EVALUATION OF TIME-DEPENDENT INACTIVATION OF CYP3A IN CRYOPRESERVED HUMAN HEPATOCYTES

2005 ◽  
Vol 33 (6) ◽  
pp. 853-861 ◽  
Author(s):  
Ping Zhao ◽  
Kent L. Kunze ◽  
Caroline A. Lee
Keyword(s):  
Human Hepatocytes ◽  
Time Dependent ◽  
Dependent Inactivation

Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA)

2007 ◽  
Vol 31 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Linh M. Van ◽  
John Swales ◽  
Clare Hammond ◽  
Claire Wilson ◽  
Judith A. Hargreaves ◽  
...  
Keyword(s):  
Human Hepatocytes ◽  
Time Dependent ◽  
Dependent Inactivation ◽  
Kinetics Of

Differential Time-Dependent Inactivation of P450 3A4 and P450 3A5 by Raloxifene: A Key Role for C239 in Quenching Reactive Intermediates

2007 ◽  
Vol 20 (12) ◽  
pp. 1778-1786 ◽  
Author(s):  
Josh T. Pearson ◽  
Jan L. Wahlstrom ◽  
Leslie J. Dickmann ◽  
Santosh Kumar ◽  
James R. Halpert ◽  
...  
Keyword(s):  
Reactive Intermediates ◽  
Time Dependent ◽  
Dependent Inactivation

Time-Dependent Inactivation of Aromatase by 6-Alkylandrosta-1,4-diene-3,17-diones. Effects of Length and Configuration of the 6-Alkyl Group†

1996 ◽  
Vol 39 (5) ◽  
pp. 1033-1038 ◽  
Author(s):  
Mitsuteru Numazawa ◽  
Mariko Oshibe ◽  
Satoshi Yamaguchi ◽  
Mii Tachibana
Keyword(s):  
Alkyl Group ◽  
Time Dependent ◽  
Dependent Inactivation

Time-dependent inactivation of steroid C17(20) lyase by 17β-cyclopropyl ether-substituted steroids

1996 ◽  
Vol 6 (1) ◽  
pp. 97-100 ◽  
Author(s):  
Michael R. Angelastro ◽  
Angela L. Marquart ◽  
Philip M. Weintraub ◽  
Cynthia A. Gates ◽  
Marie E. Laughlin ◽  
...  
Keyword(s):  
Time Dependent ◽  
Dependent Inactivation

scholarly journals Rhodopsin kinase: Two mAbs binding near the carboxyl terminus cause time-dependent inactivation

2000 ◽  
Vol 97 (7) ◽  
pp. 3010-3015 ◽  
Author(s):  
C. Bruel ◽  
K. Cha ◽  
L. Niu ◽  
P. J. Reeves ◽  
H. G. Khorana
Keyword(s):  
Time Dependent ◽  
Carboxyl Terminus ◽  
Dependent Inactivation ◽  
Rhodopsin Kinase
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