Syntheses of New Triethylene Glycol Bis(alkyl Phosphate)s as Potential Complexing Agents

2001 ◽  
Vol 66 (4) ◽  
pp. 621-630 ◽  
Author(s):  
Věra Novoměstská ◽  
Eckhard Herrmann ◽  
Přemysl Lubal ◽  
Jiří Příhoda
Keyword(s):  
Ir Spectroscopy ◽  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Metal Cations ◽  
Triethylene Glycol ◽  
Complexing Agents ◽  
H Nmr ◽  
Maldi Tof ◽  
Alkyl Phosphate ◽  
C Nmr

A series of triethylene glycol bis(alkyl phosphate)s HO(RO)P(O)(OCH2CH2)3OP(O)(OR)OH 4 (R = octyl (4a), 1-methylheptyl (4b), 2-ethylhexyl (4c), nonyl (4d), decyl (4e), dodecyl (4f), hexadecyl (4g), octadecyl (4h)) has been synthesized with the expectation that these compounds could be effective complexing and/or extraction agents for metal cations. The compounds were characterized by 31P NMR, 1H NMR, 13C NMR and IR spectroscopy, MALDI-TOF mass spectroscopy and elemental analysis.

Synthesis, X-ray Characterization and Antimicrobial Activity of (3-(4-bromophenyl)oxiran-2-yl)(2,4-dichlorophenyl)methanone

2018 ◽  
Vol 15 (2) ◽  
pp. 521-524
Author(s):  
Mona A. Alsafi ◽  
Eman M. Flefel ◽  
Nermeen S. Abbas ◽  
Abd El-Galil E. Amr ◽  
Hazem A. Ghabbour
Keyword(s):  
Hydrogen Peroxide ◽  
Nuclear Magnetic Resonance ◽  
Antimicrobial Activity ◽  
Magnetic Resonance ◽  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Fusidic Acid ◽  
X Ray ◽  
H Nmr ◽  
C Nmr

(3-(4-bromophenyl)oxiran-2-yl)(2,4-dichlorophenyl)methanone 2 was synthesized via treating of 3-(4-bromophenyl)-1-(2,4-dichlorophenyl) prop-2-en-1-one 1 with hydrogen peroxide in the presence of sodium hydroxide in a mixture from acetone and methanol with stirring. The structure and purity of the synthesized product was confirmed by elemental analysis, IR, nuclear magnetic resonance (1H NMR and 13C NMR), mass spectroscopy and X-ray single crystal. The obtained compound 2 was screened as antimicrobial activity compared to Streptomycin and Fusidic acid as reference drugs.

A convenient synthesis of phthalocyanines bearing four methyl 4-hexyloxyphenyl-2-phenoxy acrylate functionalities

2009 ◽  
Vol 13 (06) ◽  
pp. 739-746 ◽  
Author(s):  
A. Aslı Esenpınar ◽  
A. Rıza Özkaya ◽  
Mustafa Bulut
Keyword(s):  
Hydroxy Group ◽  
Elemental Analysis ◽  
Lactone Ring ◽  
Redox Behavior ◽  
Synthetic Pathway ◽  
H Nmr ◽  
Maldi Tof ◽  
Convenient Synthesis ◽  
Vis Spectroscopy ◽  
C Nmr

A novel synthetic pathway for the preparation of a new phthalonitrile derivative, methyl (E)-3-[2-(3,4-dicyanophenoxy)-4-(hexyloxy)phenyl]acrylate (3), based on the opening of the lactone ring of 7-hexyloxycoumarin (2H-1-benzopyrane-2-one, 2H-chromen-2-one) and ether formation of the formed hydroxy group with 4-nitrophthalonitrile, is presented. Cyclotetramerization of this dinitrile in 2-N,N-dimethylaminoethanol gives the desired Zn(II) , Co(II) and Cu(II) phthalocyanines (4, 5 and 6) with four methyl 4-hexyloxy-2-phenoxy acrylate moiety on periphery. The complexes are characterized by IR, elemental analysis, 1 H NMR, 13 C NMR MALDI-TOF and UV-vis spectroscopy. The redox behavior of the complexes are also discussed.

