scholarly journals Localization of gold in synovial membrane of rheumatoid arthritis treated with sodium aurothiomalate. Studies by electron microscope and electron probe x-ray microanalysis.

1977 ◽  
Vol 36 (3) ◽  
pp. 209-215 ◽  
Author(s):  
H Nakamura ◽  
M Igarashi
Keyword(s):  
Rheumatoid Arthritis ◽  
Electron Microscope ◽  
Synovial Membrane ◽  
Electron Probe ◽  
Sodium Aurothiomalate ◽  
X Ray

Electron probe X-ray analysis of siderosomes in the rabbit haemarthrotic synovial membrane

1976 ◽  
Vol 22 (1) ◽  
pp. 135-142 ◽  
Author(s):  
F. N. Ghadially ◽  
J. -M. A. Lalonde ◽  
A. F. Oryschak
Keyword(s):  
Synovial Membrane ◽  
Electron Probe ◽  
X Ray

Compositional imaging in the Electron Microscope

1991 ◽  
Vol 49 ◽  
pp. 2-3
Author(s):  
C. E. Lyman
Keyword(s):  
Electron Microscopy ◽  
Electron Beam ◽  
Electron Microscope ◽  
Data Collection ◽  
Electron Probe ◽  
Compositional Data ◽  
Fine Scale ◽  
Bulk Specimen ◽  
Beam Position ◽  
X Ray

Imaging of elemental distributions on a fine scale is one of the triumphs of electron microscopy. Compositional imaging frees the operator from the necessity of making decisions about which features contain the elements of interest. Elements in unexpected locations, or in unexpected association with other elements, may be found easily without operator bias as to where to locate the electron probe for compositional data collection. This technique may be applied to bulk or thin specimens using a variety of composition-sensitive signals as shown in Figure 1.Cosslett and Duncumb obtained the first such compositional image in an electron microprobe modified to scan the electron beam and collect a characteristic x-ray signal as a function of beam position. Early images of this type were called x-ray “dot maps” and provided a qualitative indication of the location of elements on a flat polished bulk specimen to a spatial resolution of about 1 μm.

Combined Plasma-Microincineration, Electron Microscopy And Electron Probe Microanalysis For Fine Localization of Biological Mineral Substances

1973 ◽  
Vol 31 ◽  
pp. 334-335 ◽  
Author(s):  
Richard S. Thomas ◽  
Mabel I. Corlett
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Electron Probe ◽  
Oxygen Plasma ◽  
Chemical Nature ◽  
The Other ◽  
X Ray ◽  
Transmission Electron ◽  
Mineral Substances ◽  
Fine Localization

Ash patterns produced by oxygen plasma microincineration(OPM) of thin-sectioned biological materials and examined with the transmission electron microscope (TEM) can show unambiguously the distribution of mineral substances in the specimen with resolutions down to 100 Å. The chemical nature of the mineral is not demonstrated, however. Electron-probe X-ray microanalysis (EXM), on the other hand, can determine precisely the nature of the mineral in ashgd or unashed sections but its spatial resolution is limited to 1000-10,000 A at best. Also its sensitivity of analysis on unashed specimens is limited by intolerance of the specimen to high beam intensities. Using both TEM and EXM together on ash patterns of suitable specimens can overcome their independent spatial and chemical limitations. Furthermore, use of OPM produces a highly stable mineral specimen for EXM, thereby improving sensitivity.

The Analysis of Particles With Energy Dispersive X-Ray Spectroscopy (EDS)

1998 ◽  
Vol 4 (S2) ◽  
pp. 184-185
Author(s):  
J. A. Small ◽  
J. A. Armstrong ◽  
D. S. Bright ◽  
B. B. Thorne
Keyword(s):  
Electron Microscope ◽  
Elemental Analysis ◽  
Electron Probe ◽  
Initial Particle ◽  
X Ray ◽  
Transmission Electron ◽  
Analytical Electron ◽  
Analytical Electron Microscope ◽  
The Individual ◽  
Individual Particles

The addition of the Si-Li detector to the electron probe, the scanning electron microscope, and more recently the transmission electron microscope (resulting in the analytical electron microscope) has made it possible to obtain elemental analysis on individual “particles” with dimensions less than 1 nm using EDS. Although some initial particle studies on micrometer-sized particles were done on the electron probe using wavelength dispersive spectrometers, WDS, the variability and complexity of many particle compositions coupled with the high currents necessary for WDS made elemental analysis of particles by WDS difficult at best. In addition, the use of multiple spectrometers, each with a different view of the particle and therefore different particle geometry as shown in Fig. 1, limited the quantitative capabilities of the technique. With the introduction of the Si-Li detector, there was only one spectrometer with a single geometry resulting in the development of various procedures for obtaining quantitative elemental analysis of the individual particles.

