SU-E-T-349: Effective Dose-Volume-Histogram Prediction Method Using Euclidean Distance Volume Histogram for Volumetric Modulated Arc Therapy to Treat Prostate Cancer

2015 ◽  
Vol 42 (6Part17) ◽  
pp. 3413-3413
Author(s):  
J. Shin ◽  
J. Liang ◽  
S. Schild ◽  
W. Wong ◽  
W. Liu
Keyword(s):  
Prostate Cancer ◽  
Effective Dose ◽  
Euclidean Distance ◽  
Volumetric Modulated Arc Therapy ◽  
Prediction Method ◽  
Dose Volume Histogram ◽  
Dose Volume ◽  
Arc Therapy ◽  
Treat Prostate Cancer

scholarly journals Dose–volume histogram analysis and clinical evaluation of knowledge-based plans with manual objective constraints for pharyngeal cancer

2020 ◽  
Vol 61 (3) ◽  
pp. 499-505 ◽  
Author(s):  
Takuya Uehara ◽  
Hajime Monzen ◽  
Mikoto Tamura ◽  
Kazuki Ishikawa ◽  
Hiroshi Doi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Volumetric Modulated Arc Therapy ◽  
Intensity Modulated Radiation Therapy ◽  
Target Volume ◽  
Dose Volume Histogram ◽  
Parotid Glands ◽  
Pharyngeal Cancer ◽  
Knowledge Based ◽  
Dose Volume ◽  
Arc Therapy

Abstract The present study aimed to evaluate whether knowledge-based plans (KBP) from a single optimization could be used clinically, and to compare dose–volume histogram (DVH) parameters and plan quality between KBP with (KBPCONST) and without (KBPORIG) manual objective constraints and clinical manual optimized (CMO) plans for pharyngeal cancer. KBPs were produced from a system trained on clinical plans from 55 patients with pharyngeal cancer who had undergone intensity-modulated radiation therapy or volumetric-modulated arc therapy (VMAT). For another 15 patients, DVH parameters of KBPCONST and KBPORIG from a single optimization were compared with CMO plans with respect to the planning target volume (D98%, D50%, D2%), brainstem maximum dose (Dmax), spinal cord Dmax, parotid gland median and mean dose (Dmed and Dmean), monitor units and modulation complexity score for VMAT. The Dmax of spinal cord and brainstem and the Dmed and Dmean of ipsilateral parotid glands were unacceptably high for KBPORIG, although the KBPCONST DVH parameters met our goal for most patients. KBPCONST and CMO plans produced comparable DVH parameters. The monitor units of KBPCONST were significantly lower than those of the CMO plans (P < 0.001). Dose distribution of the KBPCONST was better than or comparable to that of the CMO plans for 13 (87%) of the 15 patients. In conclusion, KBPORIG was found to be clinically unacceptable, while KBPCONST from a single optimization was comparable or superior to CMO plans for most patients with head and neck cancer.

scholarly journals Delivery Parameter Variations and Early Clinical Outcomes of Volumetric Modulated Arc Therapy for 31 Prostate Cancer Patients: An Intercomparison of Three Treatment Planning Systems

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Shinichi Tsutsumi ◽  
Masako N. Hosono ◽  
Daisaku Tatsumi ◽  
Yoshitaka Miki ◽  
Yutaka Masuoka ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Planning Systems ◽  
Treatment Planning Systems ◽  
Dose Volume ◽  
Parameter Variations ◽  
Arc Therapy ◽  
The Mean ◽  
Mean Dose Rate ◽  
Early Clinical Outcomes

We created volumetric modulated arc therapy (VMAT) plans for 31 prostate cancer patients using one of three treatment planning systems (TPSs)—ERGO++, Monaco, or Pinnacle—and then treated those patients. A dose of 74 Gy was prescribed to the planning target volume (PTV). The rectum, bladder, and femur were chosen as organs at risk (OARs) with specified dose-volume constraints. Dose volume histograms (DVHs), the mean dose rate, the beam-on time, and early treatment outcomes were evaluated and compared. The DVHs calculated for the three TPSs were comparable. The mean dose rates and beam-on times for Ergo++, Monaco, and SmartArc were, respectively, 174.3 ± 17.7, 149.7 ± 8.4, and 185.8 ± 15.6 MU/min and 132.7 ± 8.4, 217.6 ± 13.1, and 127.5 ± 27.1 sec. During a follow-up period of 486.2 ± 289.9 days, local recurrence was not observed, but distant metastasis was observed in a single patient. Adverse events of grade 3 to grade 4 were not observed. The mean dose rate for Monaco was significantly lower than that for ERGO++ and SmartArc (P<0.0001), and the beam-on time for Monaco was significantly longer than that for ERGO++ and SmartArc (P<0.0001). Each TPS was successfully used for prostate VMAT planning without significant differences in early clinical outcomes despite significant TPS-specific delivery parameter variations.

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