MLL4 mediates differentiation and tumor suppression through ferroptosis

Shaun Egolf; Jonathan Zou; Amy Anderson; Cory L. Simpson; Yann Aubert; Stephen Prouty; Kai Ge; John T. Seykora; Brian C. Capell

doi:10.1126/sciadv.abj9141

MLL4 mediates differentiation and tumor suppression through ferroptosis

Science Advances ◽

10.1126/sciadv.abj9141 ◽

2021 ◽

Vol 7 (50) ◽

Author(s):

Shaun Egolf ◽

Jonathan Zou ◽

Amy Anderson ◽

Cory L. Simpson ◽

Yann Aubert ◽

...

Keyword(s):

Tumor Suppression

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Faculty Opinions recommendation of Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009075.120957 ◽

2002 ◽

Author(s):

Michele Pagano

Keyword(s):

Tumor Suppression ◽

Mutant Mice ◽

Specific Tumor

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Faculty Opinions recommendation of Chfr is required for tumor suppression and Aurora A regulation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1026726.323503 ◽

2005 ◽

Author(s):

Robert Abraham

Keyword(s):

Tumor Suppression ◽

Aurora A

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Faculty Opinions recommendation of FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1121865.578943 ◽

2008 ◽

Author(s):

Robert Abraham

Keyword(s):

Tumor Suppression

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Faculty Opinions recommendation of An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5422956.5381054 ◽

2010 ◽

Author(s):

Monica Bessler ◽

Philip Mason

Keyword(s):

Ribosomal Protein ◽

Tumor Suppression

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Faculty Opinions recommendation of A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718278091.793492052 ◽

2014 ◽

Author(s):

Michael B Yaffe ◽

Ian Cannell

Keyword(s):

Positive Feedback ◽

Tumor Suppression

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Tumor Suppression and Sensitization to Taxol Induces Apoptosis of EIA in Breast Cancer Cells

10.21236/ada438490 ◽

2005 ◽

Author(s):

Yong Liao

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Tumor Suppression ◽

Breast Cancer Cells

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Regulation of Estrogen-Responsive Gene Expression and Tumor Suppression by Transcriptional Cofactors

10.21236/ada437873 ◽

2005 ◽

Author(s):

Hua Xiao

Keyword(s):

Gene Expression ◽

Tumor Suppression ◽

Transcriptional Cofactors ◽

Estrogen Responsive Gene ◽

Responsive Gene

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Tumor Suppression by BRCA-1: A Critical Role at DNA Replication Forks

10.21236/ada463242 ◽

2006 ◽

Author(s):

Jean Gautier

Keyword(s):

Dna Replication ◽

Tumor Suppression ◽

Critical Role ◽

Replication Forks ◽

Brca 1

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Molecular Basis for BRCA2-mediated DNA Repair and Breast Tumor Suppression

10.21236/ada511986 ◽

2008 ◽

Author(s):

Julie Etchin

Keyword(s):

Dna Repair ◽

Tumor Suppression ◽

Breast Tumor ◽

Molecular Basis

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Mechanisms of Rerg-Mediated Tumor Suppression in Breast Cancer

10.21236/ada508444 ◽

2008 ◽

Author(s):

Ariella B. Hanker ◽

Channing J. Der

Keyword(s):

Breast Cancer ◽

Tumor Suppression

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