scholarly journals Iodometric Detection of Haemophilus influenzae Beta-Lactamase: Rapid Presumptive Test for Ampicillin Resistance

1975 ◽  
Vol 7 (3) ◽  
pp. 265-270 ◽  
Author(s):  
B. W. Catlin
Keyword(s):  
Haemophilus Influenzae ◽  
Beta Lactamase ◽  
Ampicillin Resistance

scholarly journals Characterization of non-beta-lactamase-mediated ampicillin resistance in Haemophilus influenzae.

1984 ◽  
Vol 26 (2) ◽  
pp. 235-244 ◽  
Author(s):  
P M Mendelman ◽  
D O Chaffin ◽  
T L Stull ◽  
C E Rubens ◽  
K D Mack ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Beta Lactamase ◽  
Ampicillin Resistance

scholarly journals Detection of beta-lactamase-negative ampicillin resistance in Haemophilus influenzae in Belgium

2019 ◽  
Vol 93 (3) ◽  
pp. 243-249 ◽  
Author(s):  
Lise Schotte ◽  
Magali Wautier ◽  
Delphine Martiny ◽  
Denis Piérard ◽  
Melissa Depypere
Keyword(s):  
Haemophilus Influenzae ◽  
Beta Lactamase ◽  
Ampicillin Resistance

scholarly journals Antimicrobial Resistance among Respiratory Pathogens in Spain: Latest Data and Changes over 11 Years (1996-1997 to 2006-2007)

2010 ◽  
Vol 54 (7) ◽  
pp. 2953-2959 ◽  
Author(s):  
Emilio Pérez-Trallero ◽  
Jose E. Martín-Herrero ◽  
Ana Mazón ◽  
Celia García-Delafuente ◽  
Purificación Robles ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Antimicrobial Resistance ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Temporal Trends ◽  
Surveillance Study ◽  
Respiratory Pathogens ◽  
Ampicillin Resistance ◽  
Increasing Trend

ABSTRACT A nationwide multicenter susceptibility surveillance study (Susceptibility to the Antimicrobials Used in the Community in España [SAUCE] project), SAUCE-4, including 2,559 Streptococcus pneumoniae, 2,287 Streptococcus pyogenes, and 2,736 Haemophilus influenzae isolates was carried out from May 2006 to June 2007 in 34 Spanish hospitals. Then, the results from SAUCE-4 were compared to those from all three previous SAUCE studies carried out in 1996-1997, 1998-1999, and 2001-2002 to assess the temporal trends in resistance and the phenotypes of resistance over the 11-year period. In SAUCE-4, on the basis of the CLSI breakpoints, penicillin (parenteral, nonmeningitis breakpoint) and cefotaxime were the antimicrobials that were the most active against S. pneumoniae (99.8% and 99.6%, respectively). Only 0.9% of isolates had a penicillin MIC of ≥2 μg/ml. In S. pyogenes, nonsusceptibility to erythromycin was observed in 19.4% of isolates. Among the H. influenzae isolates, a β-lactamase-positive prevalence of 15.7% was found. A statistically significant temporal decreasing trend over the 11-year period was observed for nonsusceptibility (from 60.0% to 22.9%) and resistance (from 36.5% to 0.9%) to penicillin and for the proportion of erythromycin-resistant isolates of S. pneumoniae of the macrolide-lincosamide-streptogramin B (MLSB) phenotype (from 98.4% to 81.3%). A similar trend was observed for the prevalence of ampicillin resistance (from 37.6% to 16.1%), β-lactamase production (from 25.7% to 15.7%), and β-lactamase-negative ampicillin resistance (BLNAR) in H. influenzae (from 13.5% to 0.7%). Among erythromycin-resistant isolates of S. pyogenes, a significant increasing trend in the prevalence of MLSB was observed (from 7.0% to 35.5%). SAUCE-4 confirms a generalized decline in the resistance of the main respiratory pathogens to the antimicrobials as well as a shift in their resistance phenotypes.

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