Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations

Science ◽  
2003 ◽  
Vol 299 (5607) ◽  
pp. 682-686 ◽  
Author(s):  
M. J. Levene
Keyword(s):  
Single Molecule ◽  
Zero Mode ◽  
High Concentrations ◽  
Single Molecule Analysis

scholarly journals Zero-mode waveguides can be made better: fluorescence enhancement with rectangular aluminum nanoapertures from the visible to the deep ultraviolet

2020 ◽  
Vol 2 (9) ◽  
pp. 4153-4160 ◽  
Author(s):  
Mikhail Baibakov ◽  
Aleksandr Barulin ◽  
Prithu Roy ◽  
Jean-Benoît Claude ◽  
Satyajit Patra ◽  
...  
Keyword(s):  
Single Molecule ◽  
Fluorescence Enhancement ◽  
Zero Mode ◽  
Metallic Films ◽  
Deep Ultraviolet ◽  
Single Molecule Analysis

Nanoapertures milled in metallic films called zero-mode waveguides (ZMWs) overcome the limitations of classical confocal microscopes by enabling single molecule analysis at micromolar concentrations with improved fluorescence brightness.

Zero-Mode Waveguides for Single-Molecule Analysis

2012 ◽  
Vol 41 (1) ◽  
pp. 269-293 ◽  
Author(s):  
Paul Zhu ◽  
Harold G. Craighead
Keyword(s):  
Single Molecule ◽  
Zero Mode ◽  
Single Molecule Analysis

Single-molecule detection and radiation control in solutions at high concentrations via a heterogeneous optical slot antenna

Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9103-9109 ◽  
Author(s):  
Chenglong Zhao ◽  
Yongmin Liu ◽  
Jing Yang ◽  
Jiasen Zhang
Keyword(s):  
Single Molecule ◽  
Emission Rate ◽  
Zero Mode ◽  
Single Molecule Detection ◽  
Slot Antenna ◽  
Radiation Control ◽  
High Concentrations

A heterogeneous optical slot antenna significantly enhances the single-molecule excitation and emission rate, which enables single-molecule detection in solutions at high concentrations, compared to a conventional zero-mode waveguide.

Design and Fabrication of Linear-shaped Zero Mode Waveguides for Single Molecule Observation of Kinesin and Fluorescent ATP

2017 ◽  
Vol 137 (6) ◽  
pp. 159-164
Author(s):  
Kazuya Fujimoto ◽  
Yuki Morita ◽  
Ryota Iino ◽  
Michio Tomishige ◽  
Hirofumi Shintaku ◽  
...  
Keyword(s):  
Single Molecule ◽  
Zero Mode
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