An optically transparent tissue mimicking phantom for monitoring the thermal lesion produced by high intensity focused ultrasound

2012 ◽  
Vol 131 (4) ◽  
pp. 3364-3364 ◽  
Author(s):  
Min Joo Choi ◽  
Sitaramanjaneya Reddy Guntur ◽  
Kang IL Lee ◽  
Dong Guk Paeng ◽  
Andrew Coleman
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Thermal Lesion ◽  
Optically Transparent

scholarly journals High Intensity Focused Ultrasound and Microbubble Induced Tissue Ablation: Effect of Treatment Parameters on Thermal Lesion Volume and Temperature

2021 ◽  
Author(s):  
Sonal Bhadane
Keyword(s):  
Therapeutic Effect ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Tissue Ablation ◽  
Lesion Volume ◽  
Thermal Lesion ◽  
Effect Of Treatment

Microbubble agents have been shown to increase therapeutic effect of HIFU (High intensity focused ultrasound). Here, the effects of treatment parameters on lesion volume and temperature are investigated.

Toward high-intensity focused ultrasound lesion quantification using compressive sensing theory

2017 ◽  
Vol 231 (12) ◽  
pp. 1152-1164
Author(s):  
Hadi Ghasemifard ◽  
Hamid Behnam ◽  
Jahan Tavakkoli
Keyword(s):  
Compressive Sensing ◽  
High Intensity ◽  
Wavelet Transforms ◽  
Focused Ultrasound ◽  
Lesion Detection ◽  
High Intensity Focused Ultrasound ◽  
Thermal Lesion ◽  
Thermal Lesions ◽  
Threshold Algorithm

Compressive sensing theory has in recent years been increasingly used in various pattern recognition applications. Compressive sensing theory makes it possible, under certain assumptions, to recover a signal or an image sampled below the Nyquist sampling limit. In this work, a new application of compressive sensing based on the threshold algorithm, in the area of controlling and monitoring of high-intensity focused ultrasound therapy, was investigated. In this work, a new method of high-intensity focused ultrasound lesion detection is presented based on a modified compressive sensing method in combination with the threshold algorithm and the wavelet transforms. In this study, analysis of the suggested method is performed using two sets of data: simulated and experimental ultrasound radio frequency data. The results of processing the data show that the proposed algorithm results in enhancement of the high-intensity focused ultrasound lesion contrast in comparison with the ultrasound B-mode and standard compressive sensing imaging methods. The results of the study show that the modified compressive sensing method could effectively detect thermal lesions in vitro. Comparing the estimated size of the thermal lesion (8.3 mm × 8.4 mm) using the proposed algorithm with the actual size of that from physical examination (10.1 mm × 9 mm) shows that we could detect high-intensity focused ultrasound thermal lesions with the difference of 0.8 mm × 0.5 mm.

scholarly journals Influence of High-Intensity Focused Ultrasound (HIFU) Ablation on Arteries: Ex Vivo Studies

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 485
Author(s):  
Yufeng Zhou ◽  
Wei Chun Daniel Lim
Keyword(s):  
High Intensity ◽  
High Speed ◽  
Focused Ultrasound ◽  
Ex Vivo ◽  
High Intensity Focused Ultrasound ◽  
Hydrodynamic Cavitation ◽  
Thermal Lesion ◽  
Hifu Ablation ◽  
Vessel Rupture ◽  
Gel Phantom

High-intensity focused ultrasound (HIFU) has been used to ablate solid tumors and cancers. Because of the hypervascular structure of the tumor and circulating blood inside it, the interaction between the HIFU burst and vessel is a critical issue in the clinical environment. Influences on lesion production and the potential of vessel rupture were investigated in this study for the efficiency and safety of clinical ablation. An extracted porcine artery was embedded in a transparent polyacrylamide gel phantom, with bovine serum albumin (BSA) as an indicator of the thermal lesion, and degassed water was driven through the artery sample. The HIFU focus was aligned to the anterior wall, middle of the artery, and posterior wall. After HIFU ablation, the produced lesion was photographically recorded, and then its size was quantified and compared with that in the gel phantom without artery. In addition, the bubble dynamics (i.e., generation, expansion, motion, and shrinkage of bubbles and their interaction with the artery) were captured using high-speed imaging. It was found that the presence of the artery resulted in a decrease in lesion size in both the axial and lateral directions. The characteristics of the lesion are dependent on the focus alignment. Acoustic and hydrodynamic cavitation play important roles in lesion production and interaction with the artery. Both thermal and mechanical effects were found on the surface of the artery wall after HIFU ablation. However, no vessel rupture was found in this ex vivo study.

scholarly journals Trans-Esophageal Cardiac Ablation Using High Intensity Focused Ultrasound: A New Minimally Invasive Therapy for Treating Arrhythmias

2018 ◽  
Author(s):  
Cyril Lafon ◽  
Paul Greillier
Keyword(s):  
Minimally Invasive ◽  
Real Time ◽  
Ultrasound Imaging ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Beating Heart ◽  
Minimally Invasive Therapy ◽  
High Intensity Focused Ultrasound ◽  
Thermal Lesion ◽  
Anatomical Guidance

Our research project at LabTau aims at developing a probe capable of delivering HIFU into the heart by a trans oesophageal approach for treating cardiac arrhythmia. Anatomical guidance is achieved with B-mode ultrasound imaging. The goal of the present study is to generate thermal lesion on beating heart of primate, where arrhythmia foci are present in humans, in order to prove the feasibility of the approach. Treatments will be monitored in real time with conventional and passive ultrafast elastography, and then with MRI. This original strategy for treating arrhythmia would avoid invasive insertion of catheter into the heart.

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