Comparing two statistical models for low boom dose-response relationships with correlated responses

2021 ◽  
Vol 150 (4) ◽  
pp. A260-A260
Author(s):  
Aaron B. Vaughn ◽  
William Doebler ◽  
Kathryn Ballard ◽  
Jonathan Rathsam
Keyword(s):  
Dose Response ◽  
Statistical Models ◽  
Correlated Responses

A Fluoride Dose-response Evaluation in an Anticaries Clinical Trial

1992 ◽  
Vol 71 (6) ◽  
pp. 1286-1291 ◽  
Author(s):  
R.G. Marks ◽  
R. D'Agostino ◽  
J.E. Moorhead ◽  
A.J. Conti ◽  
L. Cancro
Keyword(s):  
Clinical Trial ◽  
Dental Caries ◽  
Dose Level ◽  
Dose Response ◽  
Statistical Models ◽  
Adverse Reactions ◽  
Response Relationship ◽  
Response Evaluation ◽  
Dose Response Relationship ◽  
Dose Levels

This study evaluated the dose-response relationship between four increasing levels of fluoride from 1000 to 2500 ppm F as sodium monofluorophosphate (MFP) and three-year dental caries increments, as measured by DMFS, DMFT, and DFS-A on 4424 schoolchildren. The results indicated consistent linear decreases in all three dental indices as the dose level increased to 2500 ppm F MFP, with slopes (average reductions) of 0.32 in DMFS for an increase of 1000 ppm F, 0.13 in DMFT, and 0.17 in DFS-A when all children were evaluated, p < 0.03 for each index. For children 11 years and older at baseline, the slopes quadrupled, p < 0.01 for each index. Age and baseline DMFS were shown to be the most important covariates to control for in the statistical models. No differences in adverse reactions, or other safety problems, were observed at the different dose levels.

Statistical models for correlated responses in graft patency assessment

1991 ◽  
Vol 12 (5) ◽  
pp. 660
Author(s):  
E. Marubini ◽  
M. Braga ◽  
N. Pirotta ◽  
A. Petroccione
Keyword(s):  
Statistical Models ◽  
Graft Patency ◽  
Correlated Responses

Dose-Response Relationships to Pancreozymin in Normal Subjects and Patients with Chronic Pancreatitis

1963 ◽  
Vol 45 (2) ◽  
pp. 209-214 ◽  
Author(s):  
Donald H. Hanscom ◽  
Armand Littman ◽  
Jack V. Pinto
Keyword(s):  
Chronic Pancreatitis ◽  
Dose Response ◽  
Normal Subjects
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