Hair-cell innervation by spiral ganglion cells in adult cats

Science ◽  
1982 ◽  
Vol 217 (4555) ◽  
pp. 175-177 ◽  
Author(s):  
N. Kiang ◽  
J. Rho ◽  
C. Northrop ◽  
M. Liberman ◽  
D. Ryugo
Keyword(s):  
Hair Cell ◽  
Ganglion Cells ◽  
Spiral Ganglion ◽  
Hair Cell Innervation ◽  
Adult Cats

scholarly journals Meta-Analysis—Correlation between Spiral Ganglion Cell Counts and Speech Perception with a Cochlear Implant

2021 ◽  
Vol 11 (2) ◽  
pp. 220-226
Author(s):  
Yew-Song Cheng ◽  
Mario A. Svirsky
Keyword(s):  
Speech Perception ◽  
Cochlear Implant ◽  
Ganglion Cells ◽  
Meta Analysis ◽  
Spiral Ganglion ◽  
Spiral Ganglion Cell ◽  
Cell Counts ◽  
Temporal Bones ◽  
The Relationship ◽  
Existing Data

The presence of spiral ganglion cells (SGCs) is widely accepted to be a prerequisite for successful speech perception with a cochlear implant (CI), because SGCs provide the only known conduit between the implant electrode and the central auditory system. By extension, it has been hypothesized that the number of SGCs might be an important factor in CI outcomes. An impressive body of work has been published on findings from the laborious process of collecting temporal bones from CI users and counting the number of SGCs to correlate those numbers with speech perception scores, but the findings thus far have been conflicting. We performed a meta-analysis of all published studies with the hope that combining existing data may help us reach a more definitive conclusion about the relationship between SGC count and speech perception scores in adults.

Otologic Histopathology of Fabry's Disease

1989 ◽  
Vol 98 (5) ◽  
pp. 359-363 ◽  
Author(s):  
Patricia A. Schachern ◽  
Michael M. Paparella ◽  
Donald A. Shea ◽  
Tae H. Yoon
Keyword(s):  
Temporal Bone ◽  
Ganglion Cells ◽  
Spiral Ganglion ◽  
Cell Loss ◽  
The Body ◽  
Spiral Ligament ◽  
Fabry’S Disease ◽  
Fabry's Disease ◽  
Temporal Bones ◽  
Spiral Ganglia

Fabry's disease is a rare progressive X-linked recessive disorder of glycosphingolipid metabolism. The accumulation of glycosphingolipids occurs in virtually all areas of the body, including the endothelial, perithelial, and smooth-muscle cells of blood vessels, the ganglion cells of the autonomic nervous system, and the glomeruli and tubules of the kidney. Although otologic symptoms have been described in these patients, to our knowledge there have been no temporal bone histopathologic reports. We describe the clinical histories, audiometric results, and temporal bone findings of two patients with this rare disorder. Both patients demonstrated a bilateral sloping sensorineural hearing loss audiometrically. Middle ear findings of seropurulent effusions and hyperplastic mucosa were seen in all four temporal bones. Strial and spiral ligament atrophy in all turns, and hair cell loss mainly in the basal turns, were also common findings. The number of spiral ganglion cells was reduced in all temporal bones; however, evidence of glycosphingolipid accumulation was not observed in the spiral ganglia.

Postnatal maturation of human spiral ganglion cells: Light and electron microscopic observations

1993 ◽  
Vol 67 (1-2) ◽  
pp. 211-219 ◽  
Author(s):  
Charlotte M. Chiong ◽  
Barbara J. Burgess ◽  
Joseph B. Nadol
Keyword(s):  
Ganglion Cells ◽  
Spiral Ganglion ◽  
Electron Microscopic ◽  
Postnatal Maturation

(−)-Epigallocatechin-3-gallate protects cultured spiral ganglion cells from H2O2-induced oxidizing damage

2004 ◽  
Vol 124 (4) ◽  
pp. 464-470 ◽  
Author(s):  
Dinghua Xie ◽  
Guohui Liu ◽  
Ganghua Zhu ◽  
Weijing Wu ◽  
Shenglei Ge
Keyword(s):  
Ganglion Cells ◽  
Spiral Ganglion
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