WE-G-500-04: A Novel Technique for In-Vivo and Real-Time Range Verification Based On the Characteristic Prompt Gamma Time-Structure of Passively Modulated Proton Beams

2013 ◽  
Vol 40 (6Part30) ◽  
pp. 503-503
Author(s):  
M Testa ◽  
C Min ◽  
J Schuemann ◽  
J Verburg ◽  
H Lu ◽  
...  
Keyword(s):  
Real Time ◽  
Time Structure ◽  
Time Range ◽  
Prompt Gamma ◽  
Proton Beams ◽  
Novel Technique ◽  
Range Verification

scholarly journals A Study of The Clinical Viability of A Prototype Compton Camera for Prompt Gamma Imaging Based Proton Beam Range Verification

2021 ◽  
Author(s):  
Jerimy Polf ◽  
Carlos A. Barajas ◽  
Gerson C. Kroiz ◽  
Stephen W. Peterson ◽  
Paul Maggi ◽  
...  
Keyword(s):  
Proton Beam ◽  
Prompt Gamma ◽  
Reconstruction Algorithms ◽  
Compton Camera ◽  
Detection Rates ◽  
Proton Beams ◽  
Proton Beam Radiotherapy ◽  
Beam Range ◽  
Range Verification

Abstract We present Compton camera (CC) based PG imaging for proton range verification at clinical dose rates. PG emission from a tissue-equivalent phantom during irradiation with clinical proton beams was measured with a prototype CC. Images were reconstructed of the raw measured data and of data processed with a neural network (NN) trained to identify “true” and “false” PG events. From these images, we determine if PG images produced by the prototype CC could provide clinically useful information about the in vivo range of the proton beams delivered during proton beam radiotherapy. NN processing of the data was found necessary to allow identification of the proton beam path from the PG images. Furthermore, to allow the localization of the end of the proton beam range with a precision of ≤ 3mm with the prototype CC, ~1 x 109 protons would need to be delivered, which is on the order of magnitude delivered for a standard proton radiotherapy treatment field. To obtain higher precision in beam range determination and to allow imaging a single proton pencil beam delivered within the full treatment field, further improvements in PG detection rates by the CC, NN data processing, and image reconstruction algorithms are needed.

MO-AB-BRA-07: Prompt Gamma-Ray Spectroscopy for Range Verification of Clinical Proton Beams

2015 ◽  
Vol 42 (6Part27) ◽  
pp. 3548-3548
Author(s):  
J Verburg ◽  
T Bortfeld ◽  
J Seco
Keyword(s):  
Gamma Ray ◽  
Prompt Gamma ◽  
Proton Beams ◽  
Gamma Ray Spectroscopy ◽  
Range Verification

scholarly journals Author Correction: A Monte Carlo feasibility study for neutron based real-time range verification in proton therapy

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kristian Smeland Ytre-Hauge ◽  
Kyrre Skjerdal ◽  
John Mattingly ◽  
Ilker Meric
Keyword(s):  
Monte Carlo ◽  
Real Time ◽  
Feasibility Study ◽  
Proton Therapy ◽  
Time Range ◽  
Range Verification

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Range verification of passively scattered proton beams based on prompt gamma time patterns

2014 ◽  
Vol 59 (15) ◽  
pp. 4181-4195 ◽  
Author(s):  
Mauro Testa ◽  
Chul Hee Min ◽  
Joost M Verburg ◽  
Jan Schümann ◽  
Hsiao-Ming Lu ◽  
...  
Keyword(s):  
Prompt Gamma ◽  
Proton Beams ◽  
Scattered Proton ◽  
Time Patterns ◽  
Range Verification

scholarly journals Characterization of prompt gamma ray emission for in vivo range verification in particle therapy: A simulation study

2019 ◽  
Vol 62 ◽  
pp. 20-32 ◽  
Author(s):  
Melek Zarifi ◽  
Susanna Guatelli ◽  
Yujin Qi ◽  
David Bolst ◽  
Dale Prokopovich ◽  
...  
Keyword(s):  
Simulation Study ◽  
Gamma Ray ◽  
Particle Therapy ◽  
Prompt Gamma ◽  
Gamma Ray Emission ◽  
Range Verification
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