TU-F-12A-09: GLCM Texture Analysis for Normal-Tissue Toxicity: A Prospective Ultrasound Study of Acute Toxicity in Breast-Cancer Radiotherapy

2014 ◽  
Vol 41 (6Part28) ◽  
pp. 482-482
Author(s):  
T Liu ◽  
X Yang ◽  
W Curran ◽  
M Torres
Keyword(s):  
Breast Cancer ◽  
Acute Toxicity ◽  
Texture Analysis ◽  
Normal Tissue ◽  
Cancer Radiotherapy ◽  
Normal Tissue Toxicity ◽  
Breast Cancer Radiotherapy ◽  
Ultrasound Study

Dosimetric Evaluation of Critical Organs at Risk in Mastectomized Left-Sided Breast Cancer Radiotherapy Using Breath-Hold Technique

2013 ◽  
Vol 99 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Ferrat Dincoglan ◽  
Murat Beyzadeoglu ◽  
Omer Sager ◽  
Kaan Oysul ◽  
Yelda Elcim Kahya ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Coronary Artery ◽  
Adjuvant Radiotherapy ◽  
Normal Tissue ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Breath Hold ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Tissue Sparing

Aims and background The aim of the study was to evaluate the dosimetric impact of the active breathing control-moderate deep inspiration breath-hold (ABC-mDIBH) technique on normal tissue sparing in locally advanced left-sided breast cancer radiotherapy. Methods and study design Twenty-seven consecutive patients with left-sided locally advanced breast cancer referred to our department for adjuvant radiotherapy were enrolled in the study. Each patient was scanned at free breathing and ABC-mDIBH for radiation treatment planning. Two separate radiotherapy treatment plans were generated with and without ABC-mDIBH to investigate the dosimetric impact of ABC-mDIBH in breast cancer radiotherapy. Results Between June 2011 and February 2012, 27 consecutive patients with left-sided locally advanced breast cancer referred to our department for adjuvant radiotherapy were enrolled in the study. Dose-volume parameters of left anterior descending coronary artery, lungs, heart, contralateral breast, esophagus and spinal cord were significantly reduced with the use of ABC-mDIBH ( P <0.001). Conclusions Our study revealed that the use of ABC-mDIBH in the practice of locally advanced mastectomized left-sided breast cancer radiotherapy improves normal tissue sparing with the expected potential of decreasing treatment-related morbidity and mortality. Moreover, the resultant reduction achieved with ABC in doses to the left anterior descending coronary artery, which plays a central role in cardiac perfusion, may have implications for decreasing the potential of radiation-induced cardiac morbidity and mortality.

PO-1480: Position in breast cancer radiotherapy: dosimetry and toxicity

2020 ◽  
Vol 152 ◽  
pp. S795-S796
Author(s):  
D. Hernandez ◽  
M.S. Talaya ◽  
C. Anson ◽  
P. Castro ◽  
M. Roch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Radiotherapy Dosimetry
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