Do pakistani babies have more congenital heart defects? Preliminary findings from our birth cohort study

2011 ◽  
Vol 96 (Supplement 1) ◽  
pp. A35-A35 ◽  
Author(s):  
P. Agadoorappa ◽  
S. Oddie ◽  
N. Pawson ◽  
E. Sheridon
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Birth Cohort Study

scholarly journals Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature

2008 ◽  
Vol 168 (9) ◽  
pp. 1081-1090 ◽  
Author(s):  
Klaartje van Engelen ◽  
Johannes H. M. Merks ◽  
Jan Lam ◽  
Leontien C. M. Kremer ◽  
Manouk Backes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Review Of Literature

scholarly journals Intake of sucrose-sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in offspring: a Norwegian pregnancy cohort study

2019 ◽  
Vol 34 (4) ◽  
pp. 383-396 ◽  
Author(s):  
Maria T. Grønning Dale ◽  
Per Magnus ◽  
Elisabeth Leirgul ◽  
Henrik Holmstrøm ◽  
Håkon K. Gjessing ◽  
...  
Keyword(s):  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Pregnancy Cohort

scholarly journals Maternal psychological distress, education, household income, and congenital heart defects: a prospective cohort study from the Japan environment and children’s study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yasuaki Saijo ◽  
Eiji Yoshioka ◽  
Yukihiro Sato ◽  
Hiroshi Azuma ◽  
Yusuke Tanahashi ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Psychological Distress ◽  
Congenital Heart Defects ◽  
Household Income ◽  
Prospective Cohort ◽  
Congenital Heart ◽  
Maternal Education ◽  
Heart Defects ◽  
Maternal Psychological Distress

Abstract Background The influence of maternal psychological distress on infant congenital heart defects (CHDs) has not been thoroughly investigated. Furthermore, there have been no reports on the combined effect of maternal psychological distress and socioeconomic status on infant CHDs. This study aimed to examine whether maternal psychological distress, socioeconomic status, and their combinations were associated with CHD. Methods We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women between 2011 and 2014. Maternal psychological distress was evaluated using the Kessler Psychological Distress Scale in the first trimester, while maternal education and household income were evaluated in the second and third trimesters. The outcome of infant CHD was determined using the medical records at 1 month of age and/or at birth. Crude- and confounder-adjusted logistic regression analyses were performed to evaluate the association between maternal psychological distress and education and household income on infant CHD. Results A total of 93,643 pairs of mothers and infants were analyzed, with 1.1% of infants having CHDs. Maternal psychological distress had a significantly higher odds ratio in the crude analysis but not in the adjusted analysis, while maternal education and household income were statistically insignificant. In the analysis of the combination variable of lowest education and psychological distress, the P for trend was statistically significant in the crude and multivariate model excluding anti-depressant medication, but the significance disappeared in the full model (P = 0.050). Conclusions The combination of maternal psychological distress and lower education may be a possible indicator of infant CHD.

scholarly journals Congenital heart defects of fetus after maternal exposure to organic and inorganic environmental factors: a cohort study

Oncotarget ◽  
2017 ◽  
Vol 8 (59) ◽  
pp. 100717-100723
Author(s):  
Wei Gong ◽  
Qianhong Liang ◽  
Dongming Zheng ◽  
Risheng Zhong ◽  
Yunjie Wen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Environmental Factors ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Maternal Exposure

scholarly journals VP33.03: The diagnostic yield of prenatal genomic testing in congenital heart defects: a cohort study

2020 ◽  
Vol 56 (S1) ◽  
pp. 194-194
Author(s):  
F. Mone ◽  
B. Stott ◽  
S. Hamilton ◽  
A.N. Seale ◽  
E. Quinlan‐Jones ◽  
...  
Keyword(s):  
Cohort Study ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Diagnostic Yield ◽  
Heart Defects ◽  
Genomic Testing

scholarly journals Mortality with congenital heart defects in England and Wales, 1959–2009: exploring technological change through period and birth cohort analysis

2012 ◽  
Vol 97 (10) ◽  
pp. 861-865 ◽  
Author(s):  
Rachel L Knowles ◽  
Catherine Bull ◽  
Christopher Wren ◽  
Carol Dezateux
Keyword(s):  
Intensive Care ◽  
Birth Cohort ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Cohort Analysis ◽  
Age Groups ◽  
Birth Cohorts ◽  
Death Rates ◽  
England And Wales

BackgroundTechnological advances in surgery, intensive care and medical support have led to substantial decrease in mortality for children with congenital heart defects (CHDs) over the last 50 years.MethodsUsing routinely-collected mortality and population data for England and Wales from 1959 to 2009, the authors investigated age, period and birth cohort trends in child mortality attributable to CHDs.ResultsThe total number of deaths with CHDs at all ages between 1959 and 2009 was 61 903 (33 929 (55%) males). Absolute numbers of CHD-related deaths in children (under age 15 years) fell from 1460 in 1959 to 154 in 2009. Infants (aged under 1 year) comprised over 60% of all deaths due to CHD during the 5-year period 1959–1963, but this fell to 22% by 2004–2008. Age-standardised death rates have declined for both sexes but, despite narrowing sex differences, males continue to have higher death rates. Successive birth cohorts have experienced improved death rates in the first year of life; however, declining mortality across all age-groups has only been observed for birth cohorts originating after 1989. Poisson regression modelling predicts continuing generational decline in mortality.ConclusionsDeath rates attributable to CHDs have fallen dramatically with advances in paediatric cardiac surgery and intensive care, largely due to decreased mortality in infants aged under 1 year. Initially, mortality in later childhood rose as infant deaths fell, suggesting death was delayed beyond infancy. Children born within the last 20 years experienced lower mortality throughout childhood.

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