X-Ray Microanalysis of Al/Zr Multilayers in the Transmission Electron Microscope

1997 ◽  
Vol 472 ◽  
Author(s):  
M. A. Wall ◽  
T. W. Barbee ◽  
J. Bentley
Keyword(s):  
Electron Microscope ◽  
Transmission Electron Microscope ◽  
Electron Probe ◽  
Nanometer Scale ◽  
Line Profiles ◽  
Electron Microscopic ◽  
X Ray ◽  
Transmission Electron ◽  
Interface Layers

ABSTRACTA one-nanometer scale transmission electron microscope electron probe X-ray microanalysis characterization of as-deposited and annealed aluminum - 11.5 at.% zirconium multilayer samples in cross-section synthesized by magnetron sputtering is reported on here. Composition line profiles were acquired across Zr layers in as-deposited material and samples isochronnally annealed in a differential scanning calorimeter to temperatures of 290°C and 485°C. A spatial resolution of approximaty 1.5 to 2.0 nm was achieved in these experiments and will be improved by deconvoluti on of the instrumental electron probe function from the data. The as-deposited structure consisted of crystalline Al and Zr layers with thin amorphous layers at the Al/Zr interfaces. The amorphous interface layers increased in thickness upon annealing to 290°C. Additionally, at 290”C a metastable cubic alloy forms at the Zr deposited on Al interface. Upon heating to 485°C a multilayer of Al and metastable cubic AlxZr1-x phase is formed. The electron microscopic experimental technique, observations and data analysis will be discussed as applied to these multilayered materials.

Electron probe X-ray microanalysis of human skeletal muscle involved in rheumatoid arthritis

1978 ◽  
Vol 57 (1) ◽  
pp. 1-8 ◽  
Author(s):  
R. Wr�blewski ◽  
W. Gremski ◽  
R. Nordemar ◽  
L. Edstr�m
Keyword(s):  
Rheumatoid Arthritis ◽  
Skeletal Muscle ◽  
Electron Probe ◽  
Human Skeletal Muscle ◽  
X Ray

A quantitative investigation of thin specimen X-ray spectra in the TEM

1978 ◽  
Vol 36 (1) ◽  
pp. 550-551
Author(s):  
B.W. Robertson ◽  
J.N. Chapman ◽  
W.A.P. Nicholson ◽  
R.P. Ferrier
Keyword(s):  
Electron Microscope ◽  
Electron Probe ◽  
X Rays ◽  
Quantitative Investigation ◽  
Solid Materials ◽  
Thin Specimen ◽  
X Ray ◽  
Transmission Electron ◽  
Extraneous Radiation ◽  
The Continuum

In electron probe x-ray microanalysis, the observed x-ray spectra are degraded by the presence of both characteristic and bremsstrahlung x-rays from the regions of the specimen which are not under analysis and from the solid materials near the specimen. These x-rays are generated by electrons scattered from the probe by the specimen and by stray electrons originally outside the probe. The extraneous bremsstrahlung x-rays form a component of the observed continuum which is only indirectly dependent on the nature of the specimen. This effect is particularly undesirable in the analysis of thin biological specimens in the transmission electron microscope since the continuum level is commonly used in quantitative analysis as a measure of specimen mass thickness. Experiments have therefore been performed to investigate the magnitude of the extraneous radiation and to evaluate the success of attempts to reduce it. These have been detailed elsewhere (Nicholson et al. 1977).

Ultrastructure of the haemophilic synovial membrane and electron-probe X-ray analysis of haemosiderin

1976 ◽  
Vol 120 (4) ◽  
pp. 201-208 ◽  
Author(s):  
F. N. Ghadially ◽  
R. L. Ailsby ◽  
N. K. Yong
Keyword(s):  
Synovial Membrane ◽  
Electron Probe ◽  
X Ray
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