scholarly journals Evidence for the Interaction of A3 Adenosine Receptor Agonists at the Drug-Binding Site(s) of Human P-glycoprotein (ABCB1)

2019 ◽  
Vol 96 (2) ◽  
pp. 180-192 ◽  
Author(s):  
Biebele Abel ◽  
Dilip K. Tosh ◽  
Stewart R. Durell ◽  
Megumi Murakami ◽  
Shahrooz Vahedi ◽  
...  
Keyword(s):  
Binding Site ◽  
Adenosine Receptor ◽  
Drug Binding ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
Drug Binding Site ◽  
P Glycoprotein ◽  
A3 Adenosine Receptor

Design, synthesis and evaluation of N6-substituted 2-aminoadenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

MedChemComm ◽  
2014 ◽  
Vol 5 (2) ◽  
pp. 192-196 ◽  
Author(s):  
Shane M. Devine ◽  
Lauren T. May ◽  
Peter J. Scammells
Keyword(s):  
Adenosine Receptor ◽  
Design Synthesis ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor

A series of N6-substituted 2-aminoadenosine-5′-N-methylcarboxamides were synthesized from the versatile intermediate, O6-(benzotriazol-1-yl)-2-amino-2′,3′-O-isopropylideneinosine-5′-N-methylcarboxamide (1) and evaluated as A3 adenosine receptor agonists.

N6-Ethyl-2-alkynyl NECAs, Selective Human A3 Adenosine Receptor Agonists.

ChemInform ◽  
2006 ◽  
Vol 37 (31) ◽  
Author(s):  
Ran Zhu ◽  
Cynthia R. Frazier ◽  
Joel Linden ◽  
Timothy L. Macdonald
Keyword(s):  
Adenosine Receptor ◽  
Adenosine Receptor Agonists ◽  
Receptor Agonists ◽  
A3 Adenosine Receptor
Sign in / Sign up

Export Citation Format

Share Document