TH-EF-BRB-07: Novel Hardware and Software Platform for Intermediate Energy 4π Radiotherapy

2016 ◽  
Vol 43 (6Part47) ◽  
pp. 3895-3896
Author(s):  
K Woods ◽  
M Harrison ◽  
S Boucher ◽  
J McNevin ◽  
S Kutsaev ◽  
...  
Keyword(s):  
Intermediate Energy ◽  
Software Platform ◽  
4Π Radiotherapy

CYBER FRAC – software platform for modeling, optimization and monitoring of hydraulic fracturing operations

2019 ◽  
Vol 12 ◽  
pp. 64-68
Author(s):  
A.A. Erofeev ◽  
◽  
R.N. Nikitin ◽  
D.A. Mitrushkin ◽  
S.V. Golovin ◽  
...  
Keyword(s):  
Hydraulic Fracturing ◽  
Software Platform

Intramolecular Proton Transfer in the Isomerization of Hydroxyacetone: A Detailed Characterization Based on Reaction Force Analysis and the Bond Fragility Spectrum

2020 ◽  
Author(s):  
Wallace Derricotte ◽  
Huiet Joseph
Keyword(s):  
Chemical Potential ◽  
Reaction Force ◽  
Intramolecular Proton Transfer ◽  
Intermediate Energy ◽  
Force Analysis ◽  
Activation Energy Barrier ◽  
Detailed Characterization ◽  
Proton Transfers ◽  
Reaction Force Constant

The mechanism of isomerization of hydroxyacetone to 2-hydroxypropanal is studied within the framework of reaction force analysis at the M06-2X/6-311++G(d,p) level of theory. Three unique pathways are considered: (i) a step-wise mechanism that proceeds through formation of the Z-isomer of their shared enediol intermediate, (ii) a step-wise mechanism that forms the E-isomer of the enediol, and (iii) a concerted pathway that bypasses the enediol intermediate. Energy calculations show that the concerted pathway has the lowest activation energy barrier at 45.7 kcal mol<sup>-1</sup>. The reaction force, chemical potential, and reaction electronic flux are calculated for each reaction to characterize electronic changes throughout the mechanism. The reaction force constant is calculated in order to investigate the synchronous/asynchronous nature of the concerted intramolecular proton transfers involved. Additional characterization of synchronicity is provided by calculating the bond fragility spectrum for each mechanism.

Software platform for automated preparation and analytical processing of heterogeneous datasets

2020 ◽  
pp. 15-20 ◽  
Author(s):  
E. D. Avedyan ◽  
I. V. Voronkov
Keyword(s):  
Data Processing ◽  
Analytical Data ◽  
Volume Growth ◽  
Software Platform ◽  
External Data ◽  
Heterogeneous Datasets ◽  
Data Volume ◽  
Processing Resources ◽  
Modular Platform ◽  
Network Technologies

Summary: the article proposes new software platform for automating the processes of preprocessing and marking up datasets with the aim of further solving analytical problems such as image classification and processing textual and parametric information using neural network technologies. The software platform uses modern technologies and combines a large number of methods in the form of a modular platform, which can be supplemented as the tasks of analytical data processing become more complicated. The need to develop such a software platform is dictated primarily by the fact that, given the current level of data volume growth, the actual transition to deep data analytics remains unattainable without such software platforms, since confidentiality, access to information and the use of external data processing resources are required.

Fission product yields at intermediate energy

1998 ◽  
Author(s):  
V. A. Rubchenya ◽  
J. Äystö ◽  
P. Dendooven ◽  
S. Hankonen ◽  
A. Jokinen ◽  
...  
Keyword(s):  
Fission Product ◽  
Intermediate Energy ◽  
Product Yields ◽  
Fission Product Yields

scholarly journals Integrated multi-modality image-guided navigation for neurosurgery: open-source software platform using state-of-the-art clinical hardware

2021 ◽  
Author(s):  
Jonathan Shapey ◽  
Thomas Dowrick ◽  
Rémi Delaunay ◽  
Eleanor C. Mackle ◽  
Stephen Thompson ◽  
...  
Keyword(s):  
Skull Base ◽  
Open Source ◽  
Open Source Software ◽  
Skull Base Surgery ◽  
Patient Specific ◽  
Software Platform ◽  
Image Guided ◽  
Phantom Model ◽  
Technical Requirements ◽  
Navigated Ultrasound

Abstract Purpose Image-guided surgery (IGS) is an integral part of modern neuro-oncology surgery. Navigated ultrasound provides the surgeon with reconstructed views of ultrasound data, but no commercial system presently permits its integration with other essential non-imaging-based intraoperative monitoring modalities such as intraoperative neuromonitoring. Such a system would be particularly useful in skull base neurosurgery. Methods We established functional and technical requirements of an integrated multi-modality IGS system tailored for skull base surgery with the ability to incorporate: (1) preoperative MRI data and associated 3D volume reconstructions, (2) real-time intraoperative neurophysiological data and (3) live reconstructed 3D ultrasound. We created an open-source software platform to integrate with readily available commercial hardware. We tested the accuracy of the system’s ultrasound navigation and reconstruction using a polyvinyl alcohol phantom model and simulated the use of the complete navigation system in a clinical operating room using a patient-specific phantom model. Results Experimental validation of the system’s navigated ultrasound component demonstrated accuracy of $$<4.5\,\hbox {mm}$$ < 4.5 mm and a frame rate of 25 frames per second. Clinical simulation confirmed that system assembly was straightforward, could be achieved in a clinically acceptable time of $$<15\,\hbox {min}$$ < 15 min and performed with a clinically acceptable level of accuracy. Conclusion We present an integrated open-source research platform for multi-modality IGS. The present prototype system was tailored for neurosurgery and met all minimum design requirements focused on skull base surgery. Future work aims to optimise the system further by addressing the remaining target requirements.

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