scholarly journals Heparin modulates intracellular cyclic AMP in human trabecular bone cells and adherent rheumatoid synovial cells.

1984 ◽  
Vol 43 (4) ◽  
pp. 628-634 ◽  
Author(s):  
A J Crisp ◽  
M S Roelke ◽  
S R Goldring ◽  
S M Krane
Keyword(s):  
Cyclic Amp ◽  
Trabecular Bone ◽  
Bone Cells ◽  
Synovial Cells ◽  
Human Trabecular Bone

Bradykinin stimulates prostaglandin E2 formation in isolated human osteoblast-like cells

1990 ◽  
Vol 10 (1) ◽  
pp. 121-126 ◽  
Author(s):  
Östen Ljunggren ◽  
Jan Rosenquist ◽  
Maria Ransjö ◽  
Ulf H. Lerner
Keyword(s):  
Parathyroid Hormone ◽  
Cyclic Amp ◽  
Prostaglandin E2 ◽  
Trabecular Bone ◽  
Human Osteoblast ◽  
Human Osteoblasts ◽  
Human Trabecular Bone ◽  
Stimulation Of ◽  
In Cells

The effect of bradykinin on prostaglandin E2 formation in cells from human trabecular bone has been studied. The cells responded to parathyroid hormone with enhanced cyclic AMP formation and were growing as cuboidal-shaped, osteoblast-like cells. In these isolated human osteoblast-like cells, bradykinin (1 μmol/l) caused a rapid (5 min) stimulation of prostaglandin E2 formation. This finding indicates that human osteoblasts are equipped with receptors for bradykinin linked to an increase in prostaglandin formation.

scholarly journals Human Trabecular Bone Cells Are Able to Express Both Osteoblastic and Adipocytic Phenotype: Implications for Osteopenic Disorders

1998 ◽  
Vol 13 (3) ◽  
pp. 371-382 ◽  
Author(s):  
Mark E. Nuttall ◽  
Amanda J. Patton ◽  
Diane L. Olivera ◽  
Daniel P. Nadeau ◽  
Maxine Gowen
Keyword(s):  
Trabecular Bone ◽  
Bone Cells ◽  
Human Trabecular Bone

Age-related changes in resorption cavity characteristics in human trabecular bone

1991 ◽  
Vol 1 (4) ◽  
pp. 257-261 ◽  
Author(s):  
P. I. Croucher ◽  
N. J. Garrahan ◽  
R. W. E. Mellish ◽  
Juliette E. Compston
Keyword(s):  
Trabecular Bone ◽  
Human Trabecular Bone ◽  
Age Related ◽  
Cavity Characteristics ◽  
Age Related Changes

scholarly journals Biaxial Normal Strength Behavior in the Axial-Transverse Plane for Human Trabecular Bone—Effects of Bone Volume Fraction, Microarchitecture, and Anisotropy

2013 ◽  
Vol 135 (12) ◽  
Author(s):  
Arnav Sanyal ◽  
Tony M. Keaveny
Keyword(s):  
Trabecular Bone ◽  
Volume Fraction ◽  
Elastic Anisotropy ◽  
Bone Volume ◽  
Transverse Plane ◽  
Mechanical Anisotropy ◽  
Bone Volume Fraction ◽  
Human Trabecular Bone ◽  
Strength Behavior ◽  
Normal Strength

The biaxial failure behavior of the human trabecular bone, which has potential relevance both for fall and gait loading conditions, is not well understood, particularly for low-density bone, which can display considerable mechanical anisotropy. Addressing this issue, we investigated the biaxial normal strength behavior and the underlying failure mechanisms for human trabecular bone displaying a wide range of bone volume fraction (0.06–0.34) and elastic anisotropy. Micro-computed tomography (CT)-based nonlinear finite element analysis was used to simulate biaxial failure in 15 specimens (5 mm cubes), spanning the complete biaxial normal stress failure space in the axial-transverse plane. The specimens, treated as approximately transversely isotropic, were loaded in the principal material orientation. We found that the biaxial stress yield surface was well characterized by the superposition of two ellipses—one each for yield failure in the longitudinal and transverse loading directions—and the size, shape, and orientation of which depended on bone volume fraction and elastic anisotropy. However, when normalized by the uniaxial tensile and compressive strengths in the longitudinal and transverse directions, all of which depended on bone volume fraction, microarchitecture, and mechanical anisotropy, the resulting normalized biaxial strength behavior was well described by a single pair of (longitudinal and transverse) ellipses, with little interspecimen variation. Taken together, these results indicate that the role of bone volume fraction, microarchitecture, and mechanical anisotropy is mostly accounted for in determining the uniaxial strength behavior and the effect of these parameters on the axial-transverse biaxial normal strength behavior per se is minor.

scholarly journals Development of a Crushable Foam Model for Human Trabecular Bone

2021 ◽  
Author(s):  
Navid Soltanihafshejani ◽  
Thom Bitter ◽  
Dennis Janssen ◽  
Nico Verdonschot
Keyword(s):  
Trabecular Bone ◽  
Human Trabecular Bone ◽  
Foam Model

TEM analysis of the nanostructure of normal and osteoporotic human trabecular bone

Bone ◽  
2003 ◽  
Vol 33 (3) ◽  
pp. 270-282 ◽  
Author(s):  
Matthew A Rubin ◽  
Iwona Jasiuk ◽  
Jeannette Taylor ◽  
Janet Rubin ◽  
Timothy Ganey ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Tem Analysis ◽  
Human Trabecular Bone
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