scholarly journals Association between synovial fluid levels of inorganic pyrophosphate and short term radiographic outcome of knee osteoarthritis.

1996 ◽  
Vol 55 (7) ◽  
pp. 432-436 ◽  
Author(s):  
M Doherty ◽  
C Belcher ◽  
M Regan ◽  
A Jones ◽  
J Ledingham
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Radiographic Outcome ◽  
Short Term ◽  
Inorganic Pyrophosphate ◽  
Fluid Levels

scholarly journals Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis

2010 ◽  
Vol 12 (6) ◽  
pp. R230 ◽  
Author(s):  
Staffan Larsson ◽  
Martin Englund ◽  
André Struglics ◽  
L Stefan Lohmander
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Radiographic Progression ◽  
Fluid Levels

scholarly journals Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis

2013 ◽  
Vol 21 (11) ◽  
pp. 1774-1780 ◽  
Author(s):  
F. Bellucci ◽  
S. Meini ◽  
P. Cucchi ◽  
C. Catalani ◽  
A. Nizzardo ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Biochemical Markers ◽  
Cartilage Degradation ◽  
Fluid Levels

scholarly journals Short-term sampling stability of synovial fluid measurements in knee osteoarthritis

2013 ◽  
Vol 21 ◽  
pp. S78-S79
Author(s):  
C. Jayadev ◽  
R. Rout ◽  
S. Snelling ◽  
P. Hulley ◽  
A. Price
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Short Term

scholarly journals Synovial Complement Factors in Patients with Periprosthetic Joint Infection after Undergoing Revision Arthroplasty of the Hip or Knee Joint

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 434
Author(s):  
Frank Sebastian Fröschen ◽  
Sophia Schell ◽  
Matthias Dominik Wimmer ◽  
Gunnar Thorben Rembert Hischebeth ◽  
Hendrik Kohlhof ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Multiple Regression ◽  
Complement System ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Expression Patterns ◽  
Factor H ◽  
Low Grade ◽  
Complement Factors ◽  
Fluid Levels

The role and diagnostic value of the synovial complement system in patients with low-grade periprosthetic joint infection (PJI) are unclear. We sought to evaluate, for the first time, the usefulness of synovial complement factors in these patients by measuring the individual synovial fluid levels of complement factors (C1q, C3b/iC3b, C4b, C5, C5a, C9, factor B, factor D, factor H, factor I, properdin, and mannose-binding lectin [MBL]). The patients (n = 74) were classified into septic (n = 28) and aseptic (n = 46). Receiver-operator characteristic curves and a multiple regression model to determine the feasibility of a combination of the tested cytokines to determine the infection status were calculated. The synovial fluid levels of C1q, C3b/C3i, C4b, C5, C5a, MBL, and properdin were significantly elevated in the PJI group. The best sensitivity and specificity was found for C1q. The multiple regression models revealed that the combination of C1q, C3b/C3i, C4b, C5, C5a, and MBL was associated with the best sensitivity (83.3%) and specificity (79.2%) for a cutoff value of 0.62 (likelihood ratio: 4.0; area under the curve: 0.853). Nevertheless, only a combined model showed acceptable results. The expression patterns of the complement factors suggested that PJI activates all three pathways of the complement system.

Sign in / Sign up

Export Citation Format

Share Document