Optimization of Drug-Drug Interaction Study Design: Comparison of Minimal Physiologically Based Pharmacokinetic Models on Prediction of CYP3A Inhibition by Ketoconazole

2013 ◽  
Vol 41 (7) ◽  
pp. 1329-1338 ◽  
Author(s):  
Bing Han ◽  
Jialin Mao ◽  
Jenny Y. Chien ◽  
Stephen D. Hall
Keyword(s):  
Drug Interaction ◽  
Study Design ◽  
Pharmacokinetic Models ◽  
Interaction Study ◽  
Drug Interaction Study ◽  
Physiologically Based Pharmacokinetic Models ◽  
Physiologically Based Pharmacokinetic ◽  
Physiologically Based ◽  
Drug Drug Interaction ◽  
Design Comparison

scholarly journals ITC Commentary on Metformin Clinical Drug-Drug Interaction Study Design That Enables an Efficacy- and Safety-Based Dose Adjustment Decision

2018 ◽  
Vol 104 (5) ◽  
pp. 781-784 ◽  
Author(s):  
Maciej J. Zamek-Gliszczynski ◽  
Xiaoyan Chu ◽  
Jack A. Cook ◽  
Joseph M. Custodio ◽  
Aleksandra Galetin ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Study Design ◽  
Dose Adjustment ◽  
Efficacy And Safety ◽  
Interaction Study ◽  
Drug Interaction Study ◽  
Drug Drug Interaction ◽  
Clinical Drug
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