scholarly journals Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex

2019 ◽  
Vol 63 (6) ◽  
Author(s):  
Chloé Loiseau ◽  
Daniela Brites ◽  
Irmgard Moser ◽  
Francesc Coll ◽  
Christine Pourcel ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Mycobacterium Bovis ◽  
In Silico ◽  
Mycobacterium Tuberculosis Complex ◽  
Tuberculosis Complex ◽  
Content Type ◽  
Causative Agents ◽  
Mycobacterium Africanum

ABSTRACT Using 894 phylogenetically diverse genomes of the Mycobacterium tuberculosis complex (MTBC), we simulated in silico the ability of the Hain Lifescience GenoType MTBC assay to differentiate the causative agents of tuberculosis. Here, we propose a revised interpretation of this assay to reflect its strengths (e.g., it can distinguish some strains of Mycobacterium canettii and variants of Mycobacterium bovis that are not intrinsically resistant to pyrazinamide) and limitations (e.g., Mycobacterium orygis cannot be differentiated from Mycobacterium africanum).

scholarly journals A Comprehensive Map of Mycobacterium tuberculosis Complex Regions of Difference

mSphere ◽  
2021 ◽  
Author(s):  
D. Bespiatykh ◽  
J. Bespyatykh ◽  
I. Mokrousov ◽  
E. Shitikov
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Genome Evolution ◽  
Mycobacterium Bovis ◽  
Mycobacterium Tuberculosis Complex ◽  
Mycobacterium Leprae ◽  
Tuberculosis Complex ◽  
Content Type ◽  
Its Phylogeny ◽  
Unique Event ◽  
Living Organisms

Reductive genome evolution is one of the most important and intriguing adaptation strategies of different living organisms to their environment. Mycobacterium offers several notorious examples of either naturally reduced ( Mycobacterium leprae ) or laboratory-reduced ( Mycobacterium bovis BCG) genomes. Mycobacterium tuberculosis complex has its phylogeny unambiguously framed by large sequence polymorphisms that present unidirectional unique event changes. In the present study, we curated all known regions of difference and analyzed both Mycobacterium tuberculosis and animal-adapted MTBC species.

scholarly journals Fatal Case of Polymicrobial Meningitis Caused by Cryptococcus liquefaciens and Mycobacterium tuberculosis Complex in a Human Immunodeficiency Virus-Infected Patient

2015 ◽  
Vol 53 (8) ◽  
pp. 2753-2755 ◽  
Author(s):  
César Conde-Pereira ◽  
Lia Rodas-Rodríguez ◽  
Manuel Díaz-Paz ◽  
Hilda Palacios-Rivera ◽  
Carolina Firacative ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Mycobacterium Tuberculosis ◽  
Infected Patient ◽  
Mycobacterium Tuberculosis Complex ◽  
Fatal Case ◽  
Central Nervous System Infections ◽  
Tuberculosis Complex ◽  
Content Type ◽  
Immunodeficiency Virus ◽  
Disseminated Disease

We describe a fatal case of polymicrobial meningitis in a human immunodeficiency virus-infected patient from Guatemala caused byCryptococcus liquefaciensandMycobacterium tuberculosiscomplex. Central nervous system infections caused concurrently by these species are extremely rare. This is also the first report of disseminated disease caused byC. liquefaciens.

Investigation of Mycobacterium bovis subsp. bovis Among the Strains of Mycobacterium tuberculosis Complex Isolated in Düzce Province, Turkey

2016 ◽  
Vol 50 (3) ◽  
pp. 392-400
Author(s):  
Cihadiye Elif ÖZTÜRK ◽  
İdris ŞAHİN ◽  
Şükrü ÖKSÜZ ◽  
Nida KILIÇ ◽  
Özge KILINÇEL ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Mycobacterium Bovis ◽  
Mycobacterium Tuberculosis Complex ◽  
Tuberculosis Complex
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