scholarly journals Projection OCT fundus imaging for visualising outer retinal pathology in non-exudative age-related macular degeneration

2008 ◽  
Vol 93 (5) ◽  
pp. 603-609 ◽  
Author(s):  
I Gorczynska ◽  
V J Srinivasan ◽  
L N Vuong ◽  
R W S Chen ◽  
J J Liu ◽  
...  
2022 ◽  
Vol 7 (4) ◽  
pp. 655-658
Author(s):  
Deepika Joshi ◽  
Sourav Shristi

To determine whether patients with Age related macular degeneration (ARMD) benefit from cataract surgery in terms of best corrected visual acuity (BCVA) and to assess impact of surgery on progression of ARMD.: A prospective study was carried out of patients with and without ARMD undergoing cataract surgery at our department. Patients were divided into two groups- Group A (cases) with ARMD and Group B (controls) without ARMD and other retinal pathology. BCVA of cases was recorded on day 1, day 14, 1 month and 1/month and compared to that of controls.: BCVA significantly improved but markedly less than that experienced by control eyes. No increased incidence in progression to wet form of ARMD. Cataract surgery is safe in ARMD patients with no evidence of increased complications or rates of disease advancement.


2022 ◽  
Vol 7 (1) ◽  
pp. e000912
Author(s):  
Caroline Brandl ◽  
Felix Günther ◽  
Martina E Zimmermann ◽  
Kathrin I Hartmann ◽  
Gregor Eberlein ◽  
...  

ObjectiveTo estimate age-related macular degeneration (AMD) incidence/progression across a wide age range.Methods and analysisAMD at baseline and follow-up (colour fundus imaging, Three Continent AMD Consortium Severity Scale, 3CACSS, clinical classification, CC) was assessed for 1513 individuals aged 35–95 years at baseline from three jointly designed population-based cohorts in Germany: Kooperative Gesundheitsforschung in der Region Augsburg (KORA-Fit, KORA-FF4) and Altersbezogene Untersuchungen zur Gesundheit der Universität Regensburg (AugUR) with 18-year, 14-year or 3-year follow-up, respectively. Baseline assessment included lifestyle, metabolic and genetic markers. We derived cumulative estimates, rates and risk factor association for: (1) incident early AMD, (2) incident late AMD among no AMD at baseline (definition 1), (3) incident late AMD among no/early AMD at baseline (definition 2), (4) progression from early to late AMD.ResultsIncidence/progression increased by age, except progression in 70+-year old. We observed 35–55-year-old with 3CACSS-based early AMD who progressed to late AMD. Predominant risk factor for incident late AMD definition 2 was early AMD followed by genetics and smoking. When separating incident late AMD definition 1 from progression (instead of combined as incident late AMD definition 2), estimates help judge an individual’s risk based on age and (3CACSS) early AMD status: for example, for a 65-year old, 3-year late AMD risk with no or early AMD is 0.5% or 7%, 3-year early AMD risk is 3%; for an 85-year old, these numbers are 0.5%, 21%, 12%, respectively. For CC-based ‘early/intermediate’ AMD, incidence was higher, but progression was lower.ConclusionWe provide a practical guide for AMD risk for ophthalmology practice and healthcare management and document a late AMD risk for individuals aged <55 years.


Yellowish pigmentation of the macula results from macular pigments called lutein, zeaxanthin, and mesozeaxanthin. Anatomical, biochemical (antioxidative) and optical (short-wavelength blue light absorption) properties of the macular pigments have increased the interest in vision and macular health. Macular pigments have been shown to have a protective role for age-related macular degeneration which is one of the leading causes of blindness all over the world. Macular pigments play an important role in the evaluation of the fundus imaging and diagnostic systems such as autofluorescence and angiography.


Retina ◽  
2018 ◽  
Vol 38 (10) ◽  
pp. 1930-1936 ◽  
Author(s):  
Jianqin Lei ◽  
Mayss Al-Sheikh ◽  
Yue Shi ◽  
Akihito Uji ◽  
Wenying Fan ◽  
...  

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