CLN7 is an organellar chloride channel regulating lysosomal function

Yayu Wang; Wenping Zeng; Bingqian Lin; Yichuan Yao; Canjun Li; Wenqi Hu; Haotian Wu; Jiamin Huang; Mei Zhang; Tian Xue; Dejian Ren; Lili Qu; Chunlei Cang

doi:10.1126/sciadv.abj9608

CLN7 is an organellar chloride channel regulating lysosomal function

Science Advances ◽

10.1126/sciadv.abj9608 ◽

2021 ◽

Vol 7 (51) ◽

Author(s):

Yayu Wang ◽

Wenping Zeng ◽

Bingqian Lin ◽

Yichuan Yao ◽

Canjun Li ◽

...

Keyword(s):

Chloride Channel ◽

Lysosomal Function

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Faculty Opinions recommendation of CLN7 is an organellar chloride channel regulating lysosomal function.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.741328958.793590689 ◽

2021 ◽

Author(s):

Sergio Grinstein

Keyword(s):

Chloride Channel ◽

Lysosomal Function

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New opportunities to investigate insecticide and acaricide chloride channel targets through their differential interactions with diverse chemical classes

10.1603/ice.2016.113654 ◽

2016 ◽

Author(s):

Sofia Iqbal

Keyword(s):

Chloride Channel

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Сloning and Functional Analysis of SaCLCc1, a Gene Belonging to Chloride Channel Family (CLC) from the Halophyte Suaeda altissima (L.) Pall

Доклады Академии наук ◽

10.31857/s086956520000062-1 ◽

2018 ◽

Vol 481 (1) ◽

pp. 104-107

Author(s):

Yurii Balnokin ◽

◽

Igor Karpichev ◽

Olga Mayorova ◽

Olga Nedelyaeva ◽

...

Keyword(s):

Functional Analysis ◽

Chloride Channel ◽

Suaeda Altissima

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Faculty Opinions recommendation of Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011143.177567 ◽

2003 ◽

Author(s):

Sue Malcolm

Keyword(s):

Alternative Splicing ◽

Myotonic Dystrophy ◽

Chloride Channel

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Faculty Opinions recommendation of Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12596.470079 ◽

2006 ◽

Author(s):

Klaus Bielefeldt

Keyword(s):

Healthy Volunteers ◽

Chloride Channel ◽

Gastrointestinal Transit ◽

Motor Functions ◽

Channel Activator

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Faculty Opinions recommendation of Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14195956.15708056 ◽

2012 ◽

Author(s):

Mark Hahn

Keyword(s):

Chloride Channel ◽

Natural Variation ◽

C Elegans

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Faculty Opinions recommendation of The granular chloride channel ClC-3 is permissive for insulin secretion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2573957.2227055 ◽

2010 ◽

Author(s):

Stephen Shears

Keyword(s):

Insulin Secretion ◽

Chloride Channel

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Faculty Opinions recommendation of Snapin-regulated late endosomal transport is critical for efficient autophagy-lysosomal function in neurons.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5530961.9798056 ◽

2011 ◽

Author(s):

Thomas Melia ◽

Julia Dancourt

Keyword(s):

Lysosomal Function ◽

Endosomal Transport

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Faculty Opinions recommendation of The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.716547833.792402807 ◽

2012 ◽

Author(s):

Youngseok Lee

Keyword(s):

Chloride Channel ◽

Anoctamin 1 ◽

Nociceptive Neurons ◽

Heat Sensor

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Faculty Opinions recommendation of Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717996262.793496408 ◽

2014 ◽

Author(s):

Rosa Puertollano

Keyword(s):

Lysosomal Function

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