A liquid chromatography/tandem mass spectrometry method for detecting UGT-mediated bioactivation of drugs as theirN-acetylcysteine adducts in human liver microsomes

Hiroshi Harada; Takuro Endo; Yasunori Momose; Hiroshi Kusama

doi:10.1002/rcm.3912

A liquid chromatography/tandem mass spectrometry method for detecting UGT-mediated bioactivation of drugs as theirN-acetylcysteine adducts in human liver microsomes

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3912 ◽

2009 ◽

Vol 23 (5) ◽

pp. 564-570 ◽

Cited By ~ 14

Author(s):

Hiroshi Harada ◽

Takuro Endo ◽

Yasunori Momose ◽

Hiroshi Kusama

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Liver ◽

Liver Microsomes ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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An Enantiomer-Selective Liquid Chromatography-Tandem Mass Spectrometry Method for Methadone and EDDP Validated for Use in Human Plasma, Urine, and Liver Microsomes

Journal of Analytical Toxicology ◽

10.1093/jat/32.3.208 ◽

2008 ◽

Vol 32 (3) ◽

pp. 208-219 ◽

Cited By ~ 21

Author(s):

D. E. Moody ◽

S.-N. Lin ◽

Y. Chang ◽

L. Lamm ◽

M. K. Greenwald ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Liver Microsomes ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays

Drug Metabolism Letters ◽

10.2174/1872312810666161124143522 ◽

2017 ◽

Vol 10 (4) ◽

pp. 264-269 ◽

Cited By ~ 1

Author(s):

Siva Putluru ◽

Murali Matta ◽

Deepak Ahire ◽

Murali Subramanian ◽

Michael Sinz ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Enzyme Assays ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Trace Analysis of Multiclass Antibiotics in Food Products by Liquid Chromatography-Tandem Mass Spectrometry: Method Development

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.0c05778 ◽

2021 ◽

Vol 69 (5) ◽

pp. 1656-1666

Author(s):

Min Hu ◽

Yujie Ben ◽

Ming Hung Wong ◽

Chunmiao Zheng

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Trace Analysis ◽

Method Development ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Determination of antibiotics and their metabolites in milk by liquid chromatography-tandem mass spectrometry method

Food Control ◽

10.1016/j.foodcont.2021.108147 ◽

2021 ◽

pp. 108147

Author(s):

Fulya Tasci ◽

Hale Secilmis Canbay ◽

Mahmut Doganturk

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Development of liquid chromatography tandem mass spectrometry method to quantify cyclobutane pyrimidine dimer photolyase activity by detection of 15mer oligonucleotide as reaction product

Journal of Chromatography A ◽

10.1016/j.chroma.2019.460577 ◽

2020 ◽

Vol 1611 ◽

pp. 460577

Author(s):

A. Vallejos-Almirall ◽

C. Folch-Cano ◽

A. Rosas ◽

C. Vergara

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pyrimidine Dimer ◽

Tandem Mass ◽

Cyclobutane Pyrimidine Dimer ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Application of a liquid chromatography–tandem mass spectrometry method to the pharmacokinetics, bioavailability and tissue distribution of neohesperidin dihydrochalcone in rats

Xenobiotica ◽

10.3109/00498254.2013.861950 ◽

2013 ◽

Vol 44 (6) ◽

pp. 555-561 ◽

Cited By ~ 2

Author(s):

Xianqin Wang ◽

Yu Pan ◽

Ma Jianshe ◽

Shaohua Shi ◽

Xiaoyong Zheng ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tissue Distribution ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Liquid chromatography-tandem mass spectrometry method for simultaneous quantification of azoxystrobin and its metabolites, azoxystrobin free acid and 2-hydroxybenzonitrile, in greenhouse-grown lettuce

Food Additives & Contaminants Part A ◽

10.1080/19440049.2017.1382729 ◽

2017 ◽

Vol 34 (12) ◽

pp. 2173-2180 ◽

Cited By ~ 2

Author(s):

Maheswor Gautam ◽

Inge S. Fomsgaard

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Free Acid ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Simultaneous Quantification ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2009.06.003 ◽

2009 ◽

Vol 50 (5) ◽

pp. 872-877 ◽

Cited By ~ 19

Author(s):

Jong-Hwa Lee ◽

Young-Ah Woo ◽

In-Chang Hwang ◽

Choong-Yong Kim ◽

Dae-Duk Kim ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Rat Plasma ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Selective, sensitive, and rapid liquid chromatography – tandem mass spectrometry method for determination of Glimepiride in human plasma

Clinical Research and Regulatory Affairs ◽

10.3109/10601333.2011.647033 ◽

2012 ◽

Vol 29 (1) ◽

pp. 15-22

Author(s):

Lalit Dutta ◽

Syed Imran Ahmad ◽

Sanjeev Mishra ◽

Arshad Khuroo ◽

Tausif Monif

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea

Drug Testing and Analysis ◽

10.1002/dta.1583 ◽

2013 ◽

Vol 6 (9) ◽

pp. 898-908 ◽

Cited By ~ 20

Author(s):

György Székely ◽

Bruno Henriques ◽

Marco Gil ◽

Carlos Alvarez

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Experimental Design ◽

Tandem Mass Spectrometry ◽

Trace Analysis ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text