Age-related changes in resorption cavity characteristics in human trabecular bone

1991 ◽  
Vol 1 (4) ◽  
pp. 257-261 ◽  
Author(s):  
P. I. Croucher ◽  
N. J. Garrahan ◽  
R. W. E. Mellish ◽  
Juliette E. Compston
2011 ◽  
Vol 44 (12) ◽  
pp. 2279-2285 ◽  
Author(s):  
Jessica O. Green ◽  
Srinidhi Nagaraja ◽  
Tamim Diab ◽  
Brani Vidakovic ◽  
Robert E. Guldberg

2001 ◽  
Vol 42 (1) ◽  
pp. 15-19 ◽  
Author(s):  
M. Tanno ◽  
T. Horiuchi ◽  
I. Nakajima ◽  
S. Maeda ◽  
M. Igarashi ◽  
...  

2000 ◽  
Author(s):  
Oscar C. Yeh ◽  
Tony M. Keaveny

Abstract Relatively little is known about the inelastic properties of trabecular hard tissue. In cortical tissue, age-related changes in mechanical properties were primarily observed in the postyield regime [1, 2]. Most notably, the ultimate strain was found to decrease by 9% per decade [1]. If similar changes in inelastic properties exist in trabecular tissue, there could be implications for the damage behavior of trabecular bone at the whole specimen “apparent” level. Understanding the role of these inelastic properties may help researchers identify which properties of trabecular tissue are vital to characterize and may improve understanding of age-related increases in skeletal fragility.


2001 ◽  
Vol 42 (1) ◽  
pp. 15-19 ◽  
Author(s):  
M. Tanno ◽  
T. Horiuchi ◽  
I. Nakajima ◽  
S. Maeda ◽  
M. Igarashi ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Juliet Compston

Histomorphometric studies of the age-related changes in bone remodelling and structure in men are relatively sparse and mainly limited to the iliac crest. The available data indicate that loss of trabecular bone is predominantly due to decreased formation at the level of individual bone remodelling units and that an increase in remodelling rate does not play a major role. The main structural consequence of the changes in bone remodelling is trabecular thinning. In cortical bone, an age-related reduction in cortical width and increase in porosity have been demonstrated at several skeletal sites. However, the alterations in bone remodelling responsible for these changes remain to be established.


Author(s):  
Xiaowei S. Liu ◽  
X. Henry Zhang ◽  
Paul Sajda ◽  
Punam K. Saha ◽  
Felix W. Wehrli ◽  
...  

Osteoporosis is an age-related disease characterized by low bone mass and architectural deterioration. Other than bone volume fraction (BV/TV), microarchitecture of trabecular bone, such as trabecular type (rods or plates), connectivity, and orientation of the trabecular network is also believed to be important in governing the mechanical properties of trabecular bone. A recent study [1] showed that the microarchitecture alone affects elastic moduli of trabecular bone and, further, that trabecular plates make a far greater contribution than rods. In human vertebral trabecular bone, the roles of transverse vs. vertical rods in conferring mechanical properties of trabecular bone have been debated [2, 3]. It has been suggested that the role of transverse trabecular rod is critical in determining elastic modulus of vertebral trabecular bone. However, without explicit classifications of trabecular type, or orientation assessment at an individual trabecula level, it is not possible yet to test this hypothesis in human trabecular bone samples despite the development of three-dimensional (3D) micro computed tomography (μCT) and μCT based finite element (FE) models of human trabecular bone. With the newly developed technique of complete volumetric decomposition and individual trabecula based orientation analyses [4], now it is possible to quantitatively examine the contributions of trabecular rods of various orientations in the elastic properties of vertebral trabecular bone.


2012 ◽  
Vol 60 (3) ◽  
pp. 205-212 ◽  
Author(s):  
Anna Charuta ◽  
Małgorzata Dzierzęcka ◽  
Edward Czerwiński ◽  
Ross Gordon Cooper ◽  
Jarosław Olav Horbańczuk

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