TH-C-144-02: Experimental Study of Discrete Prompt Gamma Lines for In-Vivo Proton Range Verification

2013 ◽  
Vol 40 (6Part33) ◽  
pp. 546-546
Author(s):  
J Verburg ◽  
K Riley ◽  
J Seco
Keyword(s):  
Experimental Study ◽  
Prompt Gamma ◽  
Range Verification

scholarly journals Characterization of prompt gamma ray emission for in vivo range verification in particle therapy: A simulation study

2019 ◽  
Vol 62 ◽  
pp. 20-32 ◽  
Author(s):  
Melek Zarifi ◽  
Susanna Guatelli ◽  
Yujin Qi ◽  
David Bolst ◽  
Dale Prokopovich ◽  
...  
Keyword(s):  
Simulation Study ◽  
Gamma Ray ◽  
Particle Therapy ◽  
Prompt Gamma ◽  
Gamma Ray Emission ◽  
Range Verification

scholarly journals First clinical application of a prompt gamma based in vivo proton range verification system

2016 ◽  
Vol 118 (2) ◽  
pp. 232-237 ◽  
Author(s):  
Christian Richter ◽  
Guntram Pausch ◽  
Steffen Barczyk ◽  
Marlen Priegnitz ◽  
Isabell Keitz ◽  
...  
Keyword(s):  
Clinical Application ◽  
Prompt Gamma ◽  
Verification System ◽  
Range Verification

Prompt Gamma Imaging for In Vivo Range Verification of Pencil Beam Scanning Proton Therapy

2017 ◽  
Vol 99 (1) ◽  
pp. 210-218 ◽  
Author(s):  
Yunhe Xie ◽  
El Hassane Bentefour ◽  
Guillaume Janssens ◽  
Julien Smeets ◽  
François Vander Stappen ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Prompt Gamma ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Gamma Imaging ◽  
Pencil Beam Scanning ◽  
Prompt Gamma Imaging ◽  
Range Verification

scholarly journals First clinical application of a prompt gamma based in vivo proton range verification using a knife-edge slit camera

2016 ◽  
Vol 118 ◽  
pp. S89-S90 ◽  
Author(s):  
C. Richter ◽  
G. Pausch ◽  
S. Barczyk ◽  
M. Priegnitz ◽  
I. Keitz ◽  
...  
Keyword(s):  
Clinical Application ◽  
Prompt Gamma ◽  
Knife Edge ◽  
Edge Slit ◽  
Range Verification

scholarly journals A Study of The Clinical Viability of A Prototype Compton Camera for Prompt Gamma Imaging Based Proton Beam Range Verification

2021 ◽  
Author(s):  
Jerimy Polf ◽  
Carlos A. Barajas ◽  
Gerson C. Kroiz ◽  
Stephen W. Peterson ◽  
Paul Maggi ◽  
...  
Keyword(s):  
Proton Beam ◽  
Prompt Gamma ◽  
Reconstruction Algorithms ◽  
Compton Camera ◽  
Detection Rates ◽  
Proton Beams ◽  
Proton Beam Radiotherapy ◽  
Beam Range ◽  
Range Verification

Abstract We present Compton camera (CC) based PG imaging for proton range verification at clinical dose rates. PG emission from a tissue-equivalent phantom during irradiation with clinical proton beams was measured with a prototype CC. Images were reconstructed of the raw measured data and of data processed with a neural network (NN) trained to identify “true” and “false” PG events. From these images, we determine if PG images produced by the prototype CC could provide clinically useful information about the in vivo range of the proton beams delivered during proton beam radiotherapy. NN processing of the data was found necessary to allow identification of the proton beam path from the PG images. Furthermore, to allow the localization of the end of the proton beam range with a precision of ≤ 3mm with the prototype CC, ~1 x 109 protons would need to be delivered, which is on the order of magnitude delivered for a standard proton radiotherapy treatment field. To obtain higher precision in beam range determination and to allow imaging a single proton pencil beam delivered within the full treatment field, further improvements in PG detection rates by the CC, NN data processing, and image reconstruction algorithms are needed.

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