Simultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass Spectrometry

2012 ◽  
Vol 40 (7) ◽  
pp. 1389-1396 ◽  
Author(s):  
Yuichiro Sato ◽  
Aiji Miyashita ◽  
Takafumi Iwatsubo ◽  
Takashi Usui
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Liver Tissue ◽  
Human Liver ◽  
Protein Quantification ◽  
Tandem Mass ◽  
Human Liver Tissue ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

Validated assay for the evaluation of multiple glucuronidation activities in human liver microsomes via liquid chromatography-tandem mass spectrometry

RSC Advances ◽  
2014 ◽  
Vol 4 (99) ◽  
pp. 56132-56138 ◽  
Author(s):  
Rong Shi ◽  
Yuanyuan Yang ◽  
Jie Zhong ◽  
Tianming Wang ◽  
Yueming Ma
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Human Liver ◽  
Liver Microsomes ◽  
Tandem Mass ◽  
Activity Determination ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

A faster and more accurate LC-MS/MS method was established for the activity determination of multiple UGT isoforms in HLMs.

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