scholarly journals Synthesis, Characterization, and Electrochemical Behaviour of Cobalt(II) and Nickel(II) Complexes with N2O2 Chelating Ligand 4,4′-(Biphenyl-4,4′-diyldinitrilo)dipentan-2-one

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Lakhdar Sibous ◽  
Embarek Bentouhami ◽  
Mustayeen Ahmed Khan
Keyword(s):  
Schiff Base ◽  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
Electrochemical Behaviour ◽  
Absolute Ethanol ◽  
Molar Ratio ◽  
H Nmr ◽  
Chelating Ligand ◽  
Metal Ligand

4,4′-Diaminobiphenyl reacts with 2,4-pentanedione in absolute ethanol in a molar ratio 1 : 2 to form mainly the product of [1 + 2] condensation, 4,4′-(biphenyl-4,4′-diyldinitrilo)dipentan-2-one (H2L). The Schiff base was used as tetradentate chelating ligand to coordinate CoII and NiII chlorides leading to complexes where the ratio of metal ligand was found to be 2 : 1 or 2 : 2. All the synthesized products were characterized by elemental analysis, infrared, electronic, and mass spectroscopy, 1H NMR, and DSC. The electrochemical behaviour of the ligand and its complexes in DMF is also investigated.

Synthesis, Characterization and Complexation Studies with K + and Ca2+ Cations of trans-1.2-Cyclohexanedioxydiacetamides

1988 ◽  
Vol 43 (2) ◽  
pp. 165-170 ◽  
Author(s):  
Whei Oh Lin ◽  
Maria C. B. V. de Souza ◽  
Helmut G. Alt
Keyword(s):  
Nmr Spectroscopy ◽  
Mass Spectroscopy ◽  
H Nmr ◽  
Coordination Sites ◽  
Complexation Studies ◽  
Ir And Nmr Spectroscopy ◽  
Elemental Analyses ◽  
C Nmr

The synthesis of trans-1.2-cyclohexanedioxydiacetamides starting with trans-1.2-cyclohexane-diol is described. Eleven of these compounds are characterized by IR, 1H NMR, 13C NMR and mass spectroscopy as well as elemental analyses. Most of these compounds are suitable ionophors for the cations K+ and Ca2+. The coordination sites of these ligands in the 1:2 complexes were determined by IR and NMR spectroscopy

scholarly journals SYNTHESIS AND STRUCTURAL ELUCIDATION OF AMINO ACETYLENIC AND THIOCARBAMATES DERIVATIVES FOR 2-MERCAPTOBENZOTHIAZOLE AS ANTIMICROBIAL AGENTS

2017 ◽  
Vol 9 (2) ◽  
pp. 192
Author(s):  
Aseel Alsarahni ◽  
Zuhair Muhi Eldeen ◽  
Elham Al-kaissi ◽  
Ibrahim Al- Adham ◽  
Najah Al-muhtaseb
Keyword(s):  
Antimicrobial Activity ◽  
Elemental Analysis ◽  
Antimicrobial Agents ◽  
Diffusion Method ◽  
Benzothiazole Derivatives ◽  
H Nmr ◽  
Ft Ir ◽  
Potential Antimicrobial Activity ◽  
C Nmr

<p><strong>Objective: </strong>To design and synthesize amino acetylenic and thiocarbonate of 2-mercapto-1,3-benthiazoles as potential antimicrobial agents.</p><p><strong>Methods: </strong>A new series of 2-{[4-(t-amino-1-yl) but-2-yn-1-yl] sulfanyl}-1,3-benzothiazole derivatives (AZ1-AZ6), and S-1,3-benzothiazol-2-yl-O-alkyl carbonothioate derivatives were synthesised, with the aim that the target compounds show new and potential antimicrobial activity. The elemental analysis was indicated by the EuroEA elemental analyzer, and biological characterization was via IR, <sup>1</sup>H-NMR, [13]C-NMR, DSC were determined with the aid of Bruker FT-IR and Varian 300 MHz spectrometer using DMSO-d<sub>6</sub> as a solvent.<em> </em><em>In vitro </em>antimicrobial activity, evaluation was done for the synthesised compounds, by agar diffusion method and broth dilution test. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) were determined. <em></em></p><p><strong>Results: </strong>The IR, <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, DSC and elemental analysis were consistent with the assigned structures. Compound of 2-{[4-(4-methylpiperazin-1-yl)but-2-yn-1-yl] sulfanyl}-1,3-benzothiazole (AZ1), 2-{[4-(2-methylpiperidin-1-yl)but-2-yn-1-yl]sulfanyl}-1,3-benzothiazole (AZ2), 2-{[4-(piperidin-1-yl) but-2-yn-1-yl]sulfanyl}-1, 3-benzothiazole (AZ6), S-1,3-benzothiazol-2-yl-O-ethyl carbonothioate (AZ7), and S-1,3-benzothiazol-2-yl-O-(2-methylpropyl) carbonothioate (AZ9) showed the highest antimicrobial activity against <em>Pseudomonas aeruginosa </em>(<em>P. aeruginosa</em>), AZ-9 demonstrated the highest antifungal activity against <em>Candida albicans </em>(<em>C. albicans</em>), with MIC of 31.25 µg/ml.</p><p><strong>Conclusion: </strong>These promising results promoted our interest to investigate other structural analogues for their antimicrobial activity further.</p>

[Zn(phen)2(CX3COO)]+, X = H orCl; Influence of X on the Coordination Mode of the Carboxylate Group (phen = 1,10-Phenanthroline)

2005 ◽  
Vol 60 (10) ◽  
pp. 1049-1053 ◽  
Author(s):  
Zeanab Talaei ◽  
Ali Morsali ◽  
Ali R. Mahjoub
Keyword(s):  
Nmr Spectroscopy ◽  
Elemental Analysis ◽  
Coordination Mode ◽  
Bidentate Ligand ◽  
Carboxylate Group ◽  
X Ray ◽  
X Ray Crystallography ◽  
H Nmr ◽  
Coordinate Geometry ◽  
C Nmr

Two new ZnII(phen)2 complexes with trichloroacetate and acetate anions, [Zn(phen)2(CCl3COO)- (H2O)](ClO4) and [Zn(phen)2(CH3COO)](ClO4), have been synthesized and characterized by elemental analysis, IR, 1H NMR, 13C NMR spectroscopy. The single crystal X-ray data of these compounds show the Zn atoms to have six-coordinate geometry. From IR spectra and X-ray crystallography it is established that the coordination of the COO− group is different for trichloroacetate and acetate. The former acts as a monodentate whereas the latter acts as a bidentate ligand.

Synthesis and Pharmacological Activities of Some New 2-[1-Heptyl-3-(4- methoxybenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]acetohydrazide Derivatives

2014 ◽  
Vol 69 (9-10) ◽  
pp. 969-981 ◽  
Author(s):  
Olcay Bekircan ◽  
Emre Mentese ◽  
Serdar Ulker
Keyword(s):  
Nmr Spectroscopy ◽  
Elemental Analysis ◽  
Lipase Activity ◽  
Spectral Studies ◽  
Antituberculosis Activity ◽  
Pharmacological Activities ◽  
Mass Spectral ◽  
H Nmr ◽  
Acetohydrazide Derivative ◽  
C Nmr

Abstract In the present investigation, the key intermediate acetohydrazide derivative 5 was synthesized starting from 3-(4-methoxybenzyl)-4-amino-4,5-dihydro-1,2,4-triazol-5-one (1) by a four-step reaction. Thiosemicarbazides 6a-f and arylidenehydrazide derivatives 8a-d were obtained from compound 5. The cyclization of compounds 6a-f in the presence of NaOH resulted in the formation of compounds 7a-f. The compounds were characterized by IR, 1H NMR, 13C NMR spectroscopy, elemental analysis and mass spectral studies. The compounds were tested for their anti-lipase, anti-α-glucosidase and anti-mycobacterial activities. Compounds 6b and 8c exhibited excellent anti-lipase activity, and compound 8d showed excellent anti-a-glucosidase activity. Compounds 3 and 4 exhibited good antituberculosis activity

scholarly journals Synthesis of cis, cis-1,3,5-trisubstituted cyclohexane based chelators with polyfunctional pendant arms

2005 ◽  
Vol 2005 (1) ◽  
pp. 43-45 ◽  
Author(s):  
Minati Baral ◽  
B.K. Kanungo ◽  
Peter Moore
Keyword(s):  
Schiff Base ◽  
Nmr Spectroscopy ◽  
Organic Compounds ◽  
Elemental Analysis ◽  
H Nmr ◽  
Benzenetricarboxylic Acid ◽  
New Compounds ◽  
Pendant Arms ◽  
C Nmr

Some novel organic compounds of the type: cis, cis-1,3,5-tris(X)cyclohexane, where X= –CONH(CH2)2NH2, –CONH(CH2)3NH2, –CONH(CH2)2NCH –C6H4OH, CONH(CH2)3NCHC6H4OH, which are expected to function as potential polydentate chelators have been synthesised from 1,3,5-benzenetricarboxylic acid through multi-steps reactions. 1,3,5-benzenetricarboxylic acid was reduced to cis, cis-1,3,5-tris(ethylcarboxylate)cyclohexane, which on reaction with excess of 1,2-diaminoethane and 1,2-diaminopropane afforded two new compounds. Condensation of the obtained derivatives with three equivalents of salicylaldehyde resulted the formation of two new Schiff base compounds. All the compounds were characterised by a combination of elemental analysis, mass, IR, UV-Vis, 1H NMR and 13C NMR spectroscopy.

ChemInform Abstract: Synthesis of New Triethylene Glycol Bis(alkyl phosphate)s as Potential Complexing Agents.

ChemInform ◽  
2010 ◽  
Vol 32 (39) ◽  
pp. no-no
Author(s):  
Vera Novomestska ◽  
Eckhard Herrmann ◽  
Premysl Lubal ◽  
Jiri Prihoda
Keyword(s):  
Triethylene Glycol ◽  
Complexing Agents ◽  
Alkyl Phosphate

Darstellung und Charakterisierung von 1.4- und 1.5-Dienkomplexen des Platins- Röntgenstrukturanalyse von Dichloro-2.5-diphenyl-1.5-hexadienplatin(II), Cl2Pt((C6H5)2C6H8) / Preparation and Characterization of 1,4- and 1,5-Diene Complexes of Platinum; X-ray Analysis of Dichloro-2,5-diphenyl-1,5-hexadiene Platinum(II), ((Cl2Pt(C6H5)2C6H8)

1980 ◽  
Vol 35 (7) ◽  
pp. 802-807 ◽  
Author(s):  
Michael Kopp ◽  
Luise R. Krauth ◽  
Richard Ratka ◽  
Klaus Weidenhammer ◽  
Manfred L. Ziegler
Keyword(s):  
Mass Spectroscopy ◽  
Elemental Analysis ◽  
X Ray ◽  
H Nmr ◽  
Ray Methods

The reaction of cis-(C6H5CN)2PtCl2 and Na2PtCl4 with the dienes 1,4-pentadiene and 2,5-diphenyl-1,5-hexadiene yields the species cis-(1,4-pentadiene) PtCl2 and cis-(2,5-diphenyl-1,5-hexadiene)PtCl2, respectively. The compounds have been fully characterized by elemental analysis, IR, 1H-NMR, mass spectroscopy and by X-ray methods

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