Differential effects of intrauterine growth restriction on brain structure and development in preterm infants: A magnetic resonance imaging study

2011 ◽  
Vol 1382 ◽  
pp. 98-108 ◽  
Author(s):  
Nelly Padilla ◽  
Carles Falcón ◽  
Magdalena Sanz-Cortés ◽  
Francesc Figueras ◽  
Núria Bargallo ◽  
...  
2006 ◽  
Vol 254-255 ◽  
pp. 163-171 ◽  
Author(s):  
Stéphane V. Sizonenko ◽  
Cristina Borradori-Tolsa ◽  
Delphine M. Vauthay ◽  
Gregory Lodygensky ◽  
François Lazeyras ◽  
...  

2012 ◽  
Vol 88 ◽  
pp. S35-S40 ◽  
Author(s):  
Mellisa S. Damodaram ◽  
Lisa Story ◽  
Elisanda Eixarch ◽  
Prachi Patkee ◽  
Abhilasha Patel ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Serafina Perrone ◽  
Antonino Santacroce ◽  
Giuseppe de Bernardo ◽  
Maria Gabriella Alagna ◽  
Salvatore Francesco Carbone ◽  
...  

Objective. Intrauterine growth restriction (IUGR) is a major cause of late stillbirth, though not all compromised babies remain small or are considered growth restricted as pregnancy progresses. Fetal Magnetic Resonance Imaging (f-MRI) represents a second-line tool to study pregnancies with IUGR fetuses. The aim of our study was to evaluate the usefulness of f-MRI on predicting fetal growth and the offspring’s perinatal respiratory outcome. Design. All f-MRI performed between 2014 and 2016 in Siena were analysed. Pregnancies with IUGR (Study group (SG)) were recruited together with a control population (Control group (CG)), coupled for gestational age (GA) at the time of f-MRI (mean GA 31 wks). Neonatal information was collected. The f-MRI protocol consisted of T2w images. Six regions of interest (ROI) were placed as follows: 2 on the lung, 2 on the liver, and 2 on the amniotic fluid. The signal intensities (SI) of each ROI were measured. The SI lung to liver ratio (SI lung/liver) and SI lung to amniotic fluid ratio (SI lung/amniotic fluid) were obtained for each fetus. Each ratio was compared between SG and CG. Therefore, SG was divided into two subgroups: adequate and small for gestational age (AGA and SGA) newborns. All measurements were related to offspring’s perinatal respiratory outcome. Results. SI lung/liver was linearly related with GA at the time of f-MRI and with EFW. SI lung/amniotic fluid was significantly higher in SG than in CG (p=0,014). In contrast, among SG, lower values of SI lung/amniotic fluid were found in the SGA compared to AGA (p=0,036). The days of oxygen supply were higher in the SGA subgroup than in the AGA subgroup (p=0,028). Conclusions. SI lung/liver increases with fetal lung maturation and appears to be useful to estimate intrauterine fetal growth. SI lung/amniotic fluid seems to be a reliable predictive index to distinguish the IUGR fetuses that can recover their growth from those that were born SGA. f-MRI represents a promising frontier to predict IUGR fetus outcome, thus contributing to ameliorate the perinatal management.


2016 ◽  
Vol 204 ◽  
pp. 219-225 ◽  
Author(s):  
Charlotte L. Allan ◽  
Claire E. Sexton ◽  
Nicola Filippini ◽  
Anya Topiwala ◽  
Abda Mahmood ◽  
...  

2012 ◽  
Vol 71 (10) ◽  
pp. 855-863 ◽  
Author(s):  
Anthony C. Vernon ◽  
Sridhar Natesan ◽  
William R. Crum ◽  
Jonathan D. Cooper ◽  
Michel Modo ◽  
...  

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