Detection of high intensity focused ultrasound induced cavitation activity in liver tissue

2012 ◽  
Vol 131 (4) ◽  
pp. 3211-3211
Author(s):  
Tingbo Fan ◽  
Zhenbo Liu ◽  
Xiasheng Guo ◽  
Dong Zhang
Keyword(s):  
High Intensity ◽  
Liver Tissue ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Cavitation Activity

scholarly journals Investigation of the Inertial Cavitation Activity of Sonosensitive and Biocompatible Nanoparticles for Drug Delivery Applications Employing High Intensity Focused Ultrasound

2019 ◽  
Vol 5 (1) ◽  
pp. 585-588
Author(s):  
Benedikt George ◽  
Michael Fink ◽  
Helmut Ermert ◽  
Stefan J. Rupitsch ◽  
Pia T. Hiltl ◽  
...  
Keyword(s):  
Drug Release ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Active Drug ◽  
Drug Carriers ◽  
High Intensity Focused Ultrasound ◽  
Activity Level ◽  
Inertial Cavitation ◽  
Cavitation Effect ◽  
Cavitation Activity

AbstractAn approach to improve chemotherapy, while minimizing side effects, is a local drug release close to the tumorous tissue. For this purpose, the active drug component is often bound to nanoparticles employed as drug carriers. In the present study, we investigate sonosensitive, biocompatible poly-(L)-lactic acid (PLA) nanoparticles, which shall be used as drug carriers. For drug release, High Intensity Focused Ultrasound (HIFU) will be employed to introduce inertial cavitation, which separates the active drug component from the drug carrier. The cavitation effect generates an acoustic noise signal, which characterizes the cavitation activity and is expected to serve simultaneously as an indicator for the release of the active drug component. Depending on the ultrasound frequency, different acoustic levels of the inertial cavitation activity were measured. Investigations using a setup for passive cavitation detection (PCD) deliver quantitative results regarding the frequency dependence of the cavitation activity level of nanoparticles and reference media.

Effect of high intensity focused ultrasound transducer F-number and waveform non-linearity on inertial cavitation activity

2018 ◽  
Vol 144 (3) ◽  
pp. 1824-1824 ◽  
Author(s):  
Christopher Bawiec ◽  
Christopher Hunter ◽  
Wayne Kreider ◽  
Adam D. Maxwell ◽  
Vera A. Khokhlova ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Ultrasound Transducer ◽  
Inertial Cavitation ◽  
Cavitation Activity

Characterization of extracorporeal ablation of normal and tumor-bearing liver tissue by high intensity focused ultrasound

1993 ◽  
Vol 19 (9) ◽  
pp. 803-813 ◽  
Author(s):  
Alain Sibille ◽  
Frédéric Prat ◽  
Jean-Yves Chapelon ◽  
Fatima Abou El Fadil ◽  
Luc Henry ◽  
...  
Keyword(s):  
High Intensity ◽  
Liver Tissue ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Tumor Bearing

Thermal Fixation of Swine Liver Tissue after Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation1

2014 ◽  
Vol 40 (7) ◽  
pp. 1564-1577 ◽  
Author(s):  
Frédéric Courivaud ◽  
Airazat M. Kazaryan ◽  
Alice Lund ◽  
Vivian C. Orszagh ◽  
Aud Svindland ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Intensity ◽  
Liver Tissue ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Swine Liver

Synergistic Ablation of Liver Tissue and Liver Cancer Cells with High-Intensity Focused Ultrasound and Ethanol

2014 ◽  
Vol 40 (8) ◽  
pp. 1869-1881 ◽  
Author(s):  
Nguyen H. Hoang ◽  
Hakm Y. Murad ◽  
Sithira H. Ratnayaka ◽  
Chong Chen ◽  
Damir B. Khismatullin
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
High Intensity ◽  
Liver Tissue ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Liver Cancer Cells

scholarly journals Ultrastructural observation of liver tissue ablation induced by high-intensity focused ultrasound

1997 ◽  
Vol 3 (3) ◽  
pp. 134-136 ◽  
Author(s):  
Shu-Qun Cheng ◽  
Xin-Da Zhou ◽  
Zhao-You Tang ◽  
Yao Yu ◽  
Su-Su Bao ◽  
...  
Keyword(s):  
High Intensity ◽  
Liver Tissue ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Tissue Ablation ◽  
Ultrastructural Observation
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