Practical synthesis of 2'(3')-O-aminoacyl derivatives of CpA

1979 ◽  
Vol 44 (11) ◽  
pp. 3321-3326 ◽  
Author(s):  
Jiří Smrt ◽  
Jiří Jonák
Keyword(s):  
Formic Acid ◽  
Trifluoroacetic Acid ◽  
Practical Synthesis ◽  
Derivatives Of

N-Tert-butyloxycarbonyl-L-phenylalanine reacts with 1 equivalent of 1,1'-carbonyldiimidazole and 5'-O-dimethoxytrityl-2'-tetrahydropyranyl-N4-dimethylaminomethylenecytidylyl-(3' 5')-N6-dimethylaminomethyleneadenosine (I) and affords 2'(3')-O-(N-tert-butyloxycarbonyl)-L-phenylalanyl derivative II. The compound II gives by the action of formic acid in aqueous 1-butanol the 2'-O-tetrahydropyranylcytidylyl-(3' 5')-2'(3)-O-(tert-butyloxycarbonyl)-L-phenylalanyladenosine (III), which affords cytidyl-(3' 5')-2'(3')-O-L-phenylalanyladenosine (IV) by treatment with 95% aqueous trifluoroacetic acid.

Confirmatory Tests for Aflatoxin B1

1964 ◽  
Vol 47 (5) ◽  
pp. 801-803 ◽  
Author(s):  
Peter John Andrellos ◽  
George R Reid
Keyword(s):  
Acetic Acid ◽  
Thin Layer ◽  
Formic Acid ◽  
Thionyl Chloride ◽  
Aflatoxin B1 ◽  
Trifluoroacetic Acid ◽  
Reaction Products ◽  
Confirmatory Tests ◽  
Aflatoxin B ◽  
Layer Chromatography

Abstract Three confirmatory tests have been devised to identify aflatoxin B±. Portions of the isolated toxin are treated with formic acid-thionyl chloride, acetic acid-thionyl chloride, and trifluoroacetic acid, respectively, and aliquots of the three fluorescent reaction products are spotted on thin-layer chromatography plates. Standards treated with each of the three reagents, plus an untreated standard, are spotted on the same plate, and after development the spots are compared under ultraviolet light.

A Practical Synthesis of Isomerically Pure 1,10-Difunctionalized Derivatives of the [closo-1-CB9H10] Anion

2005 ◽  
Vol 44 (25) ◽  
pp. 9561-9566 ◽  
Author(s):  
Bryan Ringstrand ◽  
Andrzej Balinski ◽  
Andreas Franken ◽  
Piotr Kaszynski
Keyword(s):  
Practical Synthesis ◽  
Derivatives Of

Alternate, Easy and Practical Synthesis of Allylamines from Acetyl Derivatives of Baylis—Hillman Adducts Using Methanolic Ammonia.

ChemInform ◽  
2006 ◽  
Vol 37 (28) ◽  
Author(s):  
Richa Pathak ◽  
Vijay Singh ◽  
Som N. Nag ◽  
Sanjeev Kanojiya ◽  
Sanjay Batra
Keyword(s):  
Practical Synthesis ◽  
Derivatives Of ◽  
Methanolic Ammonia

The ring-chain equilibrium in derivatives of 5-nitro-1, 2, 3, 4-tetrahydropyrimidine in trifluoroacetic acid

Tetrahedron ◽  
1977 ◽  
Vol 33 (15) ◽  
pp. 1979-1981 ◽  
Author(s):  
H. Piotrowska ◽  
W. Sas ◽  
T. Urbański
Keyword(s):  
Trifluoroacetic Acid ◽  
Derivatives Of

scholarly journals Synthesis and characterization of a series of 1,3,5-trisubstituted-2-pyrazolines derivatives using methanoic acid under thermal condition

2009 ◽  
Vol 74 (12) ◽  
pp. 1371-1376 ◽  
Author(s):  
Behrooz Maleki ◽  
Davood Azarifar ◽  
Khodaverdian Moghaddam ◽  
Fatemeh Hojati ◽  
Mostafa Gholizadeh ◽  
...  
Keyword(s):  
Formic Acid ◽  
Thermal Condition ◽  
Synthesis And Characterization ◽  
Unsaturated Ketones ◽  
Practical Synthesis ◽  
Methanoic Acid

An efficient and practical synthesis of 1,3,5-trisubstituted 2-pyrazoline structures was achieved through cyclization of phenylhydrazine with ?,? -unsaturated ketones (chalcones) using methanoic acid (formic acid) as catalyst under thermal condition.

A Practical Synthesis of 3β-Amino-5-Cholestene

2013 ◽  
Vol 830 ◽  
pp. 151-154 ◽  
Author(s):  
Yue Hai You ◽  
Shan Shan Gong ◽  
Qi Sun
Keyword(s):  
Practical Method ◽  
Synthetic Route ◽  
Medicinal Value ◽  
Practical Synthesis ◽  
Derivatives Of ◽  
Substantial Interest

Derivatives of 3β-amino-5-cholestene are of substantial interest to chemical biologists and have potential medicinal value. A novel and practical method for the preparation of 3β-amino-5-cholestene from inexpensive cholesterol has been developed. To synthesize the epicholesterol intermediate, the KO2 method reported by Corey and coworkers was applied in this synthetic route and solved the problems of the known synthetic route involving epicholesterol intermediate.

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