scholarly journals Protein metabolism in preterm infants with particular reference to intrauterine growth restriction

2007 ◽  
Vol 92 (4) ◽  
pp. F315-F319 ◽  
Author(s):  
H A de Boo ◽  
J E Harding
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Caroline Ayres ◽  
Marilyn Agranonik ◽  
André Krumel Portella ◽  
Françoise Filion ◽  
Celeste C. Johnston ◽  
...  

Intrauterine growth restriction is associated with increased risk for adult metabolic syndrome and cardiovascular disease, which seems to be related to altered food preferences in these individuals later in life. In this study, we sought to understand whether intrauterine growth leads to fetal programming of the hedonic responses to sweet. Sixteen 1-day-old preterm infants received 24% sucrose solution or water and the taste reactivity was filmed and analyzed. Spearman correlation demonstrated a positive correlation between fetal growth and the hedonic response to the sweet solution in the first 15 seconds after the offer (r=0.864,P=0.001), without correlation when the solution given is water (r=0.314,P=0.455). In fact, the more intense the intrauterine growth restriction, the lower the frequency of the hedonic response observed. IUGR is strongly correlated with the hedonic response to a sweet solution in the first day of life in preterm infants. This is the first evidence in humans to demonstrate that the hedonic response to sweet taste is programmed very early during the fetal life by the degree of intrauterine growth. The altered hedonic response at birth and subsequent differential food preference may contribute to the increased risk of obesity and related disorders in adulthood in intrauterine growth-restricted individuals.


2015 ◽  
Vol 167 (5) ◽  
pp. 975-981.e2 ◽  
Author(s):  
Isabelle Guellec ◽  
Stephane Marret ◽  
Olivier Baud ◽  
Gilles Cambonie ◽  
Alexandre Lapillonne ◽  
...  

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Masato Kantake ◽  
Naho Ikeda ◽  
Hirofumi Nakaoka ◽  
Natsuki Ohkawa ◽  
Toshitaka Tanaka ◽  
...  

2015 ◽  
Vol 29 (14) ◽  
pp. 2268-2274 ◽  
Author(s):  
Júlia Candel Pau ◽  
Josep Perapoch López ◽  
Félix Castillo Salinas ◽  
Olga Sánchez Garcia ◽  
Santiago Pérez Hoyos ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Nehal M El-Raggal ◽  
Maii M Nawara ◽  
Amani M Abd El-Ghani ◽  
Mary E Zareif ◽  
Basma M Shehata

Abstract Background Intrauterine growth restriction (IUGR) is one of the causes of perinatal mortality and morbidity. It is the failure of the fetus to achieve intrinsic growth potential. Since IUGR neonates are more likely to suffer complications including perinatal asphyxia, cold stress, hypoglycemia, hypocalcaemia, hyperbilirubinemia, feed intolerance, NEC, sepsis and even mortality. So, it is important that these infants are identified and managed appropriately at birth. Purpose The present study aims to determine the possible association between cord blood ischemia-modified albumin (IMA) levels and intrauterine growth restriction (IUGR) in preterm infants with or without complicated gestations. Patients and Method Eighty mothers and their preterm neonates (<37 weeks’ gestation) identified in 2 groups according to antenatal ultrasound: a group with prospective antenatal diagnosis of IUGR and the other group with normal fetal development, after consideration of inclusion and exclusion criteria. Cord blood Albumin and Ischemia modified albumin were estimated by double-antibody sandwich Enzyme-Linked Immunosorbent Assay (ELISA). Results Cord blood IMA was significantly higher in IUGR group compared to control group. Consequently, albumin level was significantly lower in IUGR group compared to other group. IMA was inversely correlation with Hb level and albumin level was inversely correlated with liver function tests (ALT and AST). Conclusion There is a positive association between IMA level and IUGR. This sent a message that combined antenatal ultrasound and serum IMA is a better predictor of intrauterine growth restriction and subsequent better care of neonates with IUGR.


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