. Ocular manifestations vary from severe endophthalmitis to silent incidental findings on a routine examination. We report a case of ocular toxocariasis in a 24-year-old Asiatic female that presented to us complaining of visual impairment. Fundoscopic examination revealed a posterior pole granuloma and exudative retinal detachment along with exudates. Presentation, clinical findings, morphological changes, and treatment are discussed. The enzyme-linked immunosorbent assay serology forToxocara caniswas performed, demonstrating the positivity for IgG and IgE. Treatment with the antihelminthic albendazole was initiated. Fluorescein angiography (FA; HRA 2, Heidelberg engineering) and optical coherence tomography (OCT; Spectralis, Heidelberg tomography) were performed, and results have been reported.

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