SU-E-CAMPUS-T-01: Analysis of the Precision of Patient Set-Up, and Fidelity of the Delivered Dose Distribution in Proton Therapy of Ocular Tumors

2014 ◽  
Vol 41 (6Part22) ◽  
pp. 383-383
Author(s):  
A Trofimov ◽  
K Carpenter ◽  
HA Shih
2012 ◽  
Vol 39 (6Part16) ◽  
pp. 3795-3795
Author(s):  
Y Chen ◽  
L Zhang ◽  
L Court ◽  
Z Liao ◽  
X Zhu ◽  
...  

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
A. Pastorino ◽  
L. Todisco ◽  
E. Cazzulo ◽  
L. Berretta ◽  
A. Orecchia ◽  
...  

From mega-voltage portal images acquired on an electronic system (EPID), technological research has developed 3D and recently 4D volumetric verification modalities, allowing a direct visualization of the target, a direct comparison with the planning-TC and an optimization of the treatment (reduction of set-up errors, verification of the need for re-planning), leading to the very modern Image Guided RadioTherapy (IGRT). IGRT allows different technical solutions through direct or indirect visualization of the tumor and the acquisition of pre-treatment verification images, allowing to identify, quantify and correct errors related to set-up and organ-tumor motion, obtaining a greater compliance of the delivered dose, decreasing the risk of "geographic miss" and toxicity to healthy tissues and reducing the margins from CTV to PTV for the implementation of "dose escalation" protocols.


2009 ◽  
Vol 36 (6Part28) ◽  
pp. 2814-2814 ◽  
Author(s):  
F Attanasi ◽  
A Knopf ◽  
K Parodi ◽  
T Bortfeld ◽  
H Paganetti ◽  
...  

2014 ◽  
Vol 41 (6Part32) ◽  
pp. 552-552
Author(s):  
J Matney ◽  
P Park ◽  
L Court ◽  
X Zhu ◽  
H Li ◽  
...  

2015 ◽  
Vol 115 ◽  
pp. S255-S256
Author(s):  
A.J.A.J. Van de Schoot ◽  
J. Visser ◽  
Z. Van Kesteren ◽  
T.M. Janssen ◽  
C.R.N. Rasch ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Marie Lecornu ◽  
Paul Lesueur ◽  
Julia Salleron ◽  
Jacques Balosso ◽  
Dinu Stefan ◽  
...  

PurposeProton therapy (PT) can be a good option to achieve tumor control while reducing the probability of radiation induced toxicities compared to X-ray-based radiotherapy. However, there are still uncertainties about the effects of PT on the organs in direct contact with the irradiated volume. The aim of this prospective series was to report 6-month follow-up of clinical and functional optic neuropathy rates of patients treated by proton therapy using a standardized comprehensive optic examination.Methods and MaterialsStandardized ophthalmological examinations were performed to analyze subclinical anomalies in a systematic way before treatment and 6 months after the end of proton therapy with: Automatic visual field, Visual evoked potential (VEP) and optic coherence of tomography (OCT).ResultsFrom October 2018 to July 2020 we analyzed 81 eyes. No significant differences were found in the analysis of the clinical examination of visual functions by the radiation oncologist. However, considering VEP, the impairment was statistically significant for both fibers explored at 30’angle (p:0.007) and 60’angle (p <0.001). In patients with toxicity, the distance of the target volume from the optical pathways was more important with a p-value for 30’VEP at 0.035 and for 60’VEP at 0.039.ConclusionsThese results confirm uncertainties concerning relative biological effectiveness of proton therapy, linear energy transfer appears to be more inhomogeneous especially in areas close to the target volumes. The follow-up of patients after proton therapy is not an easy process to set up but it is necessary to improve our knowledges about the biological effects of proton therapy in real life. Our study which will continue during the coming years, suggests that follow-up with in-depth examinations such as VEP as a biomarker could improve the detection of early abnormalities.


2010 ◽  
Vol 37 (6Part22) ◽  
pp. 3278-3278 ◽  
Author(s):  
C Beltran ◽  
Y Jia ◽  
R Slopsema ◽  
D Yeung ◽  
Z Li

2006 ◽  
Vol 40 (5) ◽  
pp. 229-232
Author(s):  
A. Yu. Smyslov ◽  
I. N. Konchili ◽  
L. A. Lebedev ◽  
E. V. Khmelevskii

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