Formation of Polyelectrolyte Complexes

1993 ◽  
Vol 58 (4) ◽  
pp. 713-747 ◽  
Author(s):  
Jaroslav Mikulík ◽  
Zdeněk Vinklárek ◽  
Milan Vondruška
Keyword(s):  
Reaction Conditions ◽  
Polyelectrolyte Complexes ◽  
Molecular Parameters ◽  
Oppositely Charged

Polyelectrolyte complexes are intermacromolecular complexes, i.e. macromolecular compounds formed by interpolymeric reaction between oppositely charged polyelectrolytes. The effect of the molecular parameters and reaction conditions on the formation and structure of polyelectrolyte complexes is reviewed.

Exciton Transfer and Emergent Excitonic States in Oppositely-Charged Conjugated Polyelectrolyte Complexes

2016 ◽  
Vol 120 (31) ◽  
pp. 7767-7774 ◽  
Author(s):  
William R. Hollingsworth ◽  
Carmen Segura ◽  
Jonathan Balderrama ◽  
Nathaniel Lopez ◽  
Pamela Schleissner ◽  
...  
Keyword(s):  
Polyelectrolyte Complexes ◽  
Conjugated Polyelectrolyte ◽  
Exciton Transfer ◽  
Excitonic States ◽  
Oppositely Charged

scholarly journals On the Development of All-Cellulose Capsules by Vesicle-Templated Layer-by-Layer Assembly

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 589
Author(s):  
Alireza Eivazi ◽  
Bruno Medronho ◽  
Björn Lindman ◽  
Magnus Norgren
Keyword(s):  
Low Cost ◽  
Core Shell ◽  
Cellulose Derivatives ◽  
Layer By Layer ◽  
Reaction Conditions ◽  
Didodecyldimethylammonium Bromide ◽  
Shell Particles ◽  
Micrometer Scale ◽  
Oppositely Charged ◽  
Scale Deposition

Polymeric multilayer capsules formed by the Layer-by-Layer (LbL) technique are interesting candidates for the purposes of storage, encapsulation, and release of drugs and biomolecules for pharmaceutical and biomedical applications. In the current study, cellulose-based core-shell particles were developed via the LbL technique alternating two cellulose derivatives, anionic carboxymethylcellulose (CMC), and cationic quaternized hydroxyethylcellulose ethoxylate (QHECE), onto a cationic vesicular template made of didodecyldimethylammonium bromide (DDAB). The obtained capsules were characterized by dynamic light scattering (DLS), ζ potential measurements, and high-resolution scanning electron microscopy (HR-SEM). DLS measurements reveal that the size of the particles can be tuned from a hundred nanometers with a low polydispersity index (deposition of 2 layers) up to micrometer scale (deposition of 6 layers). Upon the deposition of each cellulose derivative, the particle charge is reversed, and pH is observed to considerably affect the process thus demonstrating the electrostatic driving force for LbL deposition. The HR-SEM characterization suggests that the shape of the core-shell particles formed is reminiscent of the spherical vesicle template. The development of biobased nano- and micro-containers by the alternating deposition of oppositely charged cellulose derivatives onto a vesicle template offers several advantages, such as simplicity, reproducibility, biocompatibility, low-cost, mild reaction conditions, and high controllability over particle size and composition of the shell.

Complexation of oppositely charged polymer: novel approaches for drug delivery

2021 ◽  
Vol 18 ◽  
Author(s):  
Ritesh Kumar Tiwari ◽  
Lalit Singh ◽  
Vaibhav Rastogi
Keyword(s):  
Drug Delivery ◽  
Polyelectrolyte Complex ◽  
Review Article ◽  
Polyelectrolyte Complexes ◽  
Complex Development ◽  
The Subject ◽  
Novel Approaches ◽  
Oppositely Charged ◽  
Delivery Technology ◽  
Made In

: The polyelectrolyte complexes (PECs) are adaptable definitions shaped by electrostatic interaction between biopolymers with inverse charges. Polyelectrolyte edifices comprise an exceptional class of polymeric mixtures comprising of polyions with inverse charges, which can be charged either cationically or anionically. Significant advancement has been made in the course of recent years towards new medication conveyance frameworks. The subject of broad essential and applied exploration has been on the marvel of interpolymer collaborations and polyelectrolyte complex development. Basically and applied polyelectrolytes raise on the grounds that the advantages of supportability are perceived in the scholarly world and in modern examination settings. Polyelectrolytes are a form of polymer that has endless ionizable practical arrangements. Ionized polyelectrolytes in arrangement can form a complex with oppositely charged particle called a polyelectrolyte complex. The review article emphasizes on PECs and their classification, characterization, as well as a critical analysis of the current research and applicability in drug delivery technology.

scholarly journals Macro- and Microphase Separated Protein-Polyelectrolyte Complexes: Design Parameters and Current Progress

Polymers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 578 ◽  
Author(s):  
Justin Horn ◽  
Rachel Kapelner ◽  
Allie Obermeyer
Keyword(s):  
Drug Delivery ◽  
Phase Separation ◽  
Food Processing ◽  
Design Parameters ◽  
Charge Neutrality ◽  
Polyelectrolyte Complexes ◽  
Overall Design ◽  
Potential Applications ◽  
Spherical Micelles ◽  
Oppositely Charged

Protein-containing polyelectrolyte complexes (PECs) are a diverse class of materials, composed of two or more oppositely charged polyelectrolytes that condense and phase separate near overall charge neutrality. Such phase-separation can take on a variety of morphologies from macrophase separated liquid condensates, to solid precipitates, to monodispersed spherical micelles. In this review, we present an overview of recent advances in protein-containing PECs, with an overall goal of defining relevant design parameters for macro- and microphase separated PECs. For both classes of PECs, the influence of protein characteristics, such as surface charge and patchiness, co-polyelectrolyte characteristics, such as charge density and structure, and overall solution characteristics, such as salt concentration and pH, are considered. After overall design features are established, potential applications in food processing, biosensing, drug delivery, and protein purification are discussed and recent characterization techniques for protein-containing PECs are highlighted.

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