scholarly journals Characterization of Erythrocytic Uptake and Release and Disposition Pathways of Nitrite, Nitrate, Methemoglobin, and Iron-Nitrosyl Hemoglobin in the Human Circulation

2010 ◽  
Vol 38 (10) ◽  
pp. 1707-1713 ◽  
Author(s):  
Yuen Yi Hon ◽  
He Sun ◽  
André Dejam ◽  
Mark T. Gladwin
Keyword(s):  
Iron Nitrosyl ◽  
Nitrite Nitrate ◽  
Nitrosyl Hemoglobin ◽  
Uptake And Release

Synthesis and characterization of isomeric binuclear double-bridged alkylidene-tetraphenyldiphosphine and diphenylphosphido-methylenediphenylphosphine iron nitrosyl complexes

1987 ◽  
Vol 6 (2) ◽  
pp. 308-316 ◽  
Author(s):  
Chung Nin. Chau ◽  
Yuan Fu. Yu ◽  
Andrew. Wojcicki ◽  
Mario. Calligaris ◽  
Giorgio. Nardin ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Nitrosyl Complexes ◽  
Iron Nitrosyl ◽  
Iron Nitrosyl Complexes

scholarly journals Characterization of a Culturable “Gastrospirillum hominis” (Helicobacter heilmannii) Strain Isolated from Human Gastric Mucosa

1999 ◽  
Vol 37 (4) ◽  
pp. 1069-1076 ◽  
Author(s):  
L. P. Andersen ◽  
K. Boye ◽  
J. Blom ◽  
S. Holck ◽  
A. Nørgaard ◽  
...  
Keyword(s):  
Human Gastric Mucosa ◽  
Defibrinated Horse Blood ◽  
Helicobacter Felis ◽  
Helicobacter Heilmannii ◽  
Gastrospirillum Hominis ◽  
Horse Blood ◽  
H Pylori ◽  
Microaerobic Conditions ◽  
Nitrite Nitrate

Spiral organisms were isolated from an antral gastric mucosal biopsy specimen from a dyspeptic patient with gastritis. Only corkscrew-shaped organisms resembling “Gastrospirillum hominis” (“Helicobacter heilmannii”) but noHelicobacter pylori-like organisms were seen in histological sections. H. pylori was not cultured from specimens from this patient. On the basis of biochemical reactions, morphology, ultrastructure, and 16S DNA sequencing, the isolated “G. hominis” was shown to be a trueHelicobacter sp. very similar to Helicobacter felis and the “Gastrospirillum” but was separate from H. pylori. “G. hominis” is a pleomorphic gram-negative cork-screw-shaped, motile rod with 3 to 8 coils and a wavelength of about 1 μm. In contrast toH. pylori, it has up to 14 sheathed flagellar uni- or bipolar fibrils but no periplasmic fibrils. “G. hominis” grows under microaerobic conditions at 36 and 41°C on 7% lysed, defibrinated horse blood agar plates within 3 to 7 days and can be subcultured under microaerobic but not under anaerobic conditions on media similar to those used for H. pylori and H. felis. The small translucent colonies were, in contrast to those of H. felis, indistinguishable from those of H. pylori. “G. hominis” is, like H. pylori and H. felis, motile, is oxidase, catalase, nitrite, nitrate, and urease positive, and produces alkaline phosphatase and arginine arylamidase. Like H. pylori and H. felis, it is sensitive to cephalothin (30-μg disc), resistant to nalidixic acid (30-μg disc), and sensitive to most other antibiotics. The 16S DNA sequence clusters “G. hominis” together with “Gastrospirillum,” H. felis,Helicobacter bizzozeronii, Helicobacter salmonii, Helicobacter nemestrinae, Helicobacter acinonychis, and H. pylori.

scholarly journals Physicochemical characterization of municipal wastewater slaughterhouse for the implementation of a suitable treatment (Maradi city -Niger Republic

2015 ◽  
Vol 11 (6) ◽  
pp. 3656-3661
Author(s):  
Hassidou Saidou ◽  
Abass Maifada
Keyword(s):  
Organic Matter ◽  
Calcium Carbonate ◽  
Municipal Wastewater ◽  
Harmful Effect ◽  
Physicochemical Characterization ◽  
Physicochemical Characteristics ◽  
Slaughter House ◽  
Suitable Treatment ◽  
Nitrite Nitrate

The goal of this study is to determine physicochemical characteristics of the effluent of the municipal slaughter-house of the Maradi city and to recommend a suitable treatment allowing it’s recycling, thus reducing the harmful effect which undergoes the receiving environment. The experimental results obtained showed that average values of pH, temperature, turbidity and conductivity are respectively of 7.3, 26.6°C, 326 NTU and 4720 µs/cm. Average concentrations in phosphorus, phosphate, nitrite, nitrate, calcium, calcium carbonate, magnesium, iron, fluor and organic matter, in milligram per liter, are: 0.73, 2.23, 1.7, 211.64, 148.33, 8.53, 42, 9.24, 0.15, 32.08 and 426.67, respectively.

Cationic metal nitrosyl complexes. 6. Characterization of the 19-electron iron nitrosyl radical cation [Fe(NO)2LL'2]+

1986 ◽  
Vol 25 (19) ◽  
pp. 3497-3501 ◽  
Author(s):  
D. Ballivet-Tkatchenko ◽  
B. Nickel ◽  
A. Rassat ◽  
J. Vincent-Vaucquelin
Keyword(s):  
Radical Cation ◽  
Nitrosyl Complexes ◽  
Iron Nitrosyl ◽  
Metal Nitrosyl

Characterization of several novel iron nitrosyl porphyrins

1982 ◽  
Vol 104 (7) ◽  
pp. 2042-2044 ◽  
Author(s):  
L. W. Olson ◽  
D. Schaeper ◽  
D. Lancon ◽  
K. M. Kadish
Keyword(s):  
Iron Nitrosyl

Oxidation of Iron-nitrosyl-hemoglobin by Dehydroascorbic Acid Releases Nitric Oxide to Form Nitrite in Human Erythrocytes†

Biochemistry ◽  
2008 ◽  
Vol 47 (9) ◽  
pp. 2989-2996 ◽  
Author(s):  
Nathawut Sibmooh ◽  
Barbora Piknova ◽  
Fabiola Rizzatti ◽  
Alan N. Schechter
Keyword(s):  
Nitric Oxide ◽  
Dehydroascorbic Acid ◽  
Human Erythrocytes ◽  
Iron Nitrosyl ◽  
Nitrosyl Hemoglobin

Potential of Angeli’s Salt To Reduce Nitric Oxide Scavenging in Hemolysis.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 3788-3788
Author(s):  
Daniel B. Kim-Shapiro ◽  
Xiaojun He ◽  
Ivan Azarov ◽  
Jodi Richardson ◽  
S. Bruce King ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sickle Cell ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Cell Disease ◽  
Free Hemoglobin ◽  
Angeli's Salt ◽  
Iron Nitrosyl ◽  
Sickle Cell Crisis ◽  
No Bioavailability ◽  
Nitrosyl Hemoglobin

Abstract Since cell-free hemoglobin (Hb) scavenges nitric oxide (NO) more effectively than that encapsulated in the red blood cell (RBC), hemolysis reduces NO bioavailability with pathological consequences in sickle cell disease and other hemolytic anemias, paroxysmal nocturnal hemoglobinuria, thalassemia intermedia, malaria, and cardiopulomonary bypass. The ability of the cell-free Hb to scavenge NO is reduced when the Hb is converted from its oxygenated form (HbO2) to its oxidized form, methemoglobin (MetHb). We show that Angeli’s salt (AS) can convert two OxyHb to two MetHb molecules through its release of nitroxyl (HNO). AS also further converts the MetHb to less potentially oxidative forms: nitrite bound MetHb and iron-nitrosyl hemoglobin. We also show that, due to the fast reactivity of HNO with Hb (like NO), AS preferentially reacts with cell-free rather than RBC encapsulated Hb. In conditions simulating sickle cell crisis, within six minutes, AS converted 45 ± 12% of cell-free Hb to non-NO scavenging forms (MetHb and iron-nitrosyl Hb) and only converted 0.4 ± 0.3% of RBC encapsulated Hb (n=3). Similar preferential reactivity was observed under other physiologically relevant conditions. We conclude that, as AS preferentially reacts with cell-free Hb compared to RBC encapsulated Hb, converting it to species that do not effectively scavenge NO, it is has promise as a treatment for increasing NO biavailability in conditions associated with hemolysis.

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