The change of oxidative stress products in diabetes mellitus and diabetic retinopathy

2008 ◽  
Vol 92 (4) ◽  
pp. 548-551 ◽  
Author(s):  
H.-Z. Pan ◽  
H. Zhang ◽  
D. Chang ◽  
H. Li ◽  
H. Sui
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Diabetic Retinopathy

scholarly journals Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology

2019 ◽  
Vol 2019 ◽  
pp. 1-21 ◽  
Author(s):  
Olvera-Montaño Cecilia ◽  
Castellanos-González José Alberto ◽  
Navarro-Partida José ◽  
Cardona-Muñoz Ernesto Germán ◽  
López-Contreras Ana Karen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Vision Impairment ◽  
Complications Of Diabetes ◽  
Cellular Degeneration ◽  
Neural Damage ◽  
Main Target ◽  
Focus Point

Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.

scholarly journals Sauchinone inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells

RSC Advances ◽  
2019 ◽  
Vol 9 (30) ◽  
pp. 17065-17071
Author(s):  
Yang Shi ◽  
Yongzhou Zhang ◽  
Yan Li ◽  
Chenjun Tong
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Retinal Pigment Epithelial ◽  
Retinal Pigment ◽  
Retinal Pigment Epithelial Cells ◽  
Common Complication ◽  
Pigment Epithelial ◽  
Working Age ◽  
Pigment Epithelial Cells

Diabetic retinopathy (DR) is a common complication of diabetes mellitus and results in acquired blindness among working-age adults.

scholarly journals Study on Glycemic Statusand Oxidative Stress Level in Patients of Type 2 Diabetes Mellitus With and Without Retinopathy: A Teaching Hospital Based Study

2020 ◽  
Vol 9 (1) ◽  
pp. OT01-OT04
Author(s):  
Rachana Gahlawat ◽  
Dinesh Narain Saksena
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Vitamin C ◽  
Antioxidant Status ◽  
Newly Diagnosed ◽  
Outpatient Services

Background: Diabetes is a chronic disease and sustained hyperglycemia attacks both micro vessels and macro vessels throughout the body. It is the leading cause of retinopathy, nephropathy, end-stage renal disease, non traumatic lower extremity amputations.Subjects and Methods:Twenty five (25) Patients with newly diagnosed type 2 diabetes mellitus without any signs of retinopathy were identified from outpatient services of department of Medicine and Twenty five (25) Patients with newly diagnosed type 2 diabetes mellitus with retinopathy were identified from outpatient services of department of Ophthalmology along with 25 healthy subjects were taken as controls. Diabetic retinopathy was diagnosed after doing detailed dilated fundoscopic examination as per the standard criteria.Results:The levels of FBS, HbA1c, total cholesterol, triglycerides and MDA were significantly higher in the diabetics without retinopathy, while the HDL and Vitamin C levels were lower as compared to those of the control group. The levels of FBS HbA1c, cholesterol, triglycerides and MDA were significantly higher in the diabetics with retinopathy, while the HDL and Vitamin C levels were lower as compared to those in the diabetes without retinopathy.Conclusion: The increased oxidative stress and a decreased antioxidant status can predict the micro-vascular complications in diabetes mellitus. The raised MDA levels indicate the oxidative stress and the decreased Vitamin C levels indicate the reduced antioxidant status in diabetic retinopathy.

Angiopoietin 1 in patients with type 2 diabetes mellitus and diabetic retinopathy

2015 ◽  
Author(s):  
Sattar El-Deeb Abd El ◽  
Mohamed Halawa ◽  
Ahmed Saad ◽  
Inas Sabry ◽  
Maram Mahdy ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Angiopoietin 1

Paper of oxidative stress and placenta on the development of gestational diabetes mellitus

2014 ◽  
Author(s):  
Cristina Lopez-Tinoco ◽  
Francisco Vilchez ◽  
Francisco Visiedo ◽  
Isabel Mateo ◽  
Carmen Segundo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus

Relationship between diabetic retinopathy and cerebral perfusion in type 2 diabetes mellitus

2018 ◽  
Vol 71 (1) ◽  
pp. 49-53
Author(s):  
N. Zherdiova ◽  
◽  
N. Medvedovska ◽  
B Mankovsky ◽  
◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Cerebral Perfusion